scholarly journals Hydrophilic and Double Hydrophilic/Hydrophobic Microcapsules using a Single, Thermally Responsive, Self-Sorting Dispersant

2021 ◽  
Author(s):  
Lérys Granado ◽  
Céline Burel ◽  
Rémi Giordanengo ◽  
Ahmed Alsayed ◽  
Denis Bendejacq ◽  
...  
Keyword(s):  
Thermally Responsive

New star-shape memory polyurethanes capable of thermally induced recovery and hydrogen bond-self-healing

2021 ◽  
Author(s):  
Zonghui Huang ◽  
Jianfeng Ban ◽  
Lulu Pan ◽  
Shuqing Cai ◽  
Junqiu Liao
Keyword(s):  
Hydrogen Bond ◽  
Shape Memory ◽  
Self Healing ◽  
Thermally Induced ◽  
Thermally Responsive

Star-shape memory polyurethanes that combine thermally responsive and self-healing properties.

scholarly journals Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Liping Huang ◽  
Yiyi Zhang ◽  
Yanan Li ◽  
Fanling Meng ◽  
Hongyu Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Near Infrared ◽  
Immune Escape ◽  
Regulatory Protein ◽  
In Vivo Studies ◽  
Breast Cancer Patients ◽  
Thermally Responsive ◽  
Immunosuppressive Microenvironment

AbstractThe highly immunosuppressive microenvironment after surgery has a crucial impact on the recurrence and metastasis in breast cancer patients. Programmable delivery of immunotherapy-involving combinations through a single drug delivery system is highly promising, yet greatly challenging, to reverse postoperative immunosuppression. Here, an injectable hierarchical gel matrix, composed of dual lipid gel (DLG) layers with different soybean phosphatidylcholine/glycerol dioleate mass ratios, was developed to achieve the time-programmed sequential delivery of combined cancer immunotherapy. The outer layer of the DLG matrix was thermally responsive and loaded with sorafenib-adsorbed graphene oxide (GO) nanoparticles. GO under manually controlled near-infrared irradiation generated mild heat and provoked the release of sorafenib first to reeducate tumor-associated macrophages (TAMs) and promote an immunogenic tumor microenvironment. The inner layer, loaded with anti-CD47 antibody (aCD47), could maintain the gel state for a much longer time, enabling the sustained release of aCD47 afterward to block the CD47-signal regulatory protein α (SIRPα) pathway for a long-term antitumor effect. In vivo studies on 4T1 tumor-bearing mouse model demonstrated that the DLG-based strategy efficiently prevented tumor recurrence and metastasis by locally reversing the immunosuppression and synergistically blocking the CD47-dependent immune escape, thereby boosting the systemic immune responses.

Thermally Responsive Biomineralization on Biodegradable Substrates

2007 ◽  
Vol 17 (16) ◽  
pp. 3312-3318 ◽  
Author(s):  
J. Shi ◽  
N. M. Alves ◽  
J. F. Mano
Keyword(s):  
Thermally Responsive

Thermally responsive rigid polymer monoliths

1997 ◽  
Vol 9 (8) ◽  
pp. 630-633 ◽  
Author(s):  
Eric C. Peters ◽  
Frantisek Svec ◽  
Jean M. J. Fréchet
Keyword(s):  
Polymer Monoliths ◽  
Rigid Polymer ◽  
Thermally Responsive

Design of Thermally Responsive Polymeric Hydrogels for Brackish Water Desalination: Effect of Architecture on Swelling, Deswelling, and Salt Rejection

2015 ◽  
Vol 7 (29) ◽  
pp. 15696-15706 ◽  
Author(s):  
Wael Ali ◽  
Beate Gebert ◽  
Tobias Hennecke ◽  
Karlheinz Graf ◽  
Mathias Ulbricht ◽  
...  
Keyword(s):  
Brackish Water ◽  
Water Desalination ◽  
Salt Rejection ◽  
Thermally Responsive ◽  
Polymeric Hydrogels

Wetting behaviour and direct observation of thermally responsive polystyrene-block -poly(N -isopropylacrylamide)-block -polystyrene electrospun fibres in aqueous environment

2013 ◽  
Vol 63 (1) ◽  
pp. 37-43 ◽  
Author(s):  
Antti Nykänen ◽  
Sami-Pekka Hirvonen ◽  
Heikki Tenhu ◽  
Raffaele Mezzenga ◽  
Janne Ruokolainen
Keyword(s):  
Direct Observation ◽  
Aqueous Environment ◽  
Thermally Responsive

New Cyclic Olefin Copolymer for the Preparation of Thermally Responsive Luminescent Films

2009 ◽  
Vol 210 (9) ◽  
pp. 728-735 ◽  
Author(s):  
Filippo Donati ◽  
Andrea Pucci ◽  
Laura Boggioni ◽  
Incoronata Tritto ◽  
Giacomo Ruggeri
Keyword(s):  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin ◽  
Thermally Responsive ◽  
Luminescent Films

scholarly journals Is behavioural plasticity consistent across different environmental gradients and through time?

2017 ◽  
Vol 284 (1860) ◽  
pp. 20170893 ◽  
Author(s):  
David J. Mitchell ◽  
Peter A. Biro
Keyword(s):  
Food Deprivation ◽  
Environmental Gradients ◽  
Reaction Norm ◽  
Environmental Variable ◽  
Behavioural Plasticity ◽  
Thermally Responsive ◽  
State Dependent ◽  
Energetic Constraints ◽  
High Consistency ◽  
Outstanding Question

Despite accumulating evidence for individual variation in behavioural plasticity, there is currently little understanding of the causes and consequences of this variation. An outstanding question is whether individual reaction norm (RN) slopes are consistent across different environmental variables—that is, whether an individual that is highly responsive to one environmental variable will be equally responsive to a second variable. Another important and related question is whether RNs are themselves consistently expressed through time or whether they are simply state dependent. Here, we quantified individual activity rates of zebrafish in response to independent manipulations of temperature and food availability that were repeated in discrete ‘bursts’ of sampling through time. Individuals that were thermally responsive were not more responsive to food deprivation, but they did exhibit greater unexplained variation. Individual RN slopes were consistent (repeatable) over time for both temperature (Rslope= 0.92) and food deprivation responses (Rslope= 0.4), as were mean activity rates in the standard environment (Rintercept= 0.83). Despite the high potential lability of behaviour, we have demonstrated consistency of behavioural RN components and identified potential energetic constraints leading to high consistency of thermal RNs and low consistency of food deprivation RNs.

Sign in / Sign up

Export Citation Format

Share Document