Self-Quenched Metal–Organic Particles as Dual-Mode Therapeutic Agents for Photoacoustic Imaging-Guided Second Near-Infrared Window Photochemotherapy

2018 ◽  
Vol 10 (30) ◽  
pp. 25203-25212 ◽  
Author(s):  
Da Zhang ◽  
Hao Xu ◽  
Xiaolong Zhang ◽  
Yubin Liu ◽  
Ming Wu ◽  
...  
2021 ◽  
Vol 93 (6) ◽  
pp. 3189-3195
Author(s):  
Jiayingzi Wu ◽  
Liyan You ◽  
Saadia T. Chaudhry ◽  
Jiazhi He ◽  
Ji-Xin Cheng ◽  
...  

2017 ◽  
Vol 5 (9) ◽  
pp. 1772-1778 ◽  
Author(s):  
Xiangjun Chen ◽  
Manjie Zhang ◽  
Shengnan Li ◽  
Lu Li ◽  
Lingyu Zhang ◽  
...  

A facile route was developed to fabricate PPy@MOF for dual-mode magnetic resonance/photoacoustic imaging and synergistic chemo-photothermal therapy.


RSC Advances ◽  
2021 ◽  
Vol 11 (20) ◽  
pp. 12022-12029
Author(s):  
Zhuo Jia ◽  
Rong Dai ◽  
Ziliang Zheng ◽  
Yufei Qin ◽  
Ailin Duan ◽  
...  

We have developed a novel nanotheranostic platform (HC-AB NPs) via loading ammonia borane (AB) into hollow carbon nanoparticles (HCs) for NIR-II photoacoustic (PA) imaging-guided NIR-II hydrogenothermal therapy.


2019 ◽  
Vol 24 (04) ◽  
pp. 1 ◽  
Author(s):  
Paul Kumar Upputuri ◽  
Manojit Pramanik

Author(s):  
Yaxi Li ◽  
Hongli Zhou ◽  
Renzhe Bi ◽  
Xiuting Li ◽  
Menglei Zha ◽  
...  

Fluorescence imaging in the second near-infrared window (NIR-II) has been an emerging technique in diverse in vivo applications with high sensitivity/resolution and deep tissue penetration. To date, the designing principle...


2019 ◽  
Vol 7 (2) ◽  
pp. 472-479 ◽  
Author(s):  
Kai Huang ◽  
Yifan Zhang ◽  
Jing Lin ◽  
Peng Huang

The use of nanomaterials as contrast agents for photoacoustic imaging in the NIR-II window enables enhanced imaging quality with deeper tissue penetration.


2019 ◽  
Vol 43 (23) ◽  
pp. 8835-8851 ◽  
Author(s):  
Xiaoguang Ge ◽  
Qinrui Fu ◽  
Lin Bai ◽  
Bin Chen ◽  
Renjie Wang ◽  
...  

This review summarizes the recent progress of PA imaging and PTT agents in the second NIR window.


Nano Letters ◽  
2017 ◽  
Vol 17 (8) ◽  
pp. 4964-4969 ◽  
Author(s):  
Yuyan Jiang ◽  
Paul Kumar Upputuri ◽  
Chen Xie ◽  
Yan Lyu ◽  
Lulu Zhang ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Yun Zhou ◽  
Bixia Lin ◽  
Kai Li ◽  
Yufeng Zhao ◽  
Zhuo Sun ◽  
...  

At present, the clinical diagnosis of and treatment methods for hepatic carcinoma still fail to fully meet the needs of patients. The integrated theranostic system, in which functional materials are used to load different active molecules, created a new developmental direction for the combination treatment of hepatic carcinoma, realizing the synchronization of diagnosis and treatment. In this study, polydopamine (PDA), which has the functions of self-assembly, encapsulation, photothermal conversion, and photoacoustic interaction, was used as the carrier material. The IR780, a near-infrared fluorescence imaging (NIFI), photoacoustic imaging (PAI), and photothermal therapy (PTT) agent, and paclitaxel (PTX), a broad-spectrum chemotherapy drug, were selected to build the NIF/PA dual-mode imaging and PTT/chemo synergistic theranostic nanoparticles (DIST NPs). The DIST NPs have a 103.4 ± 13.3 nm particle size, a weak negative charge on the surface, good colloidal stability, slow and controlled drug release, and high photothermal conversion ability. The experiments results showed that the DIST NPs have a long circulation in vivo, high bioavailability, high biocompatibility, and low effective dose. DIST NPs showed an excellent NIFI/PAI dual-mode imaging and significant synergistic antitumor effect in hepatic carcinoma models. DIST NPs met the initial design requirements. A set of fast and low-cost preparation methods was established. This study provides an experimental basis for the development of new clinical theranostic methods for hepatic carcinoma.


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