scholarly journals Chemical Waltz of Organic Molecules “On Water”: Saline-Assisted Sustainable Regioselective Synthesis of Fluorogenic Heterobioconjugates via Click Reaction

ACS Omega ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 3582-3592 ◽  
Author(s):  
Yachana Jain ◽  
Ragini Gupta ◽  
Priya Yadav ◽  
Mitlesh Kumari
2019 ◽  
Vol 4 (2) ◽  
pp. 650-654 ◽  
Author(s):  
Abdulkadir Shube Hussen ◽  
Aparna Monga ◽  
Anuj Sharma

2016 ◽  
Vol 52 (99) ◽  
pp. 14188-14199 ◽  
Author(s):  
Fang Wei ◽  
Weiguo Wang ◽  
Yudao Ma ◽  
Chen-Ho Tung ◽  
Zhenghu Xu

Copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC) provides an efficient synthesis of 1,4-disubstituted 1,2,3-triazoles. This feature article highlights the recent progress on the regisoselective synthesis of multisubstituted 1,2,3-triazoles, which current click reaction (CuAAC) is unable to do.


RSC Advances ◽  
2014 ◽  
Vol 4 (75) ◽  
pp. 39790-39797 ◽  
Author(s):  
Deepak Kumar Joshi ◽  
Kunj Bihari Mishra ◽  
Vinod Kumar Tiwari ◽  
Subrato Bhattacharya

Newly synthesized Cu(i) with thiobenzoate complexes was found to catalyse the regioselective synthesis of glycoconjugate triazoles under click reaction.


ChemInform ◽  
2014 ◽  
Vol 45 (30) ◽  
pp. no-no
Author(s):  
Mahboobeh Nasr-Esfahani ◽  
Iraj Mohammadpoor-Baltork ◽  
Ahmad R. Khosropour ◽  
Majid Moghadam ◽  
Valiollah Mirkhani ◽  
...  

2017 ◽  
Vol 82 (9) ◽  
pp. 995-1007 ◽  
Author(s):  
Chander Kaushik ◽  
Krishan Kumar ◽  
Devinder Kumar ◽  
Satbir Mor ◽  
Ashwani Kumar ◽  
...  

Regioselective synthesis of some amide?ether-linked 1,4-disubstituted 1,2,3-triazoles was realized via the copper(I)-catalyzed click reaction of 1-(prop-2-ynyloxy)naphthalene, 2-(prop-2-ynyloxy)naphthalene and 1,4-bis-(prop-2-ynyloxy)benzene with 2-azido-N-substituted acetamides. The synthesized compounds were characterized by spectral techniques viz. FT-IR, 1H- -NMR, 13C-NMR, HRMS and evaluated for their in vitro antimicrobial activity against Bacillus subtilis, Staphylococcus aureus (Gram-positive bacteria), Pseudomonas aeruginosa, Escherichia coli (Gram-negative bacteria), Candida albicans and Aspergillus brasiliensis (fungi). Among the synthesized 1,4-disubstituted 1,2,3-triazoles, compound 13d displayed excellent antibacterial potential, while, compounds 7d and 13d appeared as potent fungicidal agents against the tested microbial strains. The docking simulation of the broad spectrum microbicidal disubstituted 1,2,3-triazole 13d into the active site of E. coli type II topoisomerase, DNA gyrase B enzyme was also investigated.


2014 ◽  
Vol 38 (7) ◽  
pp. 3015-3021 ◽  
Author(s):  
Arasappan Hemamalini ◽  
Thangamuthu Mohan Das

A facile regioselective synthesis of bis-triazologlycolipids, a class of organogelators, has been accomplished by “Click reaction”. The morphology and self-assembly of the gelators were examined by FESEM and HRTEM analysis.


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