Cell Membrane-Coated Porphyrin Metal–Organic Frameworks for Cancer Cell Targeting and O2-Evolving Photodynamic Therapy

2019 ◽  
Vol 11 (43) ◽  
pp. 39594-39602 ◽  
Author(s):  
Di Zhang ◽  
Zhongju Ye ◽  
Lin Wei ◽  
Haibin Luo ◽  
Lehui Xiao
Keyword(s):  
Photodynamic Therapy ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Metal Organic Frameworks ◽  
Cell Targeting ◽  
Metal Organic ◽  
Cancer Cell Targeting

scholarly journals A siramesine-loaded metal organic framework nanoplatform for overcoming multidrug resistance with efficient cancer cell targeting

RSC Advances ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 6919-6926
Author(s):  
Jiahui Liu ◽  
Menghuan Tang ◽  
Yanghao Zhou ◽  
Yijuan Long ◽  
Yuan Cheng ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Metal Organic Framework ◽  
Cell Targeting ◽  
Metal Organic ◽  
Cancer Cell Targeting ◽  
Organic Framework

ZIF-8@Sira/FA induces the cancer cells apoptosis and then eliminates cancer cells from the inside through the lysosomal death pathway.

Cell Membrane Capsules for Encapsulation of Chemotherapeutic and Cancer Cell Targeting in Vivo

2015 ◽  
Vol 7 (33) ◽  
pp. 18628-18637 ◽  
Author(s):  
Li-Hua Peng ◽  
Yuan-Hong Zhang ◽  
Li-Jie Han ◽  
Chen-Zhen Zhang ◽  
Jia-He Wu ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Cell Targeting ◽  
Cancer Cell Targeting

Conjugates of folic acids with zinc aminophthalocyanine for cancer cell targeting and photodynamic therapy by one-photon and two-photon excitations

2014 ◽  
Vol 2 (11) ◽  
pp. 1594-1602 ◽  
Author(s):  
By Song Wang ◽  
Jing Wang ◽  
Ji-Yao Chen
Keyword(s):  
Photodynamic Therapy ◽  
Folic Acid ◽  
Cancer Cell ◽  
Cell Targeting ◽  
Two Photon ◽  
Cancer Cell Targeting ◽  
Photon Excitations

To improve the photodynamic detection and therapy of cancers (PDT), folic acid (FA) was conjugated with zinc tetraaminophthalocyanine (ZnaPc) to form ZnaPc–FA.

scholarly journals Gold nanoparticles conjugated with anti-CD133 monoclonal antibody and 5-fluorouracil chemotherapeutic agent as nanocarriers for cancer cell targeting

RSC Advances ◽  
2021 ◽  
Vol 11 (26) ◽  
pp. 16131-16141
Author(s):  
Manali Haniti Mohd-Zahid ◽  
Siti Nadiah Zulkifli ◽  
Che Azurahanim Che Abdullah ◽  
JitKang Lim ◽  
Sharida Fakurazi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Monoclonal Antibody ◽  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Chemotherapeutic Agent ◽  
Cell Targeting ◽  
Specific Targeting ◽  
Colorectal Cancer Cells ◽  
Cancer Cell Targeting

5-FU-PEGylated AuNPs-CD133 is designed to improve specific targeting of 5-FU against colorectal cancer cells which abundantly express CD133.

⿿Blind⿿ targeting in action: From phage display to breast cancer cell targeting with peptide-gold nanoconjugates

2016 ◽  
Vol 111 ◽  
pp. 155-162 ◽  
Author(s):  
Elisabetta Galbiati ◽  
Luca Gambini ◽  
Viola Civitarese ◽  
Michela Bellini ◽  
Dario Ambrosini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Phage Display ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cell Targeting ◽  
Cancer Cell Targeting

scholarly journals The nanoscaled metal-organic framework ICR-2 as a carrier of porphyrins for photodynamic therapy

2018 ◽  
Vol 9 ◽  
pp. 2960-2967 ◽  
Author(s):  
Jan Hynek ◽  
Sebastian Jurík ◽  
Martina Koncošová ◽  
Jaroslav Zelenka ◽  
Ivana Křížová ◽  
...  
Keyword(s):  
Inorganic Chemistry ◽  
Photodynamic Therapy ◽  
Photophysical Properties ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Biological Applications ◽  
Nanoparticle Surface ◽  
Metal Organic ◽  
Unsaturated Metal Sites ◽  
First Time

Nanosized porphyrin-containing metal-organic frameworks (MOFs) attract considerable attention as solid-state photosensitizers for biological applications. In this study, we have for the first time synthesised and characterised phosphinate-based MOF nanoparticles, nanoICR-2 (Inorganic Chemistry Rez). We demonstrate that nanoICR-2 can be decorated with anionic 5,10,15,20-tetrakis(4-R-phosphinatophenyl)porphyrins (R = methyl, isopropyl, phenyl) by utilizing unsaturated metal sites on the nanoparticle surface. The use of these porphyrins allows for superior loading of the nanoparticles when compared with commonly used 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin. The nanoICR-2/porphyrin composites retain part of the free porphyrins photophysical properties, while the photodynamic efficacy is strongly affected by the R substituent at the porphyrin phosphinate groups. Thus, phosphinatophenylporphyrin with phenyl substituents has the strongest photodynamic efficacy due to the most efficient cellular uptake.

Phosphatidylserine: A cancer cell targeting biomarker

2018 ◽  
Vol 52 ◽  
pp. 17-25 ◽  
Author(s):  
Bhupender Sharma ◽  
Shamsher S. Kanwar
Keyword(s):  
Cancer Cell ◽  
Cell Targeting ◽  
Cancer Cell Targeting

scholarly journals Gold-Coated Fe3O4Nanoroses with Five Unique Functions for Cancer Cell Targeting, Imaging, and Therapy

2013 ◽  
Vol 24 (12) ◽  
pp. 1772-1780 ◽  
Author(s):  
Chunmei Li ◽  
Tao Chen ◽  
Ismail Ocsoy ◽  
Guizhi Zhu ◽  
Emir Yasun ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Cell Targeting ◽  
Cancer Cell Targeting
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