Antibacterial Discovery via Phenotypic DNA-Encoded Library Screening

2021 ◽  
Author(s):  
Wesley G. Cochrane ◽  
Patrick R. Fitzgerald ◽  
Brian M. Paegel
Keyword(s):  
Library Screening

scholarly journals A “No‐Touch” Antibody‐Staining Method of Adherent Cells for High‐Throughput Flow Cytometry in 384‐Well Microplate Format for Cell‐Based Drug Library Screening

2019 ◽  
Vol 97 (8) ◽  
pp. 845-851 ◽  
Author(s):  
Annelisa M. Cornel ◽  
Celina L. Szanto ◽  
Niek P. Til ◽  
Jeroen F. Velzen ◽  
Jaap J. Boelens ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
High Throughput ◽  
Staining Method ◽  
Adherent Cells ◽  
Library Screening ◽  
Antibody Staining

scholarly journals CRISPR/Cas9 high-throughput screening in cancer research

2020 ◽  
Vol 185 ◽  
pp. 03032
Author(s):  
Zhuoxin Liu
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Genomic Library ◽  
Gene Activation ◽  
Library Screening ◽  
Basic Principles ◽  
Tumor Research ◽  
Technology Strategies ◽  
Target Effect ◽  
Main Strategy

In recent years, CRISPR/Cas9 technology has developed rapidly. With its accurate, fast, and simple editing functions that can achieve gene activation, interference, knockout, and knock-in, it has become a powerful genetic screening tool that is widely used in various models, including cell lines of mice and zebrafish. The use of CRISPR system to construct a genomic library for high-throughput screening is the main strategy for research of disease, especially tumor target gene research. This article reviews the basic principles and latest developments of CRISPR/Cas9 library screening technology strategies to improve its off-target effect, the basic workflow of library screening, and its application in tumor research.

Identification of herbicide resistance OsACC1 mutations via in planta prime-editing-library screening in rice

Nature Plants ◽  
2021 ◽  
Author(s):  
Rongfang Xu ◽  
Xiaoshuang Liu ◽  
Juan Li ◽  
Ruiying Qin ◽  
Pengcheng Wei
Keyword(s):  
Herbicide Resistance ◽  
Library Screening ◽  
In Planta

scholarly journals Identification of Human Kinases Involved in Hepatitis C Virus Replication by Small Interference RNA Library Screening

2007 ◽  
Vol 283 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Lubica Supekova ◽  
Frantisek Supek ◽  
Jongkook Lee ◽  
Shawn Chen ◽  
Nathanael Gray ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Replication ◽  
Library Screening ◽  
Small Interference Rna ◽  
Interference Rna

Identification of baicalein as a ferroptosis inhibitor by natural product library screening

2016 ◽  
Vol 473 (4) ◽  
pp. 775-780 ◽  
Author(s):  
Yangchun Xie ◽  
Xinxin Song ◽  
Xiaofang Sun ◽  
Jin Huang ◽  
Meizuo Zhong ◽  
...  
Keyword(s):  
Natural Product ◽  
Library Screening ◽  
Natural Product Library
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