scholarly journals Direct Metal Writing and Precise Positioning of Gold Nanoparticles within Microfluidic Channels for SERS Sensing of Gaseous Analytes

2017 ◽  
Vol 9 (45) ◽  
pp. 39584-39593 ◽  
Author(s):  
Mian Rong Lee ◽  
Hiang Kwee Lee ◽  
Yijie Yang ◽  
Charlynn Sher Lin Koh ◽  
Chee Leng Lay ◽  
...  
2018 ◽  
Vol 5 (9) ◽  
pp. 095003
Author(s):  
Richard E Darienzo ◽  
Kathryn Karius ◽  
Niveditha Obla ◽  
Chung-Chueh Chang ◽  
Tatsiana Mironava

2020 ◽  
Vol 4 (11) ◽  
pp. 3240-3250
Author(s):  
Xi Mao ◽  
Zhengping Tan ◽  
Wei Lan ◽  
Huayang Wang ◽  
Haiying Tan ◽  
...  

Recently, self-assembly of polymer-tethered inorganic nanoparticles (NPs) in microfluidic chips has been employed as an effective approach to fabricate novel assemblies.


2021 ◽  
Vol 12 ◽  
Author(s):  
Alessandro Verde ◽  
Maria Mangini ◽  
Stefano Managò ◽  
Chiara Tramontano ◽  
Ilaria Rea ◽  
...  

Engineered gold nanoparticles (AuNPs) find application in several fields related to human activities (i.e., food and cosmetic industry or water purification) including medicine, where they are employed for diagnosis, drug delivery and cancer therapy. As for any material/reagent for human use, the safety of AuNPs needs accurate evaluation. AuNPs are prone to contamination by bacterial endotoxin (lipopolysaccharide, LPS), a potent elicitor of inflammatory responses in mammals. It is therefore important, when assessing AuNP immunosafety and immune-related effects, to discriminate between inflammatory effects intrinsic to the NPs from those caused by an undeliberate and undetected LPS contamination. Detection of LPS contamination in AuNP preparations poses different problems when using the current LPS detection assays, given the general interference of NPs, similar to other particulate agents, with the assay reagents and endpoints. This leads to time-consuming search for optimal assay conditions for every NP batch, with unpredictable results, and to the use in parallel of different assays, each with its weaknesses and unpredictability. Thus, the development of highly sensitive, quantitative and accurate assays able to detect of LPS on AuNPs is very important, in view of their medical applications. Surface-enhanced Raman spectroscopy (SERS) is a label-free, sensitive, chemical-specific, nondestructive and fast technique that can be used to directly obtain molecular fingerprint information and a quantitative analysis of LPS adsorbed on AuNPs. Within this study, we describe the use of SERS for the label-free identification and quantitative evaluation - down to few attograms - of the LPS adsorbed on the surface of 50 nm AuNPs. We thus propose SERS as an efficient tool to detect LPS on the AuNP surface, and as the basis for the development of a new sensitive and specific LPS-detection sensor based on the use of AuNPs and SERS.


2019 ◽  
Vol 11 (40) ◽  
pp. 5089-5097 ◽  
Author(s):  
Amin Zhang ◽  
Jie Chang ◽  
Yunsheng Chen ◽  
Zhicheng Huang ◽  
Gabriel Alfranca ◽  
...  

Clean SERS substrates could be prepared without using polymer stabilizers and highly toxic reducing agents, and they play a pivotal role in trace amount detection.


Nano Research ◽  
2021 ◽  
Author(s):  
Dongzhen Chen ◽  
Liang Zhang ◽  
Pan Ning ◽  
Haozhi Yuan ◽  
Yu Zhang ◽  
...  

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
N Fekete-Drimusz ◽  
J de la Roche ◽  
F Vondran ◽  
CL Sajti ◽  
MP Manns ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document