Biomimicry Recognition of Proteins and Cells Using a Small Array of Block Copolymers Appended with Amino Acids and Fluorophores

2019 ◽  
Vol 11 (7) ◽  
pp. 6751-6758 ◽  
Author(s):  
Shunsuke Tomita ◽  
Sayaka Ishihara ◽  
Ryoji Kurita
Keyword(s):  
Amino Acids ◽  
Block Copolymers ◽  
Small Array

Block copolymers of amino acids. I. Synthesis and structure of copolymers ofL-alanine orL-phenylalanine withD,L-lysine-d7 orD,L-lysine

Biopolymers ◽  
1977 ◽  
Vol 16 (9) ◽  
pp. 2005-2028 ◽  
Author(s):  
F. Cardinaux ◽  
J. C. Howard ◽  
G. T. Taylor ◽  
H. A. Scheraga
Keyword(s):  
Amino Acids ◽  
Block Copolymers

The behavior of poly(amino acids) containing l -cysteine and their block copolymers with poly(ethylene glycol) on gold surfaces

2013 ◽  
Vol 52 (2) ◽  
pp. 248-257 ◽  
Author(s):  
Rodolphe Obeid ◽  
Tracy Armstrong ◽  
Xiaoju Peng ◽  
Karsten Busse ◽  
Jörg Kressler ◽  
...  
Keyword(s):  
Amino Acids ◽  
Block Copolymers ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Gold Surfaces ◽  
Poly Ethylene

Block copolymers of amino acids. II. Physicochemical data on copolymers containingL-alanine orL-phenylalanine

Biopolymers ◽  
1977 ◽  
Vol 16 (9) ◽  
pp. 2029-2051 ◽  
Author(s):  
J. C. Howard ◽  
F. Cardinaux ◽  
H. A. Scheraga
Keyword(s):  
Amino Acids ◽  
Block Copolymers ◽  
Physicochemical Data

Use of sequence-specific tri-block copolymers to determine the helix-forming tendencies of amino acids

Biopolymers ◽  
1998 ◽  
Vol 39 (4) ◽  
pp. 531-536 ◽  
Author(s):  
David M. Rothwarf ◽  
V. Gary Davenport ◽  
Pu-Tau Shi ◽  
Jin-Lin Peng ◽  
Harold A. Scheraga
Keyword(s):  
Amino Acids ◽  
Block Copolymers

New block copolymers of ?-amino acids

1977 ◽  
Vol 17 (8) ◽  
pp. 515-522 ◽  
Author(s):  
F. Uralil ◽  
T. Hayashi ◽  
J. M. Anderson ◽  
A. Hiltner
Keyword(s):  
Amino Acids ◽  
Block Copolymers

Homochirality as the Signature of Extra-Terrestrial Life

1997 ◽  
Vol 161 ◽  
pp. 505-510
Author(s):  
Alexandra J. MacDermott ◽  
Laurence D. Barron ◽  
Andrè Brack ◽  
Thomas Buhse ◽  
John R. Cronin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Optical Rotation ◽  
Physical Origin ◽  
Natural Choice ◽  
Rosetta Mission ◽  
Terrestrial Life ◽  
Subsurface Layers ◽  
Solar System Bodies ◽  
Origin Of Homochirality

AbstractThe most characteristic hallmark of life is its homochirality: all biomolecules are usually of one hand, e.g. on Earth life uses only L-amino acids for protein synthesis and not their D mirror images. We therefore suggest that a search for extra-terrestrial life can be approached as a Search for Extra- Terrestrial Homochirality (SETH). The natural choice for a SETH instrument is optical rotation, and we describe a novel miniaturized space polarimeter, called the SETH Cigar, which could be used to detect optical rotation as the homochiral signature of life on other planets. Moving parts are avoided by replacing the normal rotating polarizer by multiple fixed polarizers at different angles as in the eye of the bee. We believe that homochirality may be found in the subsurface layers on Mars as a relic of extinct life, and on other solar system bodies as a sign of advanced pre-biotic chemistry. We discuss the chiral GC-MS planned for the Roland lander of the Rosetta mission to a comet and conclude with theories of the physical origin of homochirality.

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