Superparamagnetic Iron Oxide Nanoparticles Modified with Tween 80 Pass through the Intact Blood–Brain Barrier in Rats under Magnetic Field

2016 ◽  
Vol 8 (18) ◽  
pp. 11336-11341 ◽  
Author(s):  
Yinping Huang ◽  
Baolin Zhang ◽  
Songbo Xie ◽  
Boning Yang ◽  
Qin Xu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Blood Brain Barrier ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Tween 80 ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Brain Barrier ◽  
Oxide Nanoparticles ◽  
Pass Through

scholarly journals Uptake and transcytosis of functionalized superparamagnetic iron oxide nanoparticles in an in vitro blood brain barrier model

2018 ◽  
Vol 6 (2) ◽  
pp. 314-323 ◽  
Author(s):  
Angela Ivask ◽  
Emily H. Pilkington ◽  
Thomas Blin ◽  
Aleksandr Käkinen ◽  
Heiki Vija ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Blood Brain Barrier ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Brain Barrier ◽  
Oxide Nanoparticles ◽  
Phosphoryl Choline ◽  
Blood Brain

Phosphoryl choline grafting secured high cellular uptake and increased transcytosis of superparamagnetic iron oxide nanoparticles through a model blood brain barrier.

Magnetic targeting with superparamagnetic iron oxide nanoparticles for in vivo glioma

2017 ◽  
Vol 6 (5) ◽  
pp. 449-472 ◽  
Author(s):  
Marina Fontes de Paula Aguiar ◽  
Javier Bustamante Mamani ◽  
Taylla Klei Felix ◽  
Rafael Ferreira dos Reis ◽  
Helio Rodrigues da Silva ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Process Efficiency ◽  
Cochrane Library ◽  
Oxide Nanoparticles ◽  
Magnetic Targeting

AbstractThe purpose of this study was to review the use of the magnetic targeting technique, characterized by magnetic driving compounds based on superparamagnetic iron oxide nanoparticles (SPIONs), as drug delivery for a specific brain locus in gliomas. We reviewed a process mediated by the application of an external static magnetic field for targeting SPIONs in gliomas. A search of PubMed, Cochrane Library, Scopus, and Web of Science databases identified 228 studies, 23 of which were selected based on inclusion criteria and predetermined exclusion criteria. The articles were analyzed by physicochemical characteristics of SPIONs used, cell types used for tumor induction, characteristics of experimental glioma models, magnetic targeting technical parameters, and analysis method of process efficiency. The study shows the highlights and importance of magnetic targeting to optimize the magnetic targeting process as a therapeutic strategy for gliomas. Regardless of the intensity of the patterned magnetic field, the time of application of the field, and nanoparticle used (commercial or synthesized), all studies showed a vast advantage in the use of magnetic targeting, either alone or in combination with other techniques, for optimized glioma therapy. Therefore, this review elucidates the preclinical and therapeutic applications of magnetic targeting in glioma, an innovative nanobiotechnological method.

scholarly journals Examining the effect of ions and proteins on the heat dissipation of iron oxide nanocrystals

RSC Advances ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 1443-1450
Author(s):  
V. Kalidasan ◽  
X. L. Liu ◽  
Y. Li ◽  
P. J. Sugumaran ◽  
A. H. Liu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Heat Dissipation ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Alternating Magnetic Field ◽  
Oxide Nanoparticles

In this paper, the effect and contribution of physiological components like ions and proteins under an applied alternating magnetic field (AMF) towards heat dissipation of superparamagnetic iron oxide nanoparticles (SPIONs) are discussed.

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