scholarly journals Long-Range Surface Plasmon Resonance Configuration for Enhancing SERS with an Adjustable Refractive Index Sample Buffer to Maintain the Symmetry Condition

ACS Omega ◽  
2020 ◽  
Vol 5 (51) ◽  
pp. 32951-32958
Author(s):  
Yu Liu ◽  
Haitao Zhang ◽  
Yijia Geng ◽  
Shuping Xu ◽  
Weiqing Xu ◽  
...  
2020 ◽  
Vol 168 ◽  
pp. 112508
Author(s):  
Surbhi Jain ◽  
Ayushi Paliwal ◽  
Vinay Gupta ◽  
Monika Tomar

2021 ◽  
Vol 61 ◽  
pp. 102449
Author(s):  
Rozalina Zakaria ◽  
NurAina'a Mardhiah Zainuddin ◽  
Muhammad Aiman Saufi Ahmad Fahri ◽  
Punithavathi M. Thirunavakkarasu ◽  
Shobhit K. Patel ◽  
...  

Photonics ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 379
Author(s):  
Wenyi Bu ◽  
Zhifang Wu ◽  
Perry Ping Shum ◽  
Xuguang Shao ◽  
Jixiong Pu

Long-range surface plasmon resonance (LRSPR), generated from a coupled plasmon polariton in a thin metal slab sandwiched by two dielectrics, has attracted more and more attention due to its merits, such as longer propagation and deeper penetration than conventional single-interface surface plasmon resonance. Many useful applications related to light–medium interaction have been demonstrated based on the LRSPR effect, especially in the sensing area. Here, we propose and demonstrate an LRSPR-based refractive index sensor by using a SiO2-Au-TiO2 heterostructure, in which a D-shaped honeycomb-microstructure optical fiber (MOF) is designed as the silica substrate and then deposited with a gold film and thin-layer titanium dioxide (TiO2). By using the full-vector finite-element method (FEM), this heterostructure is numerically investigated and demonstrated to excite LRSPR without a buffer layer, which is usually necessary in previous LRSPR devices. Through comprehensive discussion about the influence of structural parameters on the resonant wavelength, the excitation of the LRSPR in the proposed heterostructure is revealed to be highly related to the effective refractive index of MOF’s fundamental core mode, which is mainly determined by the MOF’s pitch, the thicknesses of the silica web and the planar-layer silica. Moreover, the thin-layer TiO2 plays an important role in significantly enhancing the resonance and the sensitivity to analyte’s refractive index as well, when it is coated on the top of the Au film rather than between the metal and waveguide. Finally, the proposed LRSPR sensor based on SiO2-Au-TiO2 heterostructure shows an ultra-high wavelength sensitivity of 20,100 nm/RIU and the corresponding minimum resolution is as low as 4.98×10−7 RIU. Thus, the proposed LRSPR device offers considerable potential for sensing applications in biomedical and biochemical areas.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Wanida Tangkawsakul ◽  
Toemsak Srikhirin ◽  
Kazunari Shinbo ◽  
Keizo Kato ◽  
Futao Kaneko ◽  
...  

In this study, we demonstrate a long-range surface plasmon resonance (LR-SPR) biosensor for the detection of whole cell by captured antigens A and B on the surface of red blood cells (RBCs) as a model. The LR-SPR sensor chip consists of high-refractive index glass, a Cytop film layer, and a thin gold (Au) film, which makes the evanescent field intensity and the penetration depth longer than conventional SPR. Therefore, the LR-SPR biosensor has improved capability for detecting large analytes, such as RBCs. The antibodies specific to blood group A and group B (Anti-A and Anti-B) are covalently immobilized on a grafting self-assembled monolayer (SAM)/Au surface on the biosensor. For blood typing, RBC samples can be detected by the LR-SPR biosensor through a change in the refractive index. We determined that the results of blood typing using the LR-SPR biosensor are consistent with the results obtained from the agglutination test. We obtained the lowest detection limits of 1.58 × 105 cells/ml for RBC-A and 3.83 × 105 cells/ml for RBC-B, indicating that the LR-SPR chip has a higher sensitivity than conventional SPR biosensors (3.3 × 108 cells/ml). The surface of the biosensor can be efficiently regenerated using 20 mM NaOH. In summary, as the LR-SPR technique is sensitive and has a simple experimental setup, it can easily be applied for ABO blood group typing.


Photonics ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 41
Author(s):  
Najat Andam ◽  
Siham Refki ◽  
Hidekazu Ishitobi ◽  
Yasushi Inouye ◽  
Zouheir Sekkat

The determination of optical constants (i.e., real and imaginary parts of the complex refractive index (nc) and thickness (d)) of ultrathin films is often required in photonics. It may be done by using, for example, surface plasmon resonance (SPR) spectroscopy combined with either profilometry or atomic force microscopy (AFM). SPR yields the optical thickness (i.e., the product of nc and d) of the film, while profilometry and AFM yield its thickness, thereby allowing for the separate determination of nc and d. In this paper, we use SPR and profilometry to determine the complex refractive index of very thin (i.e., 58 nm) films of dye-doped polymers at different dye/polymer concentrations (a feature which constitutes the originality of this work), and we compare the SPR results with those obtained by using spectroscopic ellipsometry measurements performed on the same samples. To determine the optical properties of our film samples by ellipsometry, we used, for the theoretical fits to experimental data, Bruggeman’s effective medium model for the dye/polymer, assumed as a composite material, and the Lorentz model for dye absorption. We found an excellent agreement between the results obtained by SPR and ellipsometry, confirming that SPR is appropriate for measuring the optical properties of very thin coatings at a single light frequency, given that it is simpler in operation and data analysis than spectroscopic ellipsometry.


Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1728
Author(s):  
Joshua Fernandes ◽  
Sangmo Kang

The near-field enhancement and localized surface plasmon resonance (LSPR) on the core-shell noble metal nanostructure surfaces are widely studied for various biomedical applications. However, the study of the optical properties of new plasmonic non-spherical nanostructures is less explored. This numerical study quantifies the optical properties of spherical and non-spherical (prolate and oblate) dimer nanostructures by introducing finite element modelling in COMSOL Multiphysics. The surface plasmon resonance peaks of gold nanostructures should be understood and controlled for use in biological applications such as photothermal therapy and drug delivery. In this study, we find that non-spherical prolate and oblate gold dimers give excellent tunability in a wide range of biological windows. The electromagnetic field enhancement and surface plasmon resonance peak can be tuned by varying the aspect ratio of non-spherical nanostructures, the refractive index of the surrounding medium, shell thickness, and the distance of separation between nanostructures. The absorption spectra exhibit considerably greater dependency on the aspect ratio and refractive index than the shell thickness and separation distance. These results may be essential for applying the spherical and non-spherical nanostructures to various absorption-based applications.


Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4348
Author(s):  
Piotr Mrozek ◽  
Ewa Gorodkiewicz ◽  
Paweł Falkowski ◽  
Bogusław Hościło

Comparative analysis of the sensitivity of two surface plasmon resonance (SPR) biosensors was conducted on a single-metallic Au sensor and bimetallic Ag–Au sensor, using a cathepsin S sensor as an example. Numerically modeled resonance curves of Au and Ag–Au layers, with parameters verified by the results of experimental reflectance measurement of real-life systems, were used for the analysis of these sensors. Mutual relationships were determined between ∂Y/∂n components of sensitivity of the Y signal in the SPR measurement to change the refractive index n of the near-surface sensing layer and ∂n/∂c sensitivity of refractive index n to change the analyte’s concentration, c, for both types of sensors. Obtained results were related to experimentally determined calibration curves of both sensors. A characteristic feature arising from the comparison of calibration curves is the similar level of Au and Ag–Au biosensors’ sensitivity in the linear range, where the signal of the AgAu sensor is at a level several times greater. It was shown that the influence of sensing surface morphology on the ∂n/∂c sensitivity component had to be incorporated to explain the features of calibration curves of sensors. The shape of the sensory surface relief was proposed to increase the sensor sensitivity at low analyte concentrations.


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