scholarly journals Mechanistic Insight into Size-Dependent Enhanced Cytotoxicity of Industrial Antibacterial Titanium Oxide Nanoparticles on Colon Cells Because of Reactive Oxygen Species Quenching and Neutral Lipid Alteration

ACS Omega ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 1244-1262 ◽  
Author(s):  
Suresh K. Verma ◽  
Ealisha Jha ◽  
Pritam Kumar Panda ◽  
Arun Thirumurugan ◽  
S. K. S. Parashar ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Neutral Lipid ◽  
Titanium Oxide ◽  
Oxide Nanoparticles ◽  
Oxygen Species ◽  
Titanium Oxide Nanoparticles ◽  
Colon Cells ◽  
Size Dependent ◽  
Mechanistic Insight ◽  
Insight Into

Size-dependent antimycobacterial activity of titanium oxide nanoparticles against Mycobacterium tuberculosis

2019 ◽  
Vol 7 (27) ◽  
pp. 4338-4346 ◽  
Author(s):  
Vaikundamoorthy Ramalingam ◽  
Subramaniam Sundaramahalingam ◽  
Rajendran Rajaram
Keyword(s):  
Cell Wall ◽  
Mycobacterium Tuberculosis ◽  
Titanium Oxide ◽  
Metabolic Activity ◽  
Biofilm Formation ◽  
Antimycobacterial Activity ◽  
Oxide Nanoparticles ◽  
Antibiofilm Activity ◽  
Titanium Oxide Nanoparticles ◽  
Size Dependent

The titanium oxide nanoparticles showed excellent antibiofilm activity against Mycobacterium tuberculosis by inhibiting the colony formation and damage the cell wall leads to immature biofilm formation as well as inhibition of metabolic activity.

Titanium Oxide Nanoparticles Improve the Chemotherapeutic Action of Erlotinib in Liver Cancer Cells

2020 ◽  
Vol 16 (4) ◽  
pp. 337-343
Author(s):  
Shaimaa E. Abdel-Ghany ◽  
Eman El-Sayed ◽  
Nour Ashraf ◽  
Nada Mokhtar ◽  
Amany Alqosaibi ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Titanium Oxide ◽  
Phase Distribution ◽  
Oxide Nanoparticles ◽  
Titanium Oxide Nanoparticles ◽  
Liver Cancer Cells ◽  
M Phase ◽  
Apoptosis Detection ◽  
Novel Method

Background: Hepatocellular carcinoma is the second leading cause of cancer-related deaths among other types of cancer due to lack of effective treatments and late diagnosis. Nanocarriers represent a novel method to deliver chemotherapeutic drugs, enhancing their bioavailability and stability. Methods: In the present study, we loaded gold nanoparticles (AuNPs) and titanium oxide nanoparticles (TiO2NPs) with ERL to investigate the efficiency of the formed composite in inducing apoptosis in HepG2 liver cancer cells. Cytotoxicity was assessed using MTT assay and cell phase distribution was assessed by flow cytometry along with apoptosis detection. Results: Data obtained indicated the efficiency of the formed composite to significantly induce cell death and arrest cell cycle and G2/M phase. IRF4 was downregulated after treatment with loaded ERL. Conclusion: Our data showed that loading ERL on TiO2NPs was more efficient than AuNPs. However, both nanocarriers were efficient compared with control.

Synthesis of polymorphic titanium oxide nanoparticles by a rapid gas-phase chemical reaction

2016 ◽  
Vol 26 (2) ◽  
pp. 157-159 ◽  
Author(s):  
Ning Luo ◽  
Hong Wen Jing ◽  
Zhan Guo Ma ◽  
Weidong Liu ◽  
Liangchi Zhang ◽  
...  
Keyword(s):  
Gas Phase ◽  
Titanium Oxide ◽  
Chemical Reaction ◽  
Oxide Nanoparticles ◽  
Titanium Oxide Nanoparticles ◽  
Phase Chemical
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