Encapsulation of Gadolinium Oxide Nanoparticle (Gd2O3) Contrasting Agents in PAMAM Dendrimer Templates for Enhanced Magnetic Resonance Imaging in Vivo

2017 ◽  
Vol 9 (8) ◽  
pp. 6782-6795 ◽  
Author(s):  
Shewaye Lakew Mekuria ◽  
Tilahun Ayane Debele ◽  
Hsieh-Chih Tsai
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Pamam Dendrimer ◽  
Gadolinium Oxide ◽  
Resonance Imaging ◽  
Oxide Nanoparticle

Ligand-free gadolinium oxide for in vivo T1-weighted magnetic resonance imaging

2013 ◽  
Vol 15 (29) ◽  
pp. 12235 ◽  
Author(s):  
Ningqi Luo ◽  
Xiumei Tian ◽  
Chuan Yang ◽  
Jun Xiao ◽  
Wenyong Hu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Gadolinium Oxide ◽  
Resonance Imaging ◽  
Ligand Free ◽  
Weighted Magnetic Resonance Imaging

scholarly journals Stable and non-toxic ultrasmall gadolinium oxide nanoparticle colloids (coating material = polyacrylic acid) as high-performance T1 magnetic resonance imaging contrast agents

RSC Advances ◽  
2018 ◽  
Vol 8 (6) ◽  
pp. 3189-3197 ◽  
Author(s):  
Xu Miao ◽  
Son Long Ho ◽  
Tirusew Tegafaw ◽  
Hyunsil Cha ◽  
Yongmin Chang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Polyacrylic Acid ◽  
High Performance ◽  
Gadolinium Oxide ◽  
Coating Material ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Contrast ◽  
Oxide Nanoparticle

Stable and non-toxic ultrasmall Gd2O3 nanoparticle colloids as high-performance T1 MRI-CA were developed.

Monitoring stem cell migration in the nervous system by in vivo magnetic resonance imaging

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S692-S692
Author(s):  
Mathias Hoehn ◽  
Uwe Himmelreich ◽  
Ralph Weber ◽  
Pedro Ramos-Cabrer ◽  
Susanne Wegener ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Nervous System ◽  
Stem Cell ◽  
Cell Migration ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Stem Cell Migration

Supramolecular Enhancement of Aminoxyl ORCA Contrast Agents

2019 ◽  
Author(s):  
Hamilton Lee ◽  
Jenica Lumata ◽  
Michael A. Luzuriaga ◽  
Candace Benjamin ◽  
Olivia Brohlin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Side Effects ◽  
Magnetic Resonance ◽  
Tobacco Mosaic Virus ◽  
Contrast Agents ◽  
Single Molecule ◽  
Organic Radical ◽  
Resonance Imaging ◽  
Physiological Conditions

<div><div><div><p>Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo. We further over came the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.</p></div></div></div>

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