scholarly journals Long-Term Stable Adhesion for Conducting Polymers in Biomedical Applications: IrOx and Nanostructured Platinum Solve the Chronic Challenge

2016 ◽  
Vol 9 (1) ◽  
pp. 189-197 ◽  
Author(s):  
Christian Boehler ◽  
Felix Oberueber ◽  
Sabine Schlabach ◽  
Thomas Stieglitz ◽  
Maria Asplund
Keyword(s):  
Conducting Polymers ◽  
Biomedical Applications

Biomedical Applications of Organic Conducting Polymers

2019 ◽  
pp. 783-812
Author(s):  
Alexander R. Harris ◽  
Paul J. Molino ◽  
Caiyun Wang ◽  
Gordon G. Wallace ◽  
Zhilian Yue
Keyword(s):  
Conducting Polymers ◽  
Biomedical Applications

scholarly journals Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

2020 ◽  
Vol 11 (4) ◽  
pp. 71 ◽  
Author(s):  
John H. T. Luong ◽  
Tarun Narayan ◽  
Shipra Solanki ◽  
Bansi D. Malhotra
Keyword(s):  
Drug Delivery ◽  
Conducting Polymers ◽  
Biomedical Applications ◽  
Carbon Materials ◽  
Functional Materials ◽  
Glucose Sensing ◽  
Research Trends ◽  
Future Research ◽  
Electrochemical Biosensing ◽  
And Performance

Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.

Biomedical Perspectives of Polyaniline Based Biosensors

2013 ◽  
Vol 810 ◽  
pp. 173-216 ◽  
Author(s):  
Amir Al-Ahmed ◽  
Haitham M. Bahaidarah ◽  
Mohammad A. Jafar Mazumder
Keyword(s):  
Electron Transfer ◽  
Conducting Polymers ◽  
Biomedical Applications ◽  
Catalytic Properties ◽  
Direct Electron Transfer ◽  
Review Article ◽  
Direct Communication ◽  
Electrically Conducting ◽  
Electrically Conducting Polymers ◽  
Significant Attention

Electrically conducting polymers (ECPs) are finding applications in various fields of science owing to their fascinating characteristic properties such as binding molecules, tuning their properties, direct communication to produce a range of analytical signals and new analytical applications. Polyaniline (PANI) is one such ECP that has been extensively used and investigated over the last decade for direct electron transfer leading towards fabrication of mediator-less biosensors. In this review article, significant attention has been paid to the various polymerization techniques of polyaniline as a transducer material, and their use in enzymes/biomolecules immobilization methods to study their bio-catalytic properties as a biosensor for potential biomedical applications.

Electrospun polymeric micro/nanofibrous scaffolds for long-term drug release and their biomedical applications

2017 ◽  
Vol 22 (9) ◽  
pp. 1351-1366 ◽  
Author(s):  
Qiang Zhang ◽  
Yingchun Li ◽  
Zhi Yuan (William) Lin ◽  
Kenneth K.Y. Wong ◽  
Min Lin ◽  
...  
Keyword(s):  
Drug Release ◽  
Biomedical Applications ◽  
Nanofibrous Scaffolds

Erodible Conducting Polymers for Potential Biomedical Applications

2002 ◽  
Vol 41 (1) ◽  
pp. 141-144 ◽  
Author(s):  
Alexander N. Zelikin ◽  
David M. Lynn ◽  
Jian Farhadi ◽  
Ivan Martin ◽  
Venkatram Shastri ◽  
...  
Keyword(s):  
Conducting Polymers ◽  
Biomedical Applications

Comparison of immunomodulatory properties of purified lactoferrin, lactoperoxidase and β-casein in sheep

1998 ◽  
Vol 65 (4) ◽  
pp. 697-701 ◽  
Author(s):  
CHUN W. WONG ◽  
DENNIS L. WATSON ◽  
GEOFFREY O. REGESTER ◽  
GEOFFREY W. SMITHERS
Keyword(s):  
Biomedical Applications ◽  
Bovine Milk ◽  
Milk Proteins ◽  
Biologically Active ◽  
Immunological Effects ◽  
Bovine Milk Proteins ◽  
Proteins And Peptides

Bovine milk contains a variety of proteins and peptides that are biologically active (Ogra & Ogra, 1978; Duncan & McArthur, 1981; Newby et al. 1982; Juto, 1985; Stoeck et al. 1989; Mincheva-Nilsson et al. 1990; Watson, 1990; Barta et al. 1991; Politis et al. 1991; Fiat et al. 1993). Our laboratory has a long-term interest in some purified milk proteins, particularly lactoferrin (LF), lactoperoxidase (LP) and β-casein (β-CN), which have been shown to be immunologically significant. Some of our recent studies on these bovine milk proteins, particularly β-CN, indicated that their in vitro immunological effects did not always parallel their in vivo activities (Wong et al. 1996a, b; 1997a, b). This study was designed to investigate and compare the capacity of these purified bovine milk proteins to modulate a range of components that are vital to in vivo immune responses in sheep, with a view to providing further information on their potential in biomedical applications. To achieve this objective, a sensitive lymphatic cannulation model was employed that allows in vivo immune components and their functions to be measured in lymph collected under physiological conditions.

scholarly journals Long term biotransformation and toxicity of dimercaptosuccinic acid-coated magnetic nanoparticles support their use in biomedical applications

2013 ◽  
Vol 171 (2) ◽  
pp. 225-233 ◽  
Author(s):  
Raquel Mejías ◽  
Lucía Gutiérrez ◽  
Gorka Salas ◽  
Sonia Pérez-Yagüe ◽  
Teresa M. Zotes ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Dimercaptosuccinic Acid

Conducting polymers for neural interfaces: Challenges in developing an effective long-term implant

Biomaterials ◽  
2008 ◽  
Vol 29 (24-25) ◽  
pp. 3393-3399 ◽  
Author(s):  
Rylie A. Green ◽  
Nigel H. Lovell ◽  
Gordon G. Wallace ◽  
Laura A. Poole-Warren
Keyword(s):  
Conducting Polymers ◽  
Neural Interfaces

scholarly journals Stem cell-laden hydrogel bioink for generation of high resolution and fidelity engineered tissues with complex geometries

2021 ◽  
Author(s):  
Oju Jeon ◽  
Yu Bin Lee ◽  
Sang Jin Lee ◽  
Nazilya Guliyeva ◽  
Joanna Lee ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Resolution ◽  
Biomedical Applications ◽  
Human Mesenchymal Stem Cells ◽  
Complex Geometries ◽  
Complex Structures ◽  
Self Healing ◽  
3D Bioprinting ◽  
Healing Property

Recently, 3D bioprinting has been explored as a promising technology for biomedical applications with the potential to create complex structures with precise features. Cell encapsulated hydrogels composed of materials such as gelatin, collagen, hyaluronic acid, alginate and polyethylene glycol have been widely used as bioinks for 3D bioprinting. However, since most hydrogel-based bioinks may not allow rapid stabilization immediately after 3D bioprinting, achieving high resolution and fidelity to the intended architecture is a common challenge in 3D bioprinting of hydrogels. In this study, we have utilized shear-thinning and self-healing ionically crosslinked oxidized and methacrylated alginates (OMAs) as a bioink, which can be rapidly gelled by its self-healing property after bioprinting and further stabilized via secondary crosslinking. It was successfully demonstrated that stem cell-laden calcium-crosslinked OMA hydrogels can be bioprinted into complicated 3D tissue structures with both high resolution and fidelity. Additional photocrosslinking enables long-term culture of 3D bioprinted constructs for formation of functional tissue by differentiation of encapsulated human mesenchymal stem cells.

scholarly journals ROS-Based Nanoparticles for Atherosclerosis Treatment

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6921
Author(s):  
Xin Hu ◽  
Pengxuan Zhao ◽  
Yongping Lu ◽  
Yani Liu
Keyword(s):  
Biomedical Applications ◽  
Developed Countries ◽  
Arterial Disease ◽  
Oxygen Species ◽  
Future Perspectives ◽  
Early Prevention ◽  
Adverse Side Effects ◽  
Diagnostic Applications ◽  
Atherosclerosis Treatment

Atherosclerosis (AS), a chronic arterial disease, is the leading cause of death in western developed countries. Considering its long-term asymptomatic progression and serious complications, the early prevention and effective treatment of AS are particularly important. The unique characteristics of nanoparticles (NPs) make them attractive in novel therapeutic and diagnostic applications, providing new options for the treatment of AS. With the assistance of reactive oxygen species (ROS)-based NPs, drugs can reach specific lesion areas, prolong the therapeutic effect, achieve targeted controlled release and reduce adverse side effects. In this article, we reviewed the mechanism of AS and the generation and removal strategy of ROS. We further discussed ROS-based NPs, and summarized their biomedical applications in scavenger and drug delivery. Furthermore, we highlighted the recent advances, challenges and future perspectives of ROS-based NPs for treating AS.

Sign in / Sign up

Export Citation Format

Share Document