scholarly journals Critical Insight into Plausible Acquired Tocopherol Pathway in Neglected Human Trypanosomatids

ACS Omega ◽  
2021 ◽  
Author(s):  
Santanu Sasidharan ◽  
Timir Tripathi ◽  
Prakash Saudagar
Keyword(s):  
Critical Insight ◽  
Insight Into

Importance of the Intersection of Library and Information Sciences with Systems Theory

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Hannah Lee
Keyword(s):  
System Theory ◽  
General System ◽  
General System Theory ◽  
Von Bertalanffy ◽  
Meta Level ◽  
Professional Field ◽  
The Subject ◽  
Critical Insight ◽  
Insight Into ◽  
Information Sciences

This paper is the attempt to show how system theory could provide critical insight into the transdisciplinary field of library and information sciences (LIS). It begins with a discussion on the categorization of library and information sciences as an academic and professional field (or rather, the lack of evidence on the subject) and what is exactly meant by system theory, drawing upon the general system theory established by Ludwig von Bertalanffy. The main conversation of this paper focuses on the inadequacies of current meta-level discussions of LIS and the benefits of general system theory (particularly when considering the exponential rapidity in which information travels) with LIS.

Intimacy as Transgression and the Problem of Freedom

2018 ◽  
Vol 1 (1) ◽  
pp. 18
Author(s):  
Kym Maclaren
Keyword(s):  
Intimate Relationships ◽  
Critical Analysis ◽  
Mutual Recognition ◽  
Public Institutions ◽  
The Other ◽  
Social Forces ◽  
Critical Insight ◽  
Insight Into ◽  
What Matters

“To consent to love or be loved,” said Merleau-Ponty, “is to consent also to influence someone else, to decide to a certain extent on behalf of the other.” This essay explicates that idea through a meditation on intimacy. I propose, first, that, on Merleau-Ponty’s account, we are always transgressing into each other’s experience, whether we are strangers or familiars; I call this “ontological intimacy.” Concrete experiences of intimacy are based upon this ontological intimacy, and can take place at two levels: (1) at-this-moment (such that we can experience intimacy even with strangers, by sharing a momentary but extra-ordinary mutual recognition) and (2) in shared interpersonal institutions, or habitual, enduring, and co-enacted visions of who we are, how to live, and what matters. Through particular examples of dynamics within these layers of intimacy (drawing upon work by Berne and by Russon), I claim that we are always, inevitably, imposing an “unfreedom” upon our intimate others. Freedom, then, can only develop from within and by virtue of this “unfreedom.” Thus, what distinguishes empowering or emancipating relationships from oppressive ones is not the removal of transgressive normative social forces; it is rather the particular character of those transgressive forces. Some transgressions upon others’ experience—some forms of “unfreedom”—will tend to promote freedom; others will tend to hinder it. This amounts to a call for promoting agency and freedom not only through critical analysis of public institutions, practices and discourses, but also through critical insight into and transformation of our most private and intimate relationships.

Critical Insight into the Attributes of Emerging Novel Coronavirus (COVID-19) in India and Across the World

Coronaviruses ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 49-56
Author(s):  
Gaurav M. Doshi ◽  
Hemen S. Ved ◽  
Ami P. Thakkar
Keyword(s):  
Review Article ◽  
World Health ◽  
Effective Vaccine ◽  
Human Contact ◽  
The World ◽  
Critical Insight ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Insight Into ◽  
Old Drugs

The World Health Organization (WHO) has recently announced the spread of novel coronavirus (nCoV) globally and has declared it a pandemic. The probable source of transmission of the virus, which is from animal to human and human to human contact, has been established. As per the statistics reported by the WHO on 11th April 2020, data has shown that more than sixteen lakh confirmed cases have been identified globally. The reported cases related to nCoV in India have been rising substantially. The review article discusses the characteristics of nCoV in detail with the probability of potentially effective old drugs that may inhibit the virus. The research may further emphasize and draw the attention of the world towards the development of an effective vaccine as well as alternative therapies. Moreover, the article will help to bridge the gap between the new researchers since it’s the current thrust area of research.

scholarly journals Lessons from the study of plant mating systems for exploring the causes and consequences of inbreeding in marine invertebrates

2021 ◽  
Vol 168 (3) ◽  
Author(s):  
Kevin C. Olsen ◽  
Will H. Ryan ◽  
Ellen T. Kosman ◽  
Jose A. Moscoso ◽  
Don R. Levitan ◽  
...  
Keyword(s):  
Mating Systems ◽  
Marine Invertebrates ◽  
Reproductive Traits ◽  
Theory And Practice ◽  
Costs And Benefits ◽  
Life History Variation ◽  
Invertebrate Animals ◽  
Plant Mating Systems ◽  
Critical Insight ◽  
Insight Into

AbstractMany benthic marine invertebrates resemble plants in being modular and either sessile or sedentary, and by relying on an external vector to disperse their gametes. These shared features, along with recent evidence of inbreeding in these taxa, suggest that theory and practice bearing on the evolutionary costs and benefits of inbreeding for plants could advance our understanding of the ecology and evolution of invertebrate animals. We describe how the theory for the evolution of inbreeding and outbreeding could apply to benthic invertebrates, identify and compare techniques used to quantify inbreeding in plants and animals, translate relevant botanical concepts and empirical patterns to their zoological equivalents, and articulate predictions for how inbreeding might be associated with major axes of variation in sessile and sedentary marine invertebrates. The theory of inbreeding and outbreeding provides critical insight into major patterns of life-history variation in plants and holds similar promise as a complementary perspective on the evolution of reproductive traits, lifespan, ecological strategies, and dispersal in marine invertebrates. Extending what we have learned from plants to marine invertebrates promises to broaden the general study of mating systems.

scholarly journals Human immunity against EBV—lessons from the clinic

2017 ◽  
Vol 214 (2) ◽  
pp. 269-283 ◽  
Author(s):  
Stuart G. Tangye ◽  
Umaimainthan Palendira ◽  
Emily S.J. Edwards
Keyword(s):  
Immune Cell ◽  
Underlying Disease ◽  
Lymphoproliferative Disease ◽  
Barr Virus ◽  
Ebv Infection ◽  
Human Immunity ◽  
Critical Insight ◽  
Epstein Barr ◽  
Mammalian Immune System ◽  
Insight Into

The mammalian immune system has evolved over many millennia to be best equipped to protect the host from pathogen infection. In many cases, host and pathogen have coevolved, each acquiring sophisticated ways of inducing or protecting from disease. Epstein-Barr virus (EBV) is a human herpes virus that infects >90% of individuals. Despite its ubiquity, infection by EBV is often subclinical; this invariably reflects the necessity of the virus to preserve its host, balanced with sophisticated host immune mechanisms that maintain viral latency. However, EBV infection can result in various, and often fatal, clinical sequelae, including fulminant infectious mononucleosis, hemophagocytic lymphohistiocytosis, lymphoproliferative disease, organomegaly, and/or malignancy. Such clinical outcomes are typically observed in immunosuppressed individuals, with the most extreme cases being Mendelian primary immunodeficiencies (PIDs). Although these conditions are rare, they have provided critical insight into the cellular, biochemical, and molecular requirements for robust and long-lasting immunity against EBV infection. Here, we review the virology of EBV, mechanisms underlying disease pathogenesis in PIDs, and developments in immune cell–mediated therapy to treat disorders associated with or induced by EBV infection.

Grave Visions: Visual Experience and Adaptation

2021 ◽  
Author(s):  
Richard David Evan
Keyword(s):  
Visual Experience ◽  
Point Of View ◽  
Early Cinema ◽  
Gothic Novel ◽  
Francis Ford Coppola ◽  
Mise En Scene ◽  
Critical Insight ◽  
The Spectator ◽  
The Look ◽  
Insight Into

Rather than approaching the ‘look’ of adaptation through point of view or the ‘vision’ of the adapter, this chapter examines the material, visible texture of screen adaptation. Using two adaptations of Bram Stoker’s gothic novel Dracula, I analyse how each uses mise en scène, cinematography, and editing to thicken and make tangible Stoker’s questioning of the reliability of vision in modernity. The first, Nosferatu (F.W Murnau, 1922) employs the tricks of early cinema to shock spectators, while the second—Bram Stoker’s Dracula (Francis Ford Coppola, 1992)—uses a neo-baroque aesthetic that ruptures the screen and engulfs the spectator, much like one of Dracula’s victims. This chapter suggests that critical insight into an adaptation can be found quite literally in sight, and embraces how the materiality of adaptation overlaps with the materiality of vision.

A critical insight into the effectiveness of research methods evolved to secure IoT ecosystem

2019 ◽  
Vol 11 (4/5) ◽  
pp. 332
Author(s):  
Burhan Ul Islam Khan ◽  
Rashidah Funke Olanrewaju ◽  
Farhat Anwar ◽  
Roohie Naaz Mir ◽  
Athaur Rahman Najeeb
Keyword(s):  
Research Methods ◽  
Critical Insight ◽  
Insight Into

Critical Discourse Analysis of Adjectives Used with the Word Multiculturalism in British Print Media

2016 ◽  
Vol 8 (6) ◽  
pp. 185
Author(s):  
Sadok Abcha
Keyword(s):  
Discourse Analysis ◽  
Critical Discourse Analysis ◽  
Print Media ◽  
Theoretical Framework ◽  
Critical Discourse ◽  
Key Word ◽  
Critical Insight ◽  
The Times ◽  
The Right ◽  
Insight Into

The present paper critically analyses the ideological uses of the adjectives used to describe multiculturalism in opinion articles published by two British quality newspapers, The Telegraph and The Times, which politically lean to The Right. Methodologically, the sample on which this study is based has been retrieved from the websites of the two dailies by means of the Key Word In Context (KWIC) technique, which has been used to look for comment articles published between July 2005 and December 2015, and in which the search word, multiculturalism used with an adjective featured. Using Fairclough’s theoretical framework of Critical Discourse Analysis (CDA), the study pinpoints the ideological underpinnings of the adjectives used with the word multiculturalism in the editorials. The study found out that all the adjectives are used in a derogative way to describe multiculturalism as being unreasonable, harmful and unsuccessful. Significantly, this paper provides critical insight into the peculiar uses of derogative adjectives in comment articles dealing with multiculturalism and avers that negative adjectives are not simply linguistic elements, but most importantly, ideological tools.

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