Biocompatible Two-Dimensional Titanium Nanosheets for Multimodal Imaging-Guided Cancer Theranostics

2019 ◽  
Vol 11 (25) ◽  
pp. 22129-22140 ◽  
Author(s):  
Zhongjian Xie ◽  
Shiyou Chen ◽  
Yanhong Duo ◽  
Yao Zhu ◽  
Taojian Fan ◽  
...  
2020 ◽  
Vol 20 (11) ◽  
pp. 1340-1351 ◽  
Author(s):  
Ponnurengam M. Sivakumar ◽  
Matin Islami ◽  
Ali Zarrabi ◽  
Arezoo Khosravi ◽  
Shohreh Peimanfard

Background and objective: Graphene-based nanomaterials have received increasing attention due to their unique physical-chemical properties including two-dimensional planar structure, large surface area, chemical and mechanical stability, superconductivity and good biocompatibility. On the other hand, graphene-based nanomaterials have been explored as theranostics agents, the combination of therapeutics and diagnostics. In recent years, grafting hydrophilic polymer moieties have been introduced as an efficient approach to improve the properties of graphene-based nanomaterials and obtain new nanoassemblies for cancer therapy. Methods and results: This review would illustrate biodistribution, cellular uptake and toxicity of polymergraphene nanoassemblies and summarize part of successes achieved in cancer treatment using such nanoassemblies. Conclusion: The observations showed successful targeting functionality of the polymer-GO conjugations and demonstrated a reduction of the side effects of anti-cancer drugs for normal tissues.


2019 ◽  
Vol 12 (03) ◽  
pp. 1930001 ◽  
Author(s):  
Xiaoju Men ◽  
Zhen Yuan

Photoacoustic imaging (PAI) is a hybrid imaging method based on photoacoustic (PA) effects, which is able to capture the structure, function, and molecular information of biological tissues with high resolution. To date, therapeutic techniques under the guidance of PAI have provided new strategies for accurate diagnosis and precise treatment of tumors. In particular, conjugated polymer nanoparticles have been extensively inspected for PA-based cancer theranostics largely due to their superior optical properties such as tunable spectrum and large absorption coefficient and their good biocompatibility, and abundant functional groups. This mini-review mainly focuses on the recent advances toward the development of novel conjugated polymer nanoparticles for PA-based multimodal imaging and cancer photothermal therapy.


2018 ◽  
Vol 30 (38) ◽  
pp. 1870283 ◽  
Author(s):  
Wei Tao ◽  
Xiaoyuan Ji ◽  
Xianbing Zhu ◽  
Li Li ◽  
Junqing Wang ◽  
...  

2018 ◽  
Vol 30 (36) ◽  
pp. 1870268 ◽  
Author(s):  
Xiaoyuan Ji ◽  
Na Kong ◽  
Junqing Wang ◽  
Wenliang Li ◽  
Yuling Xiao ◽  
...  

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1902
Author(s):  
Wen Zhou ◽  
Guangzhao Yang ◽  
Xiaoyue Ni ◽  
Shanchao Diao ◽  
Chen Xie ◽  
...  

Nanomaterials have been widely applied in the field of cancer imaging and therapy. However, conventional nanoparticles including micelles and liposomes may suffer the issue of dissociation in the circulation. In contrast, crosslinked nanogels the structures of which are covalently crosslinked have better physiological stability than micelles and liposomes, making them more suitable for cancer theranostics. In this review, we summarize recent advances in crosslinked nanogels for cancer imaging and therapy. The applications of nanogels in drug and gene delivery as well as development of novel cancer therapeutic methods are first introduced, followed by the introduction of applications in optical and multimodal imaging, and imaging-guided cancer therapy. The conclusion and future direction in this field are discussed at the end of this review.


2021 ◽  
Author(s):  
Hui Huang ◽  
Wei Feng ◽  
Yu Chen

Two-dimensional materials have attracted explosive interests in biomedicine, including biosensing, imaging, drug delivery, cancer theranostics, and tissue engineering, stemming from their unique morphology, physiochemical property, and biological effect.


Biomaterials ◽  
2019 ◽  
Vol 223 ◽  
pp. 119470 ◽  
Author(s):  
Feng Liu ◽  
Lin Lin ◽  
Ying Zhang ◽  
Shu Sheng ◽  
Yanbing Wang ◽  
...  

2019 ◽  
Vol 7 (3) ◽  
pp. 368-372 ◽  
Author(s):  
Menghan Shi ◽  
Jiulong Zhang ◽  
Jingchao Li ◽  
Yu Fan ◽  
Jianhong Wang ◽  
...  

Polydopamine-coated mesoporous silica nanoparticles loaded with ultrasmall Fe3O4 nanoparticles can be prepared for multimodal imaging and combination therapy of tumors.


2020 ◽  
Vol 212 ◽  
pp. 111232
Author(s):  
Xiaotong Yang ◽  
Rongxia Wu ◽  
Na Xu ◽  
Xiu'e Li ◽  
Naijun Dong ◽  
...  

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