N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes

2021 ◽  
Author(s):  
Melanie A. Higgins ◽  
Gregor Tegl ◽  
Spencer S. MacDonald ◽  
Gregory Arnal ◽  
Harry Brumer ◽  
...  
Keyword(s):  
Common Core ◽  
Degradation Pathways ◽  
Glycan Degradation ◽  
Core Genes

scholarly journals Functional Identification of the Proteusmirabilis Core Lipopolysaccharide Biosynthesis Genes

2010 ◽  
Vol 192 (17) ◽  
pp. 4413-4424 ◽  
Author(s):  
Eleonora Aquilini ◽  
Joana Azevedo ◽  
Natalia Jimenez ◽  
Lamiaa Bouamama ◽  
Juan M. Tomás ◽  
...  
Keyword(s):  
Gene Cluster ◽  
Common Core ◽  
Outer Core ◽  
Genetic Complementation ◽  
Biosynthetic Gene ◽  
Functional Identification ◽  
The Core ◽  
Lipopolysaccharide Biosynthesis ◽  
The Common ◽  
Core Genes

ABSTRACT In this study, we report the identification of genes required for the biosynthesis of the core lipopolysaccharides (LPSs) of two strains of Proteus mirabilis. Since P. mirabilis and Klebsiella pneumoniae share a core LPS carbohydrate backbone extending up to the second outer-core residue, the functions of the common P. mirabilis genes was elucidated by genetic complementation studies using well-defined mutants of K. pneumoniae. The functions of strain-specific outer-core genes were identified by using as surrogate acceptors LPSs from two well-defined K. pneumoniae core LPS mutants. This approach allowed the identification of two new heptosyltransferases (WamA and WamC), a galactosyltransferase (WamB), and an N-acetylglucosaminyltransferase (WamD). In both strains, most of these genes were found in the so-called waa gene cluster, although one common core biosynthetic gene (wabO) was found outside this cluster.

Standardization of common core tests.

1957 ◽  
Author(s):  
James B. Trump ◽  
Richard K. White ◽  
Cecil D. Johnson ◽  
Edmund F. Fuchs
Keyword(s):  
Common Core
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