scholarly journals Asymmetric Allylic Alkylation of β-Ketoesters via C–N Bond Cleavage of N-Allyl-N-methylaniline Derivatives Catalyzed by a Nickel–Diphosphine System

ACS Catalysis ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 5828-5839
Author(s):  
Haruki Nagae ◽  
Jingzhao Xia ◽  
Evgueni Kirillov ◽  
Kosuke Higashida ◽  
Koya Shoji ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation

Kinetic resolution of primary allylic amines via palladium-catalyzed asymmetric allylic alkylation of malononitriles

2015 ◽  
Vol 13 (19) ◽  
pp. 5367-5371 ◽  
Author(s):  
Yong Wang ◽  
Ya-Nan Xu ◽  
Guo-Sheng Fang ◽  
Hong-Jian Kang ◽  
Yonghong Gu ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Bond Cleavage ◽  
Allylic Alkylation ◽  
Allylic Amines ◽  
Asymmetric Allylic Alkylation ◽  
New Strategy ◽  
Palladium Catalyzed

A new strategy has been developed for the catalytic kinetic resolution of primary allylic amines via enantioselective C–N bond cleavage.

Novel Chiral Ligands for Palladium-catalyzed Asymmetric Allylic Alkylation/ Asymmetric Tsuji-Trost Reaction: A Review

2019 ◽  
Vol 23 (11) ◽  
pp. 1168-1213 ◽  
Author(s):  
Samar Noreen ◽  
Ameer Fawad Zahoor ◽  
Sajjad Ahmad ◽  
Irum Shahzadi ◽  
Ali Irfan ◽  
...  
Keyword(s):  
Asymmetric Catalysis ◽  
Enantioselective Synthesis ◽  
Chiral Ligands ◽  
Allylic Alkylation ◽  
Research Groups ◽  
Asymmetric Allylic Alkylation ◽  
Catalytic Potential ◽  
Long Time ◽  
Palladium Catalyzed ◽  
Alkylation Reactions

Background: Asymmetric catalysis holds a prestigious role in organic syntheses since a long time and chiral inductors such as ligands have been used to achieve the utmost desired results at this pitch. The asymmetric version of Tsuji-Trost allylation has played a crucial role in enantioselective synthesis. Various chiral ligands have been known for Pdcatalyzed Asymmetric Allylic Alkylation (AAA) reactions and exhibited excellent catalytic potential. The use of chiral ligands as asymmetric inductors has widened the scope of Tsuji-Trost allylic alkylation reactions. Conclusion: Therefore, in this review article, a variety of chiral inductors or ligands have been focused for palladium catalyzed asymmetric allylic alkylation (Tsuji-Trost allylation) and in this regard, recently reported literature (2013-2017) has been described. The use of ligands causes the induction of enantiodiscrimination to the allylated products, therefore, the syntheses of various kinds of ligands have been targeted by many research groups to employ in Pd-catalyzed AAA reactions.

Cytisine as a scaffold for ortho-diphenylphosphinobenzenecarboxamide ligands for Pd-catalyzed asymmetric allylic alkylation

2015 ◽  
Vol 778 ◽  
pp. 10-20 ◽  
Author(s):  
Irena Philipova ◽  
Georgi Stavrakov ◽  
Nikolay Vassilev ◽  
Rositsa Nikolova ◽  
Boris Shivachev ◽  
...  
Keyword(s):  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation
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