scholarly journals Sustained Biochemical Signaling and Contact Guidance by Electrospun Bicomponents as Promising Scaffolds for Nerve Tissue Regeneration

ACS Omega ◽  
2021 ◽  
Author(s):  
Chaoyu Liu ◽  
Zhiping Wang ◽  
Xumei Yao ◽  
Min Wang ◽  
Zhigang Huang ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Nerve Tissue ◽  
Contact Guidance

Amniotic Stem Cell-Conditioned Media for the Treatment of Nerve and Muscle Pathology: A Systematic Review

2021 ◽  
Author(s):  
Chukwuweike Gwam ◽  
Ahmed Emara ◽  
Nequesha Mohamed ◽  
Noor Chughtai ◽  
Johannes Plate ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Tissue Regeneration ◽  
Cell Damage ◽  
Conditioned Media ◽  
Nerve Tissue ◽  
Muscle Pathology ◽  
Loss Of Function ◽  
Cell Based Therapy

Muscle and nerve tissue damage can elicit a significant loss of function and poses as a burden for patients and healthcare providers. Even for tissues, such as the peripheral nerve and skeletal muscle, that harbor significant regenerative capacity, innate regenerative processes often lead to less than optimal recovery and residual loss of function. The reasons for poor regeneration include significant cell damage secondary to oxidative stress, poor recruitment of resident stem cells, and an unfavorable microenvironment for tissue regeneration. Stem cell-based therapy was once thought as a potential therapy in tissue regeneration, due to its self-renewal and multipotent capabilities. Early advocates for cellular-based therapy pointed to the pluripotent nature of stem cells, thus eluding to its ability to differentiate into resident cells as the source of its regenerative capability. However, increasing evidence has revealed a lack of engraftment and differentiation of stem cells, thereby pointing to stem cell paracrine activity as being responsible for its regenerative potential. Stem cell-conditioned media houses biomolecular factors that portray significant regenerative potential. Amniotic-derived stem cell-conditioned media (AFS-CM) has been of particular interest because of its ease of allocation and in vitro culture. The purpose of this review is to report the results of studies that assess the role of AFS-CM for nerve and muscle conditions. In this review, we will cover the effects of AFS-CM on cellular pathways, genes, and protein expression for different nerve and muscle cell types.

Controlled degradable chitosan/collagen composite scaffolds for application in nerve tissue regeneration

2019 ◽  
Vol 166 ◽  
pp. 73-85 ◽  
Author(s):  
Junzeng Si ◽  
Yanhong Yang ◽  
Xiaoling Xing ◽  
Feng Yang ◽  
Peiyan Shan
Keyword(s):  
Tissue Regeneration ◽  
Nerve Tissue ◽  
Composite Scaffolds

scholarly journals Application of Stem Cells and Advanced Materials in Nerve Tissue Regeneration

2018 ◽  
Vol 2018 ◽  
pp. 1-2 ◽  
Author(s):  
Huaqiong Li ◽  
Adam Qingsong Ye ◽  
Ming Su
Keyword(s):  
Stem Cells ◽  
Tissue Regeneration ◽  
Advanced Materials ◽  
Nerve Tissue

scholarly journals Sacrificial Crystal Templated Hyaluronic Acid Hydrogels As Biomimetic 3D Tissue Scaffolds for Nerve Tissue Regeneration

2017 ◽  
Vol 3 (7) ◽  
pp. 1451-1459 ◽  
Author(s):  
Richelle C. Thomas ◽  
Philip Vu ◽  
Shan P. Modi ◽  
Paul E. Chung ◽  
R. Clive Landis ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Tissue Regeneration ◽  
Tissue Scaffolds ◽  
Nerve Tissue

Nerve tissue regeneration

2011 ◽  
pp. 168-201 ◽  
Author(s):  
C. Wang ◽  
H. Koh ◽  
S. Ramakrishna ◽  
S. Liao
Keyword(s):  
Tissue Regeneration ◽  
Nerve Tissue
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