Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin

2022 ◽  
Author(s):  
Yi-Chi Pan ◽  
Yung-Lin Wang ◽  
Shu-Ing Toh ◽  
Ning-Shian Hsu ◽  
Kuan-Hung Lin ◽  
...  
Keyword(s):  
Dual Mechanism

Therapeutic Targets for the Treatment of Comorbidities Associated with Epilepsy

2020 ◽  
Vol 13 (2) ◽  
pp. 85-93
Author(s):  
Kinjal Gangar ◽  
Lokesh Kumar Bhatt
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Neurological Disorders ◽  
Therapeutic Targets ◽  
Therapeutic Failure ◽  
Hyperactivity Disorder ◽  
Novel Targets ◽  
New Therapeutic Targets ◽  
Dual Mechanism ◽  
Seizure Suppression

One of the most common neurological disorders, which occurs among 1% of the population worldwide, is epilepsy. Therapeutic failure is common with epilepsy and nearly about 30% of patients fall in this category. Seizure suppression should not be the only goal while treating epilepsy but associated comorbidities, which can further worsen the condition, should also be considered. Treatment of such comorbidities such as depression, anxiety, cognition, attention deficit hyperactivity disorder and, various other disorders which co-exist with epilepsy or are caused due to epilepsy should also be treated. Novel targets or the existing targets are needed to be explored for the dual mechanism which can suppress both the disease and the comorbidity. New therapeutic targets such as IDO, nNOS, PAR1, NF-κb are being explored for their role in epilepsy and various comorbidities. This review explores recent therapeutic targets for the treatment of comorbidities associated with epilepsy.

Nonuniform Hyper-Network Embedding with Dual Mechanism

2020 ◽  
Vol 38 (3) ◽  
pp. 1-18
Author(s):  
Jie Huang ◽  
Chuan Chen ◽  
Fanghua Ye ◽  
Weibo Hu ◽  
Zibin Zheng
Keyword(s):  
Network Embedding ◽  
Dual Mechanism

Structural Analysis and Performance in a Dual‐Mechanism Conductive Filament Memristor

2021 ◽  
pp. 2100605
Author(s):  
Shu‐Chin Tsai ◽  
Hong‐Yang Lo ◽  
Chih‐Yang Huang ◽  
Min‐Ci Wu ◽  
Yi‐Tang Tseng ◽  
...  
Keyword(s):  
Structural Analysis ◽  
Conductive Filament ◽  
And Performance ◽  
Dual Mechanism

A dual mechanism for intrinsic f0

2021 ◽  
Vol 87 ◽  
pp. 101063
Author(s):  
Wei-Rong Chen ◽  
D.H. Whalen ◽  
Mark K. Tiede
Keyword(s):  
Dual Mechanism

Evidence for a Dual Mechanism in the Anesthetic Action of an Opioid Peptide

1985 ◽  
Vol 62 (5) ◽  
pp. 615-620 ◽  
Author(s):  
Barbara A. Dodson ◽  
Keith W. Miller
Keyword(s):  
Opioid Peptide ◽  
Anesthetic Action ◽  
Dual Mechanism
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