Decarboxylation of Aromatic Carboxylic Acids by the Prenylated-FMN-dependent Enzyme Phenazine-1-carboxylic Acid Decarboxylase

ACS Catalysis ◽  
2021 ◽  
pp. 11723-11732
Author(s):  
Prathamesh M. Datar ◽  
E. Neil G. Marsh
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Acid Decarboxylase ◽  
Aromatic Carboxylic Acids

scholarly journals Efficient one-pot, four-component synthesis of N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,4-oxadiazol-2-yl]cyclobutyl}amine derivatives from the reaction of (isocyanoimino)triphenylphosphorane, dibenzylamine, an aromatic carboxylic acid and cyclobutanone

2012 ◽  
Vol 77 (9) ◽  
pp. 1175-1180 ◽  
Author(s):  
Nahid Shajari ◽  
Reza Kazemizadeh ◽  
Ali Ramazani
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Room Temperature ◽  
Aromatic Carboxylic Acid ◽  
One Pot ◽  
Aromatic Carboxylic Acids ◽  
High Yields ◽  
Neutral Conditions

Four-component reaction of cyclobutanone, dibenzylamine and (Nisocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford N,N-dibenzyl-N-{1-[5-(3-aryl)-1,3,4-oxadiazol-2-yl]cyclobutyl}amine derivatives in high yields.

Rh(III)-Catalyzed Decarboxylativeortho-Heteroarylation of Aromatic Carboxylic Acids by Using the Carboxylic Acid as a Traceless Directing Group

2015 ◽  
Vol 17 (7) ◽  
pp. 1762-1765 ◽  
Author(s):  
Xurong Qin ◽  
Denan Sun ◽  
Qiulin You ◽  
Yangyang Cheng ◽  
Jingbo Lan ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Aromatic Carboxylic Acids ◽  
Directing Group

Organocatalytic Electrochemical C–H Lactonization of Aromatic Carboxylic Acids

Synthesis ◽  
2018 ◽  
Vol 50 (15) ◽  
pp. 2924-2929 ◽  
Author(s):  
Sanzhong Luo ◽  
Longji Li ◽  
Qi Yang ◽  
Zongbin Jia
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Glassy Carbon ◽  
Bond Formation ◽  
Carbon Electrodes ◽  
Glassy Carbon Electrodes ◽  
Aromatic Carboxylic Acids ◽  
Radical Substitution ◽  
Carboxyl Radical ◽  
Oxygen Bond

An electrochemical strategy has been developed for radical arene carbon–oxygen bond formation. This reaction utilizes DDQ as a redox mediator, with inexpensive glassy carbon electrodes to facilitate an intramolecular lactonization of biphenyl-2-carboxylic acid derivatives via aromatic carboxyl radical substitution to give 6H-benzo[c]chromen-6-ones.

Chemoselectivity in Esterification Reactions – Size Matters after All

Synthesis ◽  
2017 ◽  
Vol 49 (15) ◽  
pp. 3460-3470 ◽  
Author(s):  
Julian Helberg ◽  
Marta Marin-Luna ◽  
Hendrik Zipse
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Temperature Effects ◽  
Aliphatic Acid ◽  
Secondary Alcohols ◽  
Acid Chlorides ◽  
Aromatic Carboxylic Acids ◽  
Esterification Reactions

The reaction of carboxylic acid chlorides with secondary alcohols carrying either flexible alkyl or rigid aryl substituents was studied through a series of competition experiments. Aliphatic acid chlorides react preferentially with the aryl-substituted alcohols, while acid chlorides derived from aromatic carboxylic acids react with very low selectivity. Catalysis by 9-azajulolidine (TCAP) increases the selectivity strongly, while solvent and temperature effects are only moderate. The size of the alcohol substituents seems to impact selectivities only for rigid aryl substituents, and highest selectivities have been found for 1-(1-pyrenyl)ethanol.

Study on solubilization of telmisartan by forming cocrystal with aromatic carboxylic acid

CrystEngComm ◽  
2021 ◽  
Author(s):  
Guojia Yu ◽  
Xinjian Chen ◽  
Lichao He ◽  
Xiangrong Li ◽  
Zhiyong Zhou ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Aromatic Carboxylic Acid ◽  
Aromatic Carboxylic Acids

The solubility of insoluble telmisartan (TEL) was improved by forming new cocrystal forms with several aromatic carboxylic acids. All solid forms showed three dissolution modes: TEL-HBA achieved maximum release equilibrium...

Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde

2018 ◽  
Vol 21 (4) ◽  
pp. 298-301 ◽  
Author(s):  
Ghasem Marandi
Keyword(s):  
Biological Sciences ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
High Performance ◽  
Condensation Reaction ◽  
Aromatic Aldehydes ◽  
New Materials ◽  
One Pot ◽  
High Yields ◽  
Benzaldehyde Derivatives

Aim and Objective: The reaction of cyclohexylisocyanide and 2-aminopyridine-3- carboxylic acid in the presence of benzaldehyde derivatives in ethanol led to 3-(cyclohexylamino)-2- arylimidazo[1,2-a]pyridine-8-carboxylic acids in high yields. In a three component condensation reaction, isocyanide reacts with 2-aminopyridine-3-carboxylic acid and aromatic aldehydes without any prior activation. Material and Methods: The synthesized products have stable structures which have been characterized by IR, 1H, 13C and Mass spectroscopy as well as CHN-O analysis. Results: In continuation of our attempts to develop simple one-pot routes for the synthesis of 3- (cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids, aromatic aldehydes with divers substituted show a high performance. Conclusion: In conclusion, this study introduces the art of combinatorial chemistry using a simple one-pot procedure for the synthesis of new materials which are interesting compounds in medicinal and biological sciences.

scholarly journals Propylphosphonic acid anhydride–mediated amidation of Morita–Baylis–Hillman–derived indolizine-2-carboxylic acids

2021 ◽  
pp. 174751982098715
Author(s):  
Khethobole C Sekgota ◽  
Michelle Isaacs ◽  
Heinrich C Hoppe ◽  
Ronnett Seldon ◽  
Digby F Warner ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Coupling Agent ◽  
Methyl Esters ◽  
Acid Anhydride

Propylphosphonic acid anhydride has been successfully used as a coupling agent in the synthesis of a series of indolizine-2-carboxamido derivatives from indolizine-2-carboxylic acid and its 3-acetylated analogue. The acid substrates were obtained by saponification of the corresponding methyl esters produced, in turn, selectively and efficiently, by time-controlled cyclisation of a single Morita–Baylis–Hillman adduct. Various amino and hydrazino compounds with medicinal potential have been used to prepare indolizine-2-carboxamido and hydrazido derivatives.

Intercalated Organo-Bentonite as Efficient Biosorbent for Aromatic Carboxylic Acids from Wastewater

2021 ◽  
pp. 116443
Author(s):  
N. Bensid ◽  
R. Zerdoum ◽  
Z. Hattab ◽  
Y. Boutaleb ◽  
M. Bououdina
Keyword(s):  
Carboxylic Acids ◽  
Aromatic Carboxylic Acids
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