Size-Controlled Synthesis of Drug-Loaded Zeolitic Imidazolate Framework in Aqueous Solution and Size Effect on Their Cancer Theranostics in Vivo

2018 ◽  
Vol 10 (49) ◽  
pp. 42165-42174 ◽  
Author(s):  
Dongban Duan ◽  
Hui Liu ◽  
Mengxin Xu ◽  
Mengqi Chen ◽  
Yuxiang Han ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Size Effect ◽  
Controlled Synthesis ◽  
Zeolitic Imidazolate Framework ◽  
Cancer Theranostics ◽  
Size Controlled

Size-Controlled Synthesis of Sub-10 nm PtNi3Alloy Nanoparticles and their Unusual Volcano-Shaped Size Effect on ORR Electrocatalysis

Small ◽  
2016 ◽  
Vol 12 (23) ◽  
pp. 3189-3196 ◽  
Author(s):  
Lin Gan ◽  
Stefan Rudi ◽  
Chunhua Cui ◽  
Marc Heggen ◽  
Peter Strasser
Keyword(s):  
Size Effect ◽  
Controlled Synthesis ◽  
Size Controlled

scholarly journals Size-controlled synthesis of Cu2O nanoparticles: size effect on antibacterial activity and application as a photocatalyst for highly efficient H2O2 evolution

RSC Advances ◽  
2017 ◽  
Vol 7 (82) ◽  
pp. 51822-51830 ◽  
Author(s):  
Liangbin Xiong ◽  
Huaqing Yu ◽  
Changjiang Nie ◽  
Yongjun Xiao ◽  
Qingdong Zeng ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Size Effect ◽  
High Efficiency ◽  
Controlled Synthesis ◽  
Size Dependent ◽  
Highly Efficient ◽  
Cu2o Nanoparticles ◽  
Size Controlled

Size-controlled synthesis and size-dependent antibacterial activity of Cu2O nanoparticles with high efficiency for H2O2 evolution.

Size-controlled synthesis, characterization and electrocatalytic behaviors of polymer-protected nickel nanoparticles: a comparison with respect to two polymers

RSC Advances ◽  
2014 ◽  
Vol 4 (27) ◽  
pp. 13892-13900 ◽  
Author(s):  
Partha Sarathi Roy ◽  
Swapan Kumar Bhattacharya
Keyword(s):  
Aqueous Solution ◽  
Sodium Borohydride ◽  
Polyacrylic Acid ◽  
Nickel Nanoparticles ◽  
Nickel Chloride ◽  
Polyvinyl Pyrrolidone ◽  
Controlled Synthesis ◽  
Electrochemically Active ◽  
Size Controlled

A facile reduction of nickel chloride in aqueous solution with sodium borohydride leads to fairly monodisperse, and electrochemically active nickel nanoparticles by the separate use of a capping polymer like polyvinyl pyrrolidone (PVP) and polyacrylic acid (PAA).

scholarly journals Size-controlled Synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) Crystals in an Aqueous System at Room Temperature

2012 ◽  
Vol 41 (10) ◽  
pp. 1337-1339 ◽  
Author(s):  
Shunsuke Tanaka ◽  
Koji Kida ◽  
Muneyuki Okita ◽  
Yosuke Ito ◽  
Yoshikazu Miyake
Keyword(s):  
Room Temperature ◽  
Aqueous System ◽  
Controlled Synthesis ◽  
Zeolitic Imidazolate Framework ◽  
Size Controlled

scholarly journals Size-controlled Synthesis of Zeolitic Imidazolate Framework-67 (ZIF-67) Using Electrospray in Liquid Phase

2020 ◽  
Vol 49 (8) ◽  
pp. 875-878
Author(s):  
Hiroki Konno ◽  
Miho Omata ◽  
Kouhei Kikuchi ◽  
Mana Gotou ◽  
Kousuke Yasuda ◽  
...  
Keyword(s):  
Liquid Phase ◽  
Controlled Synthesis ◽  
Zeolitic Imidazolate Framework ◽  
Size Controlled

Enhanced Stability and Controlled Delivery of MOF Encapsulated Vaccines and Their Immunogenic Response In Vivo

2018 ◽  
Author(s):  
Michael Luzuriaga ◽  
Raymond P. Welch ◽  
Madushani Dharmawardana ◽  
Candace Benjamin ◽  
Shaobo Li ◽  
...  
Keyword(s):  
Viral Vector ◽  
Controlled Delivery ◽  
Conformational Structure ◽  
Spectroscopy Analysis ◽  
Zeolitic Imidazolate Framework ◽  
Structural Conformation ◽  
Depth Study ◽  
Viral Nanoparticle

<div><div><div><p>Vaccines have an innate tendency to lose their structural conformation upon environmental and chemical stressors. A loss in conformation reduces the therapeutic ability to prevent the spread of a pathogen. Herein, we report an in-depth study of zeolitic imidazolate framework-8 (ZIF-8) and its ability to provide protection for a model viral vector against dena- turing conditions. The immunoassay and spectroscopy analysis together demonstrate enhanced thermal and chemical stability to the conformational structure of the encapsulated viral nanoparticle. The long-term biological activity of this virus-ZIF composite was investigated in animal models to further elucidate the integrity of the encapsulated virus, the bio-safety, and immunogenicity of the overall composite. Additionally, histological analysis found no observable tissue damage in the skin or vital organs in mice, following multiple subcutaneous administrations. This study shows that ZIF-based protein composites are strong candidates for improved preservation of proteinaceous drugs, are biocompatible, and capable of controlling the release and adsorption of drugs in vivo.</p></div></div></div>

One-step controlled synthesis of anisotropic gold nanostructures with aniline as the reductant in aqueous solution

2007 ◽  
Vol 309 (2) ◽  
pp. 518-523 ◽  
Author(s):  
Zhirui Guo ◽  
Yu Zhang ◽  
Lan Huang ◽  
Meng Wang ◽  
Jing Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Gold Nanostructures ◽  
Controlled Synthesis ◽  
One Step

scholarly journals Persistent luminescence nanoparticles for cancer theranostics application

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Nian Liu ◽  
Xiao Chen ◽  
Xia Sun ◽  
Xiaolian Sun ◽  
Junpeng Shi
Keyword(s):  
Uv Light ◽  
Combined Therapy ◽  
Tumor Therapy ◽  
High Sensitivity ◽  
Persistent Luminescence ◽  
Therapeutic Drugs ◽  
High Penetration ◽  
Recent Developments ◽  
Cancer Theranostics

AbstractPersistent luminescence nanoparticles (PLNPs) are unique optical materials that emit afterglow luminescence after ceasing excitation. They exhibit unexpected advantages for in vivo optical imaging of tumors, such as autofluorescence-free, high sensitivity, high penetration depth, and multiple excitation sources (UV light, LED, NIR laser, X-ray, and radiopharmaceuticals). Besides, by incorporating other functional molecules, such as photosensitizers, photothermal agents, or therapeutic drugs, PLNPs are also widely used in persistent luminescence (PersL) imaging-guided tumor therapy. In this review, we first summarize the recent developments in the synthesis and surface functionalization of PLNPs, as well as their toxicity studies. We then discuss the in vivo PersL imaging and multimodal imaging from different excitation sources. Furthermore, we highlight PLNPs-based cancer theranostics applications, such as fluorescence-guided surgery, photothermal therapy, photodynamic therapy, drug/gene delivery and combined therapy. Finally, future prospects and challenges of PLNPs in the research of translational medicine are also discussed.

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