Novel Platform of Cardiomyocyte Culture and Coculture via Fibroblast-Derived Matrix-Coupled Aligned Electrospun Nanofiber

2016 ◽  
Vol 9 (1) ◽  
pp. 224-235 ◽  
Author(s):  
Muhammad Suhaeri ◽  
Ramesh Subbiah ◽  
Su-Hyun Kim ◽  
Chong-Hyun Kim ◽  
Seung Ja Oh ◽  
...  
Keyword(s):  
Electrospun Nanofiber ◽  
Cardiomyocyte Culture

Conducting and Biopolymer Based Electrospun Nanofiber Membranes for Wound Healing Applications

2016 ◽  
Vol 12 (2) ◽  
pp. 220-227 ◽  
Author(s):  
Mohammad R. Karim ◽  
Abdurahman Al-Ahmari ◽  
M.A. Dar ◽  
M.O. Aijaz ◽  
M.L. Mollah ◽  
...  
Keyword(s):  
Wound Healing ◽  
Electrospun Nanofiber ◽  
Nanofiber Membranes

scholarly journals Conformal Fabrication of an Electrospun Nanofiber Mat on a 3D Ear Cartilage-Shaped Hydrogel Collector Based on Hydrogel-Assisted Electrospinning

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jin Yeong Song ◽  
Hyun Il Ryu ◽  
Jeong Myeong Lee ◽  
Seong Hwan Bae ◽  
Jae Woo Lee ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Electrospun Nanofibers ◽  
Cell Delivery ◽  
Complex Geometries ◽  
Two Dimensional ◽  
Uniform Thickness ◽  
Electrospun Nanofiber ◽  
Electrospinning Technique ◽  
Ear Cartilage ◽  
Focused Electric Field

AbstractElectrospinning is a common and versatile process to produce nanofibers and deposit them on a collector as a two-dimensional nanofiber mat or a three-dimensional (3D) macroscopic arrangement. However, 3D electroconductive collectors with complex geometries, including protruded, curved, and recessed regions, generally caused hampering of a conformal deposition and incomplete covering of electrospun nanofibers. In this study, we suggested a conformal fabrication of an electrospun nanofiber mat on a 3D ear cartilage-shaped hydrogel collector based on hydrogel-assisted electrospinning. To relieve the influence of the complex geometries, we flattened the protruded parts of the 3D ear cartilage-shaped hydrogel collector by exploiting the flexibility of the hydrogel. We found that the suggested fabrication technique could significantly decrease an unevenly focused electric field, caused by the complex geometries of the 3D collector, by alleviating the standard deviation by more than 70% through numerical simulation. Furthermore, it was experimentally confirmed that an electrospun nanofiber mat conformally covered the flattened hydrogel collector with a uniform thickness, which was not achieved with the original hydrogel collector. Given that this study established the conformal electrospinning technique on 3D electroconductive collectors, it will contribute to various studies related to electrospinning, including tissue engineering, drug/cell delivery, environmental filter, and clothing.

scholarly journals Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

2021 ◽  
Vol 11 (15) ◽  
pp. 6929
Author(s):  
Ewin Tanzli ◽  
Andrea Ehrmann
Keyword(s):  
Tissue Engineering ◽  
Cell Growth ◽  
Polymer Blends ◽  
Mammalian Cells ◽  
Biological Properties ◽  
Specific Substrate ◽  
Electrospun Nanofiber ◽  
Materials Used ◽  
Nanofiber Mats ◽  
Surface Morphologies

In biotechnology, the field of cell cultivation is highly relevant. Cultivated cells can be used, for example, for the development of biopharmaceuticals and in tissue engineering. Commonly, mammalian cells are grown in bioreactors, T-flasks, well plates, etc., without a specific substrate. Nanofibrous mats, however, have been reported to promote cell growth, adhesion, and proliferation. Here, we give an overview of the different attempts at cultivating mammalian cells on electrospun nanofiber mats for biotechnological and biomedical purposes. Starting with a brief overview of the different electrospinning methods, resulting in random or defined fiber orientations in the nanofiber mats, we describe the typical materials used in cell growth applications in biotechnology and tissue engineering. The influence of using different surface morphologies and polymers or polymer blends on the possible application of such nanofiber mats for tissue engineering and other biotechnological applications is discussed. Polymer blends, in particular, can often be used to reach the required combination of mechanical and biological properties, making such nanofiber mats highly suitable for tissue engineering and other biotechnological or biomedical cell growth applications.

scholarly journals Electrospun Nanofibers for Sensing and Biosensing Applications—A Review

2021 ◽  
Vol 22 (12) ◽  
pp. 6357
Author(s):  
Kinga Halicka ◽  
Joanna Cabaj
Keyword(s):  
High Surface ◽  
High Surface Area ◽  
Toxic Metal ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Clinical Diagnostics ◽  
Loading Capacity ◽  
Electrospun Nanofiber ◽  
Sensing Platforms ◽  
Different Types

Sensors and biosensors have found applications in many areas, e.g., in medicine and clinical diagnostics, or in environmental monitoring. To expand this field, nanotechnology has been employed in the construction of sensing platforms. Because of their properties, such as high surface area to volume ratio, nanofibers (NFs) have been studied and used to develop sensors with higher loading capacity, better sensitivity, and faster response time. They also allow to miniaturize designed platforms. One of the most commonly used techniques of the fabrication of NFs is electrospinning. Electrospun NFs can be used in different types of sensors and biosensors. This review presents recent studies concerning electrospun nanofiber-based electrochemical and optical sensing platforms for the detection of various medically and environmentally relevant compounds, including glucose, drugs, microorganisms, and toxic metal ions.

scholarly journals Multifunctional Fibroblasts Enhanced via Thermal and Freeze-Drying Post-treatments of Aligned Electrospun Nanofiber Membranes

2021 ◽  
Vol 3 (1) ◽  
pp. 26-37
Author(s):  
Ya Li ◽  
Qian Shen ◽  
Jing Shen ◽  
Xinbo Ding ◽  
Tao Liu ◽  
...  
Keyword(s):  
Freeze Drying ◽  
Electrospun Nanofiber ◽  
Nanofiber Membranes
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