Enhanced Cancer DNA Vaccine via Direct Transfection to Host Dendritic Cells Recruited in Injectable Scaffolds

ACS Nano ◽  
2020 ◽  
Vol 14 (9) ◽  
pp. 11623-11636 ◽  
Author(s):  
Thanh Loc Nguyen ◽  
Yue Yin ◽  
Youngjin Choi ◽  
Ji Hoon Jeong ◽  
Jaeyun Kim
Keyword(s):  
Dendritic Cells ◽  
Dna Vaccine ◽  
Injectable Scaffolds

Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells

2016 ◽  
Vol 160 (4) ◽  
pp. 486-490 ◽  
Author(s):  
Zh. K. Nazarkina ◽  
M. V. Khar’kova ◽  
D. V. Antonets ◽  
E. S. Morozkin ◽  
S. I. Bazhan ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Breast Carcinoma ◽  
Dna Vaccine ◽  
Carcinoma Cells ◽  
Breast Carcinoma Cells

An adjuvant clinical trial of SCIB1, a DNA vaccine that targets dendritic cells in vivo, in fully resected melanoma patients.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 9035-9035
Author(s):  
Poulam M. Patel ◽  
Christian Ottensmeier ◽  
Clive Mulatero ◽  
Paul Lorigan ◽  
Ruth Plummer ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Dendritic Cells ◽  
Dna Vaccine ◽  
Melanoma Patients

scholarly journals Poly(2-aminoethyl methacrylate) with Well-Defined Chain Length for DNA Vaccine Delivery to Dendritic Cells

2011 ◽  
Vol 12 (12) ◽  
pp. 4373-4385 ◽  
Author(s):  
Weihang Ji ◽  
David Panus ◽  
R. Noelle Palumbo ◽  
Rupei Tang ◽  
Chun Wang
Keyword(s):  
Dendritic Cells ◽  
Chain Length ◽  
Dna Vaccine ◽  
Vaccine Delivery

scholarly journals Purified Malaria Pigment (Hemozoin) Enhances Dendritic Cell Maturation and Modulates the Isotype of Antibodies Induced by a DNA Vaccine

2002 ◽  
Vol 70 (7) ◽  
pp. 3939-3943 ◽  
Author(s):  
Cevayir Coban ◽  
Ken J. Ishii ◽  
David J. Sullivan ◽  
Nirbhay Kumar
Keyword(s):  
Dendritic Cells ◽  
Immune Responses ◽  
Dna Vaccine ◽  
Malaria Infection ◽  
Dendritic Cell Maturation ◽  
Antibody Responses ◽  
Cell Maturation ◽  
Myeloid Dendritic Cells ◽  
Malaria Pigment

ABSTRACT Hemozoin (malaria pigment) has been implicated in the modulation of immune responses during malaria infection. This study was designed to evaluate the effect of purified hemozoin on the in vitro activation of myeloid dendritic cells. Our study also revealed that in addition to enhancing the maturation of dendritic cells, hemozoin also greatly promotes immunoglobulin G2a antibody responses when coadministered with a DNA vaccine plasmid encoding Pfs25, a Plasmodium falciparum transmission-blocking antigen.

scholarly journals DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats

2013 ◽  
Vol 83 (2) ◽  
pp. 223-232 ◽  
Author(s):  
Ya Wang ◽  
Yuan Min Wang ◽  
Yiping Wang ◽  
Guoping Zheng ◽  
Geoff Yu Zhang ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dna Vaccine ◽  
Heymann Nephritis

Nucleofection of a DNA vaccine into human monocyte-derived dendritic cells

2012 ◽  
Vol 276 (1-2) ◽  
pp. 135-143
Author(s):  
Qiu Xie ◽  
Jia Luo ◽  
Zhiqiang Zhu ◽  
Guoliang Wang ◽  
Jianhua Wang ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dna Vaccine ◽  
Human Monocyte
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