Chemical Tools for the Study of Intramembrane Proteases

2015 ◽  
Vol 10 (11) ◽  
pp. 2423-2434 ◽  
Author(s):  
Minh T. N. Nguyen ◽  
Tim Van Kersavond ◽  
Steven H. L. Verhelst
Keyword(s):  
Intramembrane Proteases ◽  
Chemical Tools

Chemical tools for dissecting cell division

2021 ◽  
Author(s):  
Geng-Yuan Chen ◽  
Michael A. Lampson
Keyword(s):  
Cell Division ◽  
Chemical Tools

scholarly journals Glycan Microarrays as Chemical Tools for Identifying Glycan Recognition by Immune Proteins

2019 ◽  
Vol 7 ◽  
Author(s):  
Chao Gao ◽  
Mohui Wei ◽  
Tanya R. McKitrick ◽  
Alyssa M. McQuillan ◽  
Jamie Heimburg-Molinaro ◽  
...  
Keyword(s):  
Chemical Tools

Chemical Tools for Dissecting Bacterial Physiology and Virulence

Biochemistry ◽  
2009 ◽  
Vol 48 (37) ◽  
pp. 8776-8786 ◽  
Author(s):  
Sarah A. Stanley ◽  
Deborah T. Hung
Keyword(s):  
Bacterial Physiology ◽  
Chemical Tools

BIOCHEMISTRY: Intramembrane Proteases--Mixing Oil and Water

Science ◽  
2002 ◽  
Vol 296 (5576) ◽  
pp. 2156-2157 ◽  
Author(s):  
M. S. Wolfe
Keyword(s):  
Intramembrane Proteases

Small-molecule degraders of cyclin-dependent kinase protein: a review

2021 ◽  
Author(s):  
Bin Yu ◽  
Zekun Du ◽  
Yuming Zhang ◽  
Zhiyu Li ◽  
Jinlei Bian
Keyword(s):  
Cell Cycle ◽  
Drug Resistance ◽  
Protein Degradation ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Structural Characteristics ◽  
Protein A ◽  
Cyclin Dependent Kinase ◽  
Chemical Tools ◽  
Potential Therapeutics

Proteolysis-targeting chimeras are a new modality of chemical tools and potential therapeutics involving the induction of protein degradation. Cyclin-dependent kinase (CDK) protein, which is involved in cycles and transcription cycles, participates in regulation of the cell cycle, transcription and splicing. Proteolysis-targeting chimeras targeting CDKs show several advantages over traditional CDK small-molecule inhibitors in potency, selectivity and drug resistance. In addition, the discovery of molecule glues promotes the development of CDK degraders. Herein, the authors describe the existing CDK degraders and focus on the discussion of the structural characteristics and design of these degraders.

Ionic liquids as bioactive chemical tools for use in agriculture and the preservation of agricultural products

2018 ◽  
Vol 20 (21) ◽  
pp. 4764-4789 ◽  
Author(s):  
Adrian Zajac ◽  
Rafal Kukawka ◽  
Anna Pawlowska-Zygarowicz ◽  
Olga Stolarska ◽  
Marcin Smiglak
Keyword(s):  
Ionic Liquids ◽  
Recent Progress ◽  
Agricultural Products ◽  
Bioactive Components ◽  
Chemical Tools ◽  
Made In

The review presents the recent progress made in the field of ionic liquids bearing bioactive components, with a particular emphasis on their use as chemical tools in agriculture and the preservation of agricultural products.

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