Highly Photostable Near-IR-Excitation Upconversion Nanocapsules Based on Triplet–Triplet Annihilation for in Vivo Bioimaging Application

2018 ◽  
Vol 10 (12) ◽  
pp. 9883-9888 ◽  
Author(s):  
Qian Liu ◽  
Ming Xu ◽  
Tianshe Yang ◽  
Bo Tian ◽  
Xinglin Zhang ◽  
...  
Keyword(s):  
Near Ir ◽  
Triplet Triplet Annihilation

scholarly journals Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy

2019 ◽  
Vol 116 (6) ◽  
pp. 1968-1973 ◽  
Author(s):  
Yue Sun ◽  
Feng Ding ◽  
Zhixuan Zhou ◽  
Chonglu Li ◽  
Maoping Pu ◽  
...  
Keyword(s):  
Fluorescent Imaging ◽  
Tumor Diagnosis ◽  
In Vivo Studies ◽  
Passive Targeting ◽  
Near Ir ◽  
Enhanced Permeability And Retention ◽  
Targeting Ability ◽  
Methoxy Polyethylene Glycol ◽  
Growth Of Tumor

Fluorescent theranostics probes at the second near-IR region (NIR-II; 1.0–1.7 µm) are in high demand for precise theranostics that minimize autofluorescence, reduce photon scattering, and improve the penetration depth. Herein, we designed and synthesized an NIR-II theranostic nanoprobe 1 that incorporates a Pt(II) metallacycle 2 and an organic molecular dye 3 into DSPE-mPEG5000 (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000]). This design endows 1 with good photostability and passive targeting ability. Our studies show that 1 accurately diagnoses cancer with high resolution and selectively delivers the Pt(II) metallacycle to tumor regions via an enhanced permeability and retention effect. In vivo studies reveal that 1 efficiently inhibits the growth of tumor with minimal side effects. At the same time, improved fluorescent imaging quality and signal-to-noise ratios are shown due to the long emission wavelengths. These studies demonstrate that 1 is a potential theranostic platform for tumor diagnosis and treatment in the NIR-II region.

In vivo flow cytometry and time-resolved near-IR angiography and lymphography

2007 ◽  
Author(s):  
Ekaterina I. Galanzha ◽  
Valery V. Tuchin ◽  
Robert W. Brock ◽  
Vladimir P. Zharov
Keyword(s):  
Flow Cytometry ◽  
Time Resolved ◽  
Near Ir

Near-IR-Absorbing Gold Nanoframes with Enhanced Physiological Stability and Improved Biocompatibility for In Vivo Biomedical Applications

2017 ◽  
Vol 9 (4) ◽  
pp. 3873-3884 ◽  
Author(s):  
Liying Wang ◽  
Yunching Chen ◽  
Hsin Yao Lin ◽  
Yung-Te Hou ◽  
Ling-Chu Yang ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Near Ir

Targeted near-IR hybrid magnetic nanoparticles for in vivo cancer therapy and imaging

2013 ◽  
Vol 9 (5) ◽  
pp. 702-711 ◽  
Author(s):  
Dickson K. Kirui ◽  
Ildar Khalidov ◽  
Yi Wang ◽  
Carl A. Batt
Keyword(s):  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Near Ir

One-step synthesis of silver nanoshells with bumps for highly sensitive near-IR SERS nanoprobes

2014 ◽  
Vol 2 (28) ◽  
pp. 4415-4421 ◽  
Author(s):  
Homan Kang ◽  
Jin-Kyoung Yang ◽  
Mi Suk Noh ◽  
Ahla Jo ◽  
Sinyoung Jeong ◽  
...  
Keyword(s):  
Cell Tracking ◽  
Live Animal ◽  
Near Ir ◽  
Highly Sensitive ◽  
One Step ◽  
Silver Nanoshells

Based on AgNSs with bump-structures, the NIR active, ultrasensitive, and biocompatible SERS probes were developed and applied forin vivocell tracking in a live animal.

Texaphyrin sensitized near-IR-to-visible photon upconversion

2014 ◽  
Vol 13 (5) ◽  
pp. 813-819 ◽  
Author(s):  
Fan Deng ◽  
Wenfang Sun ◽  
Felix N. Castellano
Keyword(s):  
Yellow Fluorescence ◽  
Near Ir ◽  
Nir Absorption ◽  
Visible Photon ◽  
Triplet Triplet Annihilation

Near-IR (NIR) absorption from a Cd(ii) texaphyrin (TXP) has been successfully coupled with rubrene triplet acceptors/annihilators in vacuum degassed dichloromethane to upconvert NIR (670–800 nm) incident photons into yellow fluorescence through sensitized triplet–triplet annihilation.

scholarly journals Multimeric Near IR–MR Contrast Agent for Multimodal In Vivo Imaging

2015 ◽  
Vol 137 (28) ◽  
pp. 9108-9116 ◽  
Author(s):  
Victoria S. R. Harrison ◽  
Christiane E. Carney ◽  
Keith W. MacRenaris ◽  
Emily A. Waters ◽  
Thomas J. Meade
Keyword(s):  
Contrast Agent ◽  
In Vivo Imaging ◽  
Near Ir

scholarly journals Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression

2015 ◽  
Vol 26 (8) ◽  
pp. 1513-1518 ◽  
Author(s):  
Eunha Kim ◽  
Katherine S. Yang ◽  
Rainer H. Kohler ◽  
John M. Dubach ◽  
Hannes Mikula ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Near Ir
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