Scaling Laws in the Diffusive Release of Neutral Cargo from Hollow Hydrogel Nanoparticles: Paclitaxel-Loaded Poly(4-vinylpyridine)

ACS Nano ◽  
2020 ◽  
Vol 14 (11) ◽  
pp. 15227-15240
Author(s):  
Arturo Moncho-Jordá ◽  
Ana B. Jódar-Reyes ◽  
Matej Kanduč ◽  
Alicia Germán-Bellod ◽  
Juan M. López-Romero ◽  
...  
Keyword(s):  
Scaling Laws ◽  
Hydrogel Nanoparticles ◽  
Diffusive Release

Siphon Flows in Stratified Coronal Loops

1994 ◽  
Vol 144 ◽  
pp. 185-187
Author(s):  
S. Orlando ◽  
G. Peres ◽  
S. Serio
Keyword(s):  
Heat Flux ◽  
Scaling Laws ◽  
Flow Model ◽  
Supersonic Flows ◽  
Coronal Loops ◽  
Characteristic Parameters

AbstractWe have developed a detailed siphon flow model for coronal loops. We find scaling laws relating the characteristic parameters of the loop, explore systematically the space of solutions and show that supersonic flows are impossible for realistic values of heat flux at the base of the upflowing leg.

Equilibrium scaling laws for layered spin glasses

1993 ◽  
Vol 3 (10) ◽  
pp. 2041-2062 ◽  
Author(s):  
M. J. Thill ◽  
H. J. Hilhorst
Keyword(s):  
Spin Glasses ◽  
Scaling Laws ◽  
Layered Spin

Analysis of shear bands in slow granular flows using a frictional Cosserat model

2000 ◽  
Vol 627 ◽  
Author(s):  
Prabhu R. Nott ◽  
K. Kesava Rao ◽  
L. Srinivasa Mohan
Keyword(s):  
Scaling Laws ◽  
Shear Bands ◽  
Shear Layers ◽  
Theoretical Description ◽  
Field Variable ◽  
Cosserat Continuum ◽  
Momentum Balance ◽  
Rigid Plastic ◽  
Independent Field ◽  
Cosserat Model

ABSTRACTThe slow flow of granular materials is often marked by the existence of narrow shear layers, adjacent to large regions that suffer little or no deformation. This behaviour, in the regime where shear stress is generated primarily by the frictional interactions between grains, has so far eluded theoretical description. In this paper, we present a rigid-plastic frictional Cosserat model that captures thin shear layers by incorporating a microscopic length scale. We treat the granular medium as a Cosserat continuum, which allows the existence of localised couple stresses and, therefore, the possibility of an asymmetric stress tensor. In addition, the local rotation is an independent field variable and is not necessarily equal to the vorticity. The angular momentum balance, which is implicitly satisfied for a classical continuum, must now be solved in conjunction with the linear momentum balances. We extend the critical state model, used in soil plasticity, for a Cosserat continuum and obtain predictions for flow in plane and cylindrical Couette devices. The velocity profile predicted by our model is in qualitative agreement with available experimental data. In addition, our model can predict scaling laws for the shear layer thickness as a function of the Couette gap, which must be verified in future experiments. Most significantly, our model can determine the velocity field in viscometric flows, which classical plasticity-based model cannot.

Scaling laws of cylindrical shells under lateral pressure

AIAA Journal ◽  
1997 ◽  
Vol 35 ◽  
pp. 1669-1671
Author(s):  
A. Tabiei ◽  
J. Sun ◽  
G. J. Simitses
Keyword(s):  
Scaling Laws ◽  
Lateral Pressure ◽  
Cylindrical Shells

Chitosan-Based Hydrogel Nanoparticles for Cancer Therapy

2017 ◽  
Vol 7 (04) ◽  
Author(s):  
Azadi A. ◽  
Khazaei M. ◽  
Ashrafi H.
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Recent Decade ◽  
Reticuloendothelial System ◽  
Malignant Neoplasms ◽  
Mortality And Morbidity ◽  
Hydrogel Nanoparticles ◽  
Tissue Invasion ◽  
Causes Of Mortality ◽  
Nanoparticulate Systems

Cancer, an uncontrollable growth of cells, is among the leading causes of mortality and morbidity throughout the world. Malignant neoplasms are difficult to treat diseases because of their single in kind characteristics such as tissue invasion, metastasis, evading reticuloendothelial system (RES) and so forth. In recent decade polymeric nanoparticulate systems has gained special attention in drug delivery and targeting among all biocompatible nanoforms. Among these systems, chitosan-based hydrogel nanoparticles have been wildly utilized for drug delivery purposes. The usage of chitosan nanogels in cancer therapy significantly improved in recent years. The various cancers were the target of chitosan nanogels. Also, modification of other delivery systems with chitosan were much reported. The aim of this study is the review and update of the recent studies on chitosan nanogels applications in cancer therapy by focus on cancer based classification.

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