Significantly Accelerated Osteoblast Cell Growth on TiO2/SrHA Composite Mediated by Phenolic Compounds (BHM) from Hippocampus kuda Bleeler

2018 ◽  
Vol 10 (36) ◽  
pp. 30214-30226 ◽  
Author(s):  
Qiong Yuan ◽  
Lei He ◽  
Zhong-Ji Qian ◽  
Chunxia Zhou ◽  
Pengzhi Hong ◽  
...  
2002 ◽  
Vol 8 (S02) ◽  
pp. 758-759
Author(s):  
S. Iadarola ◽  
A. Crugnola ◽  
R. Joshi ◽  
J. Tessier ◽  
C. Sung

2016 ◽  
Vol 15 (7) ◽  
pp. 704-712 ◽  
Author(s):  
Udesh Dhawan ◽  
Hsu-An Pan ◽  
Ying Hao Chu ◽  
Guewha S. Huang ◽  
Po Chun Chen ◽  
...  

RSC Advances ◽  
2020 ◽  
Vol 10 (31) ◽  
pp. 18222-18230
Author(s):  
Luis M. De Leon-Rodriguez ◽  
Young-Eun Park ◽  
Dorit Naot ◽  
David S. Musson ◽  
Jillian Cornish ◽  
...  

Self-assembling peptide H4LMAX-RGDS hydrogels, designed to enhance bone regeneration, are cytocompatible and capable of delivering the bone anabolic factor lactoferrin to increase osteoblast cell number.


2006 ◽  
Vol 78A (1) ◽  
pp. 97-103 ◽  
Author(s):  
Seunghan Oh ◽  
Chiara Daraio ◽  
Li-Han Chen ◽  
Thomas R. Pisanic ◽  
Rita R. Fiñones ◽  
...  

2010 ◽  
Vol 391 (1) ◽  
pp. 669-673 ◽  
Author(s):  
Claire Martin ◽  
Jean-Michel Lafosse ◽  
Bernard Malavaud ◽  
Olivier Cuvillier

2009 ◽  
Vol 20 (14) ◽  
pp. 2055-2072 ◽  
Author(s):  
Keith Gordon ◽  
Biswajit Sannigrahi ◽  
Paul Mcgeady ◽  
X. Q. Wang ◽  
Juana Mendenhall ◽  
...  

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Chihiro Ito ◽  
Takuya Matsui ◽  
Eri Noda ◽  
Nijsiri Ruangrungsi ◽  
Masataka Itoigawa

Study of the chemical constituents of the stems of Garcinia schomburgkiana Pierre (Guttiferae), collected in Thailand, led to the isolation and identification of five known compounds and two new biphenyl derivatives, schomburgbiphenyl A (1) and B (2). Six phenolic compounds isolated from this plant were screened for their cell growth inhibition activity using several human leukemia cell lines. One compound, oblongifolin C (7), showed significant cytotoxic activity towards Jurkat, NALM6, K562 and HPB-ALL cells.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Luciana Arantes Dantas ◽  
Paula Sperotto Alberto Faria ◽  
Bruno Matheus Mendes Dário ◽  
Ana Luíza Martins Arantes ◽  
Fabiano Guimarães Silva ◽  
...  

AbstractBelonging to the Brazilian flora, the species Hancornia speciosa (Gomes), known as mangabeira, has bioactive compounds of interest, such as flavonoids, xanthones, and proanthocyanidins. The objective of this study was to determine how the supplementation of sugars in culture medium affects the osmotic potential of the medium, as well as its influence on cell growth and on the concentration of phenolic compounds. For this purpose, after 90 days of subculture, 20 mL aliquots of the cultures were added to flasks containing 20 mL of medium with different sugars (glucose, fructose, sucrose, mannitol, and sorbitol) under a 16-h photoperiod with a spectral range between 400 and 700 nm of photosynthetically active radiation (45–55 μmol m−2 s−1) in a shaker at 110 rpm. After 30 days, the pH, electrical conductivity, osmotic potential, biomass accumulation, and concentrations of phenolic compounds were evaluated. Regardless of their concentration in the medium, the sugars sorbitol and mannitol provided more unfavorable conditions for water absorption at the cellular level, reducing the water potential of the medium. Sucrose favored greater water absorption and biomass accumulation. Among the various sugar concentrations, 3% (30 g/L) sucrose or glucose improved the accumulation of fresh and dry cell weight and the production of polyphenols such as chlorogenic acid, epicatechin, rosmarinic acid, hesperidin, rutin, and quercetin. In addition, they resulted in a higher osmotic potential of the medium and larger cells than other carbon sources. Despite the differences in cell size, no culture conditions compromised cell survival.


2021 ◽  
Author(s):  
Luciana Arantes Dantas ◽  
Paula Sperotto Alberto Faria ◽  
Bruno Matheus Mendes Dário ◽  
Ana Luíza Martins Arantes ◽  
Fabiano Guimarães Silva ◽  
...  

Abstract Belonging to the Brazilian flora, the species Hancornia speciosa (Gomes), known as mangabeira, has bioactive compounds of interest, such as flavonoids, xanthones, and proanthocyanidins. The objective of this study was to determine how the supplementation of sugars in culture medium affects the osmotic potential of the medium, as well as its influence on cell growth and on the concentration of phenolic compounds. For this purpose, after 90 days of subculture, 20 ml aliquots of the cultures were added to flasks containing 20 ml of medium with different sugars (glucose, fructose, sucrose, mannitol, and sorbitol) under a 16-h photoperiod with a spectral range between 400 and 700 nm of photosynthetically active radiation (45-55 μmol m -2 s -1 ) in a shaker at 110 rpm. After 30 days, the pH, electrical conductivity, osmotic potential, biomass accumulation, and concentrations of phenolic compounds were evaluated. Regardless of their concentration in the medium, the sugars sorbitol and mannitol provided more unfavorable conditions for water absorption at the cellular level, reducing the water potential of the medium. Sucrose favored greater water absorption and biomass accumulation. Among the various sugar concentrations, 3% (30 g/L) sucrose or glucose improved the accumulation of fresh and dry cell weight and the production of polyphenols such as chlorogenic acid, epicatechin, rosmarinic acid, hesperidin, rutin, and quercetin. In addition, they resulted in a higher osmotic potential of the medium and larger cells than other carbon sources. Despite the differences in cell size, no culture conditions compromised cell survival.


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