scholarly journals MnO Nanoparticles Embedded in Functional Polymers as T1 Contrast Agents for Magnetic Resonance Imaging

2020 ◽  
Vol 3 (4) ◽  
pp. 3787-3797 ◽  
Author(s):  
Michele Mauri ◽  
Veronica Collico ◽  
Lucia Morelli ◽  
Pradip Das ◽  
Isabel García ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Functional Polymers ◽  
Resonance Imaging ◽  
T1 Contrast

scholarly journals Iron Oxide Nanoparticles: An Alternative for Positive Contrast in Magnetic Resonance Imaging

Inorganics ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 28 ◽  
Author(s):  
Irene Fernández-Barahona ◽  
María Muñoz-Hernando ◽  
Jesus Ruiz-Cabello ◽  
Fernando Herranz ◽  
Juan Pellico
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Positive Contrast ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
The Past ◽  
T1 Contrast

Iron oxide nanoparticles have been extensively utilised as negative (T2) contrast agents in magnetic resonance imaging. In the past few years, researchers have also exploited their application as positive (T1) contrast agents to overcome the limitation of traditional Gd3+ contrast agents. To provide T1 contrast, these particles must present certain physicochemical properties with control over the size, morphology and surface of the particles. In this review, we summarise the reported T1 iron oxide nanoparticles and critically revise their properties, synthetic protocols and application, not only in MRI but also in multimodal imaging. In addition, we briefly summarise the most important nanoparticulate Gd and Mn agents to evaluate whether T1 iron oxide nanoparticles can reach Gd/Mn contrast capabilities.

MnII-containing coordination nanoparticles as highly efficient T1 contrast agents for magnetic resonance imaging

2014 ◽  
Vol 50 (51) ◽  
pp. 6740-6743 ◽  
Author(s):  
Gabriella Paul ◽  
Yoann Prado ◽  
Nada Dia ◽  
Eric Rivière ◽  
Sophie Laurent ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Prussian Blue ◽  
Resonance Imaging ◽  
Prussian Blue Analogues ◽  
Highly Efficient ◽  
T1 Contrast

Nanoparticles of MnII-containing Prussian blue analogues reveal large longitudinal relaxivities exceeding that of clinical contrast agents.

Preparation of linear poly(glycerol) as a T1 contrast agent for tumor-targeted magnetic resonance imaging

2016 ◽  
Vol 4 (41) ◽  
pp. 6716-6725 ◽  
Author(s):  
Yi Cao ◽  
Min Liu ◽  
Kunchi Zhang ◽  
Jingjin Dong ◽  
Guangyue Zu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Small Molecule ◽  
Resonance Imaging ◽  
T1 Contrast Agent ◽  
T1 Contrast ◽  
Linear Poly

Macromolecular contrast agents (CAs) labeled with targeting molecules are gaining remarkable interest as promising materials overcoming the defects of small-molecule CAs.

Supramolecular Enhancement of Aminoxyl ORCA Contrast Agents

2019 ◽  
Author(s):  
Hamilton Lee ◽  
Jenica Lumata ◽  
Michael A. Luzuriaga ◽  
Candace Benjamin ◽  
Olivia Brohlin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Side Effects ◽  
Magnetic Resonance ◽  
Tobacco Mosaic Virus ◽  
Contrast Agents ◽  
Single Molecule ◽  
Organic Radical ◽  
Resonance Imaging ◽  
Physiological Conditions

<div><div><div><p>Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo. We further over came the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.</p></div></div></div>

scholarly journals Magnetic resonance thermometry using a GdIII-based contrast agent

2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Resonance Imaging ◽  
Magnetic Resonance Thermometry

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.

Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

2021 ◽  
Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Selective Cytotoxicity ◽  
Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

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