scholarly journals Flower-like Mn-Doped Magnetic Nanoparticles Functionalized with αvβ3-Integrin-Ligand to Efficiently Induce Intracellular Heat after Alternating Magnetic Field Exposition, Triggering Glioma Cell Death

2019 ◽  
Vol 11 (30) ◽  
pp. 26648-26663 ◽  
Author(s):  
S. Del Sol-Fernández ◽  
Y. Portilla-Tundidor ◽  
L. Gutiérrez ◽  
O. F. Odio ◽  
E. Reguera ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Cell Death ◽  
Magnetic Nanoparticles ◽  
Glioma Cell ◽  
Alternating Magnetic Field ◽  
Αvβ3 Integrin ◽  
Integrin Ligand ◽  
Mn Doped

scholarly journals Magnetohyperthermia for treatment of gliomas: experimental and clinical studies

2010 ◽  
Vol 8 (3) ◽  
pp. 361-367 ◽  
Author(s):  
André César da Silva ◽  
Tiago Ribeiro Oliveira ◽  
Javier Bustamante Mamani ◽  
Suzana Mária Fleury Malheiros ◽  
Lorena Favaro Pavon ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Cell Death ◽  
Magnetic Nanoparticles ◽  
Treatment Options ◽  
Malignant Gliomas ◽  
Alternating Magnetic Field ◽  
High Morbidity ◽  
Tumor Cell Death ◽  
Primary Tumors ◽  
Field Equipment

ABSTRACT Gliomas comprise a group of heterogeneous primary tumors of the central nervous system that originate from glial cells. Malignant gliomas account for the majority of primary malignant CNS tumors and are associated with high morbidity and mortality. Glioblastoma is the most frequent malignant glioma, and despite recent advances in diagnosis and new treatment options, its prognosis remains dismal. New opportunities for the development of effective therapies for malignant gliomas are urgently needed. Magnetohyperthermia consists of heat generation in the region of the tumor through the application of magnetic nanoparticles subjected to an alternating magnetic field and has shown positive results in both preclinical and clinical assays. The aim of this review was to assess the relevance of hyperthermia induced by magnetic nanoparticles in treating gliomas and to describe possible variations of the technique and its implication in the effectiveness of treatment. An electronic search in the literature of articles published from January 1990 to November 2009 was performed, in databases ISI Web of Science and PubMed, and after screening according to the inclusion criteria, 11 articles were selected. Animal models showed that magnetohyperthermia was effective in promoting tumor cell death and reducing tumor mass or increasing survival of the animals. One clinical study demonstrated that magnetohyperthermia could be applied safely and with few adverse effects. Some studies suggested that mechanisms of cell death, such as apoptosis, necrosis, and antitumor immune response were triggered by magnetohyperthermia. Based on these data, it was concluded that the technique proved to be effective in most experiments, and improvement of the nanocomposites, as well as of the alternating magnetic field equipment, can contribute towards establishing magnetohyperthermia as a promising tool to treat malignant gliomas.

Phase-change material filled hollow magnetic nanoparticles for cancer therapy and dual modal bioimaging

Nanoscale ◽  
2015 ◽  
Vol 7 (19) ◽  
pp. 9004-9012 ◽  
Author(s):  
Jinghua Li ◽  
Yan Hu ◽  
Yanhua Hou ◽  
Xinkun Shen ◽  
Gaoqiang Xu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Phase Change ◽  
Phase Change Material ◽  
Alternating Magnetic Field ◽  
Change Material

An alternating magnetic field triggered nanocarrier for drug delivery is fabricated for dual modal imaging-guided thermo-chemo cancer therapy.

In vivoheating of magnetic nanoparticles in alternating magnetic field

2004 ◽  
Vol 31 (8) ◽  
pp. 2219-2221 ◽  
Author(s):  
M. Babincová ◽  
V. Altanerová ◽  
Č. Altaner ◽  
P. Čičmanec ◽  
P. Babinec
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field

scholarly journals Control the Functionality of Thermoresponsive Enzymes Immobilized onto Magnetic Nanoparticles by the Application of Alternating Magnetic Field

2014 ◽  
Vol 38 (3-1) ◽  
pp. 98-101 ◽  
Author(s):  
Satoshi Seino ◽  
Kazunari Yoshida ◽  
Toshihiro Shikakura ◽  
Kazuma Watanabe ◽  
Yuichi Koga ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field

The dynamics of magnetic nanoparticles exposed to non-heating alternating magnetic field in biochemical applications: theoretical study

2017 ◽  
Vol 19 (2) ◽  
Author(s):  
Yuri I. Golovin ◽  
Sergey L. Gribanovsky ◽  
Dmitry Y. Golovin ◽  
Alexander O. Zhigachev ◽  
Natalia L. Klyachko ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Theoretical Study ◽  
Alternating Magnetic Field

scholarly journals Magnetic nanoparticle-conjugated polymeric micelles for combined hyperthermia and chemotherapy

Nanoscale ◽  
2015 ◽  
Vol 7 (39) ◽  
pp. 16470-16480 ◽  
Author(s):  
Hyun-Chul Kim ◽  
Eunjoo Kim ◽  
Sang Won Jeong ◽  
Tae-Lin Ha ◽  
Sang-Im Park ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Synergistic Effect ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Magnetic Nanoparticle ◽  
Polymeric Micelles ◽  
Alternating Magnetic Field ◽  
Rapid Release

The cytotoxicity of magnetic nanoparticles-conjugated polymeric micelles encapsulated with an anticancer drug on cancer cells was enhanced by the synergistic effect of heat and the rapid release of the drug under an alternating magnetic field.

scholarly journals Alternating magnetic field mediated release of fluorophores from magnetic nanoparticles by hysteretic heating

2020 ◽  
Vol 571 ◽  
pp. 348-355 ◽  
Author(s):  
Jonathan S. Casey ◽  
Julien H. Arrizabalaga ◽  
Mohammad Abu-Laban ◽  
Jeffrey C. Becca ◽  
Benjamin J. Rose ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field

Heat-Inducible Gene Expression System by Applying Alternating Magnetic Field to Magnetic Nanoparticles

2013 ◽  
Vol 3 (5) ◽  
pp. 273-279 ◽  
Author(s):  
Masaki Yamaguchi ◽  
Akira Ito ◽  
Akihiko Ono ◽  
Yoshinori Kawabe ◽  
Masamichi Kamihira
Keyword(s):  
Gene Expression ◽  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Expression System ◽  
Alternating Magnetic Field ◽  
Inducible Gene Expression ◽  
Gene Expression System ◽  
Inducible Gene

Orientation-Dependent Thermogenesis of Assembled Magnetic Nanoparticles in the Presence of an Alternating Magnetic Field

ChemPhysChem ◽  
2016 ◽  
Vol 17 (21) ◽  
pp. 3377-3384 ◽  
Author(s):  
Jianfei Sun ◽  
Fengguo Fan ◽  
Peng Wang ◽  
Siyu Ma ◽  
Lina Song ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field
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