scholarly journals Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line

ACS Omega ◽  
2020 ◽  
Vol 5 (27) ◽  
pp. 16796-16810
Author(s):  
Kenneth Hodge ◽  
Jiradej Makjaroen ◽  
Jonathan Robinson ◽  
Sakda Khoomrung ◽  
Trairak Pisitkun
Blood ◽  
1987 ◽  
Vol 70 (6) ◽  
pp. 1904-1909
Author(s):  
OJ Nielsen ◽  
SJ Schuster ◽  
R Kaufman ◽  
AJ Erslev ◽  
J Caro

Production of immuno and biologically active erythropoietin was documented to occur in the human hepatoblastoma cell line HepG-2. The expression of the erythropoietin gene was further verified by Northern blot analysis using a single stranded RNA probe. In vitro studies showed that erythropoietin production by these cells was not stimulated by hypoxia or cobalt chloride, but was related to the proliferative activity of the cells in culture. In addition it was found that the secretion of erythropoietin was almost completely abrogated by tunicamycin, an inhibitor of N-linked glycosylation. This effect of tunicamycin was also observed in a permanently transfected cell line that secretes erythropoietin in large quantities.


1993 ◽  
Vol 1157 (1) ◽  
pp. 114-118 ◽  
Author(s):  
Paul G.J. van Stralen ◽  
Hans J. van der Hoek ◽  
Roel Docter ◽  
Marion de Jong ◽  
Eric P. Krenning ◽  
...  

2005 ◽  
Vol 40 (4) ◽  
pp. 653-657 ◽  
Author(s):  
Steven W. Warmann ◽  
Jörg Fuchs ◽  
Guido Seitz ◽  
Peter Ruck ◽  
Claudia Treuner ◽  
...  

1995 ◽  
Vol 23 (4) ◽  
pp. 431-439 ◽  
Author(s):  
Romain Moirand ◽  
Franck Kerdavid ◽  
Olivier Loréal ◽  
Noëlla Hubert ◽  
Patricia Leroyer ◽  
...  

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