Self-Guiding Polymeric Prodrug Micelles with Two Aggregation-Induced Emission Photosensitizers for Enhanced Chemo-Photodynamic Therapy

Xiaoqing Yi; Jing-Jing Hu; Jun Dai; Xiaoding Lou; Zujin Zhao; Fan Xia; Ben Zhong Tang

doi:10.1021/acsnano.0c09407

Self-Guiding Polymeric Prodrug Micelles with Two Aggregation-Induced Emission Photosensitizers for Enhanced Chemo-Photodynamic Therapy

ACS Nano ◽

10.1021/acsnano.0c09407 ◽

2021 ◽

Vol 15 (2) ◽

pp. 3026-3037

Author(s):

Xiaoqing Yi ◽

Jing-Jing Hu ◽

Jun Dai ◽

Xiaoding Lou ◽

Zujin Zhao ◽

...

Keyword(s):

Photodynamic Therapy ◽

Aggregation Induced Emission ◽

Polymeric Prodrug

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Good Steel Used in the Blade: Well‐Tailored Type‐I Photosensitizers with Aggregation‐Induced Emission Characteristics for Precise Nuclear Targeting Photodynamic Therapy

Advanced Science ◽

10.1002/advs.202100524 ◽

2021 ◽

pp. 2100524

Author(s):

Miaomiao Kang ◽

Zhijun Zhang ◽

Wenhan Xu ◽

Haifei Wen ◽

Wei Zhu ◽

...

Keyword(s):

Photodynamic Therapy ◽

Emission Characteristics ◽

Type I ◽

Nuclear Targeting ◽

Aggregation Induced Emission

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A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

Biomaterials Science ◽

10.1039/d0bm02099k ◽

2021 ◽

Vol 9 (4) ◽

pp. 1232-1236

Author(s):

Yujie Zhang ◽

Wendi Huang ◽

Xueying Tan ◽

Jinhui Wang ◽

Yufen Zhao ◽

...

Keyword(s):

Photodynamic Therapy ◽

Aggregation Induced Emission ◽

Dual Functional

A mitochondria-targeted dual-functional aggregation-induced emission luminogen, TPP-TPEDCH, was rationally designed and developed for intracellular mitochondrial imaging and photodynamic therapy.

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Biomineralization of Aggregation-Induced Emission-Active Photosensitizers for pH-Mediated Tumor Imaging and Photodynamic Therapy

ACS Applied Bio Materials ◽

10.1021/acsabm.1c00298 ◽

2021 ◽

Author(s):

Wei Liu ◽

Zuhao Li ◽

Yanqing Qiu ◽

Jun Li ◽

Jinfeng Yang ◽

...

Keyword(s):

Photodynamic Therapy ◽

Tumor Imaging ◽

Aggregation Induced Emission

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Multifunctional aggregation-induced emission nanoparticle for high-fidelity imaging of lipid droplets in living cells and its application in photodynamic therapy

Chemical Engineering Journal ◽

10.1016/j.cej.2020.128186 ◽

2020 ◽

pp. 128186

Author(s):

Yanpeng Dai ◽

Xinxin Zhao ◽

Hefang Ji ◽

Dongdong Zhang ◽

Pan Zhang ◽

...

Keyword(s):

Photodynamic Therapy ◽

Lipid Droplets ◽

Living Cells ◽

High Fidelity ◽

Aggregation Induced Emission

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A high therapeutic efficacy of polymeric prodrug nano-assembly for a combination of photodynamic therapy and chemotherapy

Communications Biology ◽

10.1038/s42003-018-0204-6 ◽

2018 ◽

Vol 1 (1) ◽

Cited By ~ 27

Author(s):

Xiaoqing Yi ◽

Jun Dai ◽

Yingyan Han ◽

Min Xu ◽

Xiaojin Zhang ◽

...

Keyword(s):

Photodynamic Therapy ◽

Therapeutic Efficacy ◽

Polymeric Prodrug

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Targeted Photodynamic Therapy using a Water-Soluble Aggregation-Induced Emission Photosensitizer Activated by an Acidic Tumor Microenvironment

Chemical Engineering Journal ◽

10.1016/j.cej.2021.134327 ◽

2021 ◽

pp. 134327

Author(s):

Xuehong Min ◽

Fan Yi ◽

Xiao-Le Han ◽

Ming Li ◽

Qianci Gao ◽

...

Keyword(s):

Photodynamic Therapy ◽

Tumor Microenvironment ◽

Water Soluble ◽

Aggregation Induced Emission ◽

Targeted Photodynamic Therapy

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Mitochondrion‐Anchored Photosensitizer with Near Infrared‐I Aggregation‐Induced Emission for Near Infrared‐II Two‐Photon Photodynamic Therapy

Advanced Healthcare Materials ◽

10.1002/adhm.202101056 ◽

2021 ◽

pp. 2101056

Author(s):

Zhenyan He ◽

Yuting Gao ◽

Huimin Zhang ◽

Ying Xue ◽

Fanling Meng ◽

...

Keyword(s):

Photodynamic Therapy ◽

Near Infrared ◽

Aggregation Induced Emission ◽

Two Photon

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Aggregation‐Induced Emission Gold Clustoluminogens for Enhanced Low‐Dose X‐ray‐Induced Photodynamic Therapy

Angewandte Chemie International Edition ◽

10.1002/anie.201908712 ◽

2019 ◽

Vol 59 (25) ◽

pp. 9914-9921 ◽

Cited By ~ 12

Author(s):

Wenjing Sun ◽

Li Luo ◽

Yushuo Feng ◽

Yuting Cai ◽

Yixi Zhuang ◽

...

Keyword(s):

Photodynamic Therapy ◽

Low Dose ◽

Aggregation Induced Emission ◽

X Ray

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Tumor‐Exocytosed Exosome/Aggregation‐Induced Emission Luminogen Hybrid Nanovesicles Facilitate Efficient Tumor Penetration and Photodynamic Therapy

Angewandte Chemie ◽

10.1002/ange.202003672 ◽

2020 ◽

Vol 132 (33) ◽

pp. 13940-13947 ◽

Cited By ~ 1

Author(s):

Daoming Zhu ◽

Yanhong Duo ◽

Meng Suo ◽

Yonghua Zhao ◽

Ligang Xia ◽

...

Keyword(s):

Photodynamic Therapy ◽

Aggregation Induced Emission ◽

Tumor Penetration

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Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy

Chemical Communications ◽

10.1039/c5cc07818k ◽

2016 ◽

Vol 52 (13) ◽

pp. 2752-2755 ◽

Cited By ~ 59

Author(s):

Guorui Jin ◽

Guangxue Feng ◽

Wei Qin ◽

Ben Zhong Tang ◽

Bin Liu ◽

...

Keyword(s):

Photodynamic Therapy ◽

Rna Interference ◽

Organic Nanoparticles ◽

Aggregation Induced Emission ◽

Targeted Photodynamic Therapy

We report the design of AIE fluorogen (AIEgen)-based multifunctional organic nanoparticles with surface siRNA decoration for targeted photodynamic therapy and RNA interference therapy.

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