scholarly journals New BMSC-Laden Gelatin Hydrogel Formed in Situ by Dual-Enzymatic Cross-Linking Accelerates Dermal Wound Healing

ACS Omega ◽  
2019 ◽  
Vol 4 (5) ◽  
pp. 8334-8340 ◽  
Author(s):  
Minghao Yao ◽  
Junni Zhang ◽  
Feng Gao ◽  
Yihao Chen ◽  
Shanshan Ma ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cross Linking ◽  
Dermal Wound Healing ◽  
Gelatin Hydrogel ◽  
Dermal Wound

In Situ Forming and Rutin-Releasing Chitosan Hydrogels As Injectable Dressings for Dermal Wound Healing

2011 ◽  
Vol 12 (8) ◽  
pp. 2872-2880 ◽  
Author(s):  
Ngoc Quyen Tran ◽  
Yoon Ki Joung ◽  
Eugene Lih ◽  
Ki Dong Park
Keyword(s):  
Wound Healing ◽  
Dermal Wound Healing ◽  
In Situ Forming ◽  
Chitosan Hydrogels ◽  
Dermal Wound

scholarly journals Development of an in-situ forming, self-healing scaffold for dermal wound healing: in-vivo and in-vivo studies

2021 ◽  
pp. 112263
Author(s):  
Swati Sharma ◽  
Harishkumar Madhyastha ◽  
K. Laxmi Swetha ◽  
Kavya Sree Maravajjala ◽  
Archana Singh ◽  
...  
Keyword(s):  
Wound Healing ◽  
In Vivo Studies ◽  
Self Healing ◽  
Dermal Wound Healing ◽  
In Situ Forming ◽  
Dermal Wound

scholarly journals Ex vivoexpanded haematopoietic progenitor cells improve dermal wound healing by paracrine mechanisms

2009 ◽  
Vol 18 (5) ◽  
pp. 445-453 ◽  
Author(s):  
Christian Templin ◽  
Karsten Grote ◽  
Kai Schledzewski ◽  
Jelena-Rima Ghadri ◽  
Sabine Schnabel ◽  
...  
Keyword(s):  
Wound Healing ◽  
Progenitor Cells ◽  
Dermal Wound Healing ◽  
Dermal Wound

scholarly journals Augmentation of Dermal Wound Healing by Adipose Tissue-Derived Stromal Cells (ASC)

2018 ◽  
Vol 5 (4) ◽  
pp. 91 ◽  
Author(s):  
Joris van Dongen ◽  
Martin Harmsen ◽  
Berend van der Lei ◽  
Hieronymus Stevens
Keyword(s):  
Extracellular Matrix ◽  
Wound Healing ◽  
Adipose Tissue ◽  
Stromal Cells ◽  
Randomized Clinical Trials ◽  
Cell Types ◽  
Matrix Remodeling ◽  
Skin Wound Healing ◽  
Dermal Wound Healing ◽  
Dermal Wound

The skin is the largest organ of the human body and is the first line of defense against physical and biological damage. Thus, the skin is equipped to self-repair and regenerates after trauma. Skin regeneration after damage comprises a tightly spatial-temporally regulated process of wound healing that involves virtually all cell types in the skin. Wound healing features five partially overlapping stages: homeostasis, inflammation, proliferation, re-epithelization, and finally resolution or fibrosis. Dysreguled wound healing may resolve in dermal scarring. Adipose tissue is long known for its suppressive influence on dermal scarring. Cultured adipose tissue-derived stromal cells (ASCs) secrete a plethora of regenerative growth factors and immune mediators that influence processes during wound healing e.g., angiogenesis, modulation of inflammation and extracellular matrix remodeling. In clinical practice, ASCs are usually administered as part of fractionated adipose tissue i.e., as part of enzymatically isolated SVF (cellular SVF), mechanically isolated SVF (tissue SVF), or as lipograft. Enzymatic isolation of SVF obtained adipose tissue results in suspension of adipocyte-free cells (cSVF) that lack intact intercellular adhesions or connections to extracellular matrix (ECM). Mechanical isolation of SVF from adipose tissue destructs the parenchyma (adipocytes), which results in a tissue SVF (tSVF) with intact connections between cells, as well as matrix. To date, due to a lack of well-designed prospective randomized clinical trials, neither cSVF, tSVF, whole adipose tissue, or cultured ASCs can be indicated as the preferred preparation procedure prior to therapeutic administration. In this review, we present and discuss current literature regarding the different administration options to apply ASCs (i.e., cultured ASCs, cSVF, tSVF, and lipografting) to augment dermal wound healing, as well as the available indications for clinical efficacy.

scholarly journals The Effect of Thrombocytopenia on Dermal Wound Healing

2003 ◽  
Vol 120 (6) ◽  
pp. 1130-1137 ◽  
Author(s):  
Anna M. Szpaderska ◽  
Eric I. Egozi ◽  
Richard L. Gamelli ◽  
Luisa A. DiPietro
Keyword(s):  
Wound Healing ◽  
Dermal Wound Healing ◽  
Dermal Wound
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