scholarly journals Label-Free Electrochemical Immunosensor Based on Ionic Liquid Containing Dialdehyde As a Novel Linking Agent for the Antibody Immobilization

ACS Omega ◽  
2018 ◽  
Vol 3 (9) ◽  
pp. 11227-11232 ◽  
Author(s):  
Youming Shen ◽  
Guangyu Shen ◽  
Youyu Zhang
Keyword(s):  
Ionic Liquid ◽  
Electrochemical Immunosensor ◽  
Antibody Immobilization ◽  
Label Free

One-step immobilization antibodies using ferrocene-containing thiol aromatic aldehyde for the fabrication of a label-free electrochemical immunosensor

RSC Advances ◽  
2016 ◽  
Vol 6 (115) ◽  
pp. 114019-114023 ◽  
Author(s):  
Xiaoying Liu ◽  
Qiang Li ◽  
Lijuan Chen ◽  
Jiheng Zhou ◽  
Meiling Liu ◽  
...  
Keyword(s):  
Aromatic Aldehyde ◽  
Electrochemical Immunosensor ◽  
Antibody Immobilization ◽  
Label Free ◽  
One Step

This work focuses on a facile method for antibody immobilization to fabricate a label-free electrochemical immunosensor using ferrocene-containing thiol aromatic aldehyde (FcSA) synthesized by us.

The fabrication of a label-free electrochemical immunosensor using an aldehyde-functionalized pyridinium salt for antibody immobilization

2016 ◽  
Vol 8 (37) ◽  
pp. 6782-6786
Author(s):  
Chunxiang Zhang ◽  
Yibing Pi ◽  
Youming Shen ◽  
Guangyu Shen ◽  
Youyu Zhang ◽  
...  
Keyword(s):  
Pyridinium Salt ◽  
Electrochemical Immunosensor ◽  
Antibody Immobilization ◽  
Label Free

This paper reported a strategy based on the use of an aldehyde-functionalized pyridinium salt for the fabrication of a label-free electrochemical immunosensor.

A novel label-free electrochemical immunosensor based on aldehyde-terminated ionic liquid

Talanta ◽  
2017 ◽  
Vol 175 ◽  
pp. 347-351 ◽  
Author(s):  
Youming Shen ◽  
Guangyu Shen ◽  
Youyu Zhang ◽  
Chunxiang Zhang ◽  
Haitao Li
Keyword(s):  
Ionic Liquid ◽  
Electrochemical Immunosensor ◽  
Label Free

Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

2020 ◽  
Vol 28 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan ◽  
Mustafa Özyürek
Keyword(s):  
Prostate Specific Antigen ◽  
Nanostructured Materials ◽  
Specific Antigen ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Electrochemical Immunosensors ◽  
Metal Metal ◽  
Different Types ◽  
Sandwich Type ◽  
Carbon Based Nanomaterials

: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This surveys recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

scholarly journals Ultrasensitive and label free electrochemical immunosensor for detection of ROR1 as an oncofetal biomarker using gold nanoparticles assisted LDH/rGO nanocomposite

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rozita Abolhasan ◽  
Balal Khalilzadeh ◽  
Hadi Yousefi ◽  
Sahar Samemaleki ◽  
Forough Chakari-Khiavi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Flexible Structures ◽  
Modified Electrodes ◽  
Electrochemical Immunosensor ◽  
Lymphocytic Leukemia ◽  
Orphan Receptor ◽  
Detection Sensitivity ◽  
Label Free ◽  
Serum Samples ◽  
Limit Of Quantification

AbstractIn the present article, we developed a highly sensitive label-free electrochemical immunosensor based on NiFe-layered double hydroxides (LDH)/reduced graphene oxide (rGO)/gold nanoparticles modified glassy carbon electrode for the determination of receptor tyrosine kinase-like orphan receptor (ROR)-1. In this electrochemical immunoassay platform, NiFe-LDH/rGO was used due to great electron mobility, high specific surface area and flexible structures, while Au nanoparticles were prepared and coated on the modified electrodes to improve the detection sensitivity and ROR1 antibody immobilizing (ROR1Ab). The modification procedure was approved by using cyclic voltammetry and differential pulse voltammetry based on the response of peak current to the step by step modifications. Under optimum conditions, the experimental results showed that the immunosensor revealed a sensitive response to ROR1 in the range of 0.01–1 pg mL−1, and with a lower limit of quantification of 10 attogram/mL (10 ag mL−1). Furthermore, the designed immunosensor was applied for the analysis of ROR1 in several serum samples of chronic lymphocytic leukemia suffering patients with acceptable results, and it also exhibited good selectivity, reproducibility and stability.

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

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