Scalable Aqueous Reversible Addition–Fragmentation Chain Transfer Photopolymerization-Induced Self-Assembly of Acrylamides for Direct Synthesis of Polymer Nanoparticles for Potential Drug Delivery Applications

2019 ◽  
Vol 1 (6) ◽  
pp. 1251-1256 ◽  
Author(s):  
Neomy Zaquen ◽  
Huijie Zu ◽  
Ak M.N.B.P.H.A. Kadir ◽  
Tanja Junkers ◽  
Per B. Zetterlund ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Chain Transfer ◽  
Direct Synthesis ◽  
Polymer Nanoparticles ◽  
Potential Drug ◽  
Reversible Addition ◽  
Drug Delivery Applications

Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene ◽  
First Time

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

scholarly journals Synthesis of aminated polystyrene and its self-assembly with nanoparticles at oil/water interface

e-Polymers ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 317-327
Author(s):  
Chenliang Shi ◽  
Ling Lin ◽  
Yukun Yang ◽  
Wenjia Luo ◽  
Maoqing Deng ◽  
...  
Keyword(s):  
Interfacial Tension ◽  
Self Assembly ◽  
Carbon Dots ◽  
Chain Transfer ◽  
Functionalized Polymers ◽  
Amino Groups ◽  
One Dimensional ◽  
Reversible Addition ◽  
Oil Water ◽  
Chain Transfer Polymerization

AbstractThe influence of density of amino groups, nanoparticles dimension and pH on the interaction between end-functionalized polymers and nanoparticles was extensively investigated in this study. PS–NH2 and H2N–PS–NH2 were prepared using reversible addition–fragmentation chain transfer polymerization and atom transfer radical polymerization. Zero-dimensional carbon dots with sulfonate groups, one-dimensional cellulose nanocrystals with sulfate groups and two-dimensional graphene with sulfonate groups in the aqueous phase were added into the toluene phase containing the aminated PS. The results indicate that aminated PS exhibited the strongest interfacial activity after compounding with sulfonated nanoparticles at a pH of 3. PS ended with two amino groups performed better in reducing the water/toluene interfacial tension than PS ended with only one amino group. The dimension of sulfonated nanoparticles also contributed significantly to the reduction in the water/toluene interfacial tension. The minimal interfacial tension was 4.49 mN/m after compounding PS–NH2 with sulfonated zero-dimensional carbon dots.

Synthesis and Characterization of pH-Sensitive Biodegradable Polyurethane for Potential Drug Delivery Applications

2011 ◽  
Vol 44 (4) ◽  
pp. 857-864 ◽  
Author(s):  
Lijuan Zhou ◽  
Lunquan Yu ◽  
Mingming Ding ◽  
Jiehua Li ◽  
Hong Tan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ph Sensitive ◽  
Synthesis And Characterization ◽  
Potential Drug ◽  
Biodegradable Polyurethane ◽  
Drug Delivery Applications

scholarly journals Self-assembly of the monohydroxy triterpenoid lupeol yielding nano-fibers, sheets and gel: environmental and drug delivery applications

RSC Advances ◽  
2021 ◽  
Vol 11 (53) ◽  
pp. 33500-33510
Author(s):  
Saikat Kumar Panja ◽  
Soumen Patra ◽  
Braja Gopal Bag
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Organic Liquids ◽  
Supramolecular Gels ◽  
Drug Delivery Applications

The monohydroxy triterpenoid lupeol forms gels in organic and aqueous organic liquids via self-assembly. The resulting supramolecular gels could be utilized for pollutant capture, drug entrapment and release applications.

Design of interpenetrating chitosan and poly(ethylene glycol) sponges for potential drug delivery applications

2017 ◽  
Vol 170 ◽  
pp. 166-175 ◽  
Author(s):  
Lisa Racine ◽  
Guillaume Costa ◽  
Eric Bayma-Pecit ◽  
Isabelle Texier ◽  
Rachel Auzély-Velty
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene

The photo-controlled polymerization-induced self-assembly and reorganization process for fabrication of polymeric nanomaterials

2017 ◽  
Vol 1 (6) ◽  
pp. 1200-1206 ◽  
Author(s):  
Jiemei Zhou ◽  
Chunyan Hong ◽  
Caiyuan Pan
Keyword(s):  
Visible Light ◽  
Self Assembly ◽  
Dispersion Polymerization ◽  
Chain Transfer ◽  
Chain Transfer Agent ◽  
Controlled Polymerization ◽  
Dimethylaminoethyl Methacrylate ◽  
Reversible Addition

A visible light mediated reversible addition–fragmentation chain transfer (RAFT) dispersion polymerization of benzyl methacrylate (BzMA) is conducted in ethanol using poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) as a macro-chain transfer agent (macro-CTA), affording polymeric nanomaterials with various morphologies.

scholarly journals Synthesis of non-ionic bolaamphiphiles and study of their self-assembly and transport behaviour for drug delivery applications

RSC Advances ◽  
2018 ◽  
Vol 8 (55) ◽  
pp. 31777-31782 ◽  
Author(s):  
Rashmi Rashmi ◽  
Abhishek K. Singh ◽  
Katharina Achazi ◽  
Boris Schade ◽  
Christoph Böttcher ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Transport Behaviour ◽  
Drug Delivery Applications

Non-ionic bolaamphiphiles as nanocarrier for biomedical applications.

Carrageenan: A Wonder Polymer from Marine Algae for Potential Drug Delivery Applications

2019 ◽  
Vol 25 (11) ◽  
pp. 1172-1186 ◽  
Author(s):  
Dilshad Qureshi ◽  
Suraj Kumar Nayak ◽  
Samarendra Maji ◽  
Doman Kim ◽  
Indranil Banerjee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biological Activities ◽  
Medical Science ◽  
Drug Carriers ◽  
Sulfated Polysaccharides ◽  
Potential Drug ◽  
Natural Polymers ◽  
Structural Variations ◽  
Varied Range ◽  
Drug Delivery Applications

Background: With the advancement in the field of medical science, the idea of sustained release of the therapeutic agents in the patient’s body has remained a major thrust for developing advanced drug delivery systems (DDSs). The critical requirement for fabricating these DDSs is to facilitate the delivery of their cargos in a spatio-temporal and pharmacokinetically-controlled manner. Albeit the synthetic polymer-based DDSs normally address the above-mentioned conditions, their potential cytotoxicity and high cost have ultimately constrained their success. Consequently, the utilization of natural polymers for the fabrication of tunable DDSs owing to their biocompatible, biodegradable, and non-toxic nature can be regarded as a significant stride in the field of drug delivery. Marine environment serves as an untapped resource of varied range of materials such as polysaccharides, which can easily be utilized for developing various DDSs. Methods: Carrageenans are the sulfated polysaccharides that are extracted from the cell wall of red seaweeds. They exhibit an assimilation of various biological activities such as anti-thrombotic, anti-viral, anticancer, and immunomodulatory properties. The main aim of the presented review is threefold. The first one is to describe the unique physicochemical properties and structural composition of different types of carrageenans. The second is to illustrate the preparation methods of the different carrageenan-based macro- and micro-dimensional DDSs like hydrogels, microparticles, and microspheres respectively. Fabrication techniques of some advanced DDSs such as floating hydrogels, aerogels, and 3-D printed hydrogels have also been discussed in this review. Next, considerable attention has been paid to list down the recent applications of carrageenan-based polymeric architectures in the field of drug delivery. Results: Presence of structural variations among the different carrageenan types helps in regulating their temperature and ion-dependent sol-to-gel transition behavior. The constraint of low mechanical strength of reversible gels can be easily eradicated using chemical crosslinking techniques. Carrageenan based-microdimesional DDSs (e.g. microspheres, microparticles) can be utilized for easy and controlled drug administration. Moreover, carrageenans can be fabricated as 3-D printed hydrogels, floating hydrogels, and aerogels for controlled drug delivery applications. Conclusion: In order to address the problems associated with many of the available DDSs, carrageenans are establishing their worth recently as potential drug carriers owing to their varied range of properties. Different architectures of carrageenans are currently being explored as advanced DDSs. In the near future, translation of carrageenan-based advanced DDSs in the clinical applications seems inevitable.

Small-Molecule Probe for Sensing Serum Albumin with Consequential Self-Assembly as a Fluorescent Organic Nanoparticle for Bioimaging and Drug-Delivery Applications

2020 ◽  
Vol 3 (5) ◽  
pp. 3099-3113 ◽  
Author(s):  
Subhajit Guria ◽  
Avijit Ghosh ◽  
Priyanka Upadhyay ◽  
Manas kumar Das ◽  
Tanushree Mishra ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Serum Albumin ◽  
Small Molecule ◽  
Self Assembly ◽  
Drug Delivery Applications ◽  
Small Molecule Probe
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