Rapid Identification by Surface-Enhanced Raman Spectroscopy of Cancer Cells at Low Concentrations Flowing in a Microfluidic Channel

ACS Nano ◽  
2015 ◽  
Vol 9 (4) ◽  
pp. 4328-4336 ◽  
Author(s):  
Alessia Pallaoro ◽  
Mehran R. Hoonejani ◽  
Gary B. Braun ◽  
Carl D. Meinhart ◽  
Martin Moskovits
Keyword(s):  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Microfluidic Channel ◽  
Surface Enhanced Raman Spectroscopy ◽  
Rapid Identification ◽  
Low Concentrations ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Uptake of silver nanoparticles by DHA-treated cancer cells examined by surface-enhanced Raman spectroscopy in a microfluidic chip

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1306-1313 ◽  
Author(s):  
Zhimin Zhai ◽  
Fengqiu Zhang ◽  
Xiangyu Chen ◽  
Jie Zhong ◽  
Gang Liu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Living Cells ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This paper reports on the synthesis and application of biocompatible and sensitive SERS nanoparticles for the study of uptake of nanoparticles into living cells in a microfluidic chip through surface-enhanced Raman spectroscopy (SERS).

Ultra-sensitive trace analysis of cyanide water pollutant in a PDMS microfluidic channel using surface-enhanced Raman spectroscopy

The Analyst ◽  
2005 ◽  
Vol 130 (7) ◽  
pp. 1009 ◽  
Author(s):  
Kwon-hae Yea ◽  
Sangyeop Lee ◽  
Jin Burm Kyong ◽  
Jaebum Choo ◽  
Eun Kyu Lee ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Trace Analysis ◽  
Microfluidic Channel ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Water Pollutant

scholarly journals Detection of Alternative Drugs for Illegal Injection Based on Surface-Enhanced Raman Spectroscopy

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Lin Bao ◽  
Siqingaowa Han ◽  
Xuanyu Sha ◽  
Hang Zhao ◽  
Yuping Liu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Density Functional ◽  
Surface Enhanced Raman Spectroscopy ◽  
Rapid Identification ◽  
Heroin Addiction ◽  
Sers Substrate ◽  
Functional Theory ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
And Control

Promethazine and scopolamine are two major components of a drug commonly used as a substitute for heroin addiction but with its own potential for abuse. Here, surface-enhanced Raman spectroscopy experiments were combined with density functional theory computations of the Raman frequencies of promethazine. The enhancement of the SERS substrate was optimized by contrast detection of silver nanoparticles. The optimized substrate was used to detect scopolamine, promethazine and their mixtures. Several mixtures of different concentrations were detected and analyzed. The approach of rapid identification and monitoring of drugs will become an important tool in the detection and control of illicit drug use.

Branched gold nanoparticles on ZnO 3D architecture as biomedical SERS sensors

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93644-93651 ◽  
Author(s):  
S. Picciolini ◽  
N. Castagnetti ◽  
R. Vanna ◽  
D. Mehn ◽  
M. Bedoni ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Biomedical Application ◽  
Surface Enhanced Raman Spectroscopy ◽  
Drug Detection ◽  
3D Surface ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
3D Architecture

We present a new 3D surface-enhanced Raman spectroscopy substrate made of branched gold nanoparticles supported on ZnO tetrapods that was proved to be effective in different biomedical application such as drug detection and cancer cells analysis.

Silicon Substrate Microelectrode Array for Surface-Enhanced Raman Spectroscopy

1995 ◽  
Vol 49 (12) ◽  
pp. 1793-1795 ◽  
Author(s):  
Valentin R. Zhelyaskov ◽  
Elizabeth T. Milne ◽  
Jamille F. Hetke ◽  
Michael D. Morris
Keyword(s):  
Raman Spectroscopy ◽  
Silicon Substrate ◽  
Laser Power ◽  
Counter Electrode ◽  
Microelectrode Array ◽  
Surface Enhanced Raman Spectroscopy ◽  
Standard Procedures ◽  
Low Concentrations ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Electrode sites of a photolithographically fabricated microelectrode array have been demonstrated to function as surface-enhanced Raman Spectroscopy (SERS) microelectrodes. The 5 × 15 μm iridium electrodes on the substrate are electroplated with silver and activated by standard procedures. Working and counter-electrode functions are integrated onto the same assembly. The electrode is shown to yield adenosine and pyridine spectra at low concentrations and submilliwatt laser power.

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