Platinum Nanoparticles: Efficient and Stable Catechol Oxidase Mimetics

2015 ◽  
Vol 7 (35) ◽  
pp. 19709-19717 ◽  
Author(s):  
Yi Liu ◽  
Haohao Wu ◽  
Yu Chong ◽  
Wayne G. Wamer ◽  
Qingsu Xia ◽  
...  
Cosmetics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 88
Author(s):  
Shilpi Goenka ◽  
Jimmy Toussaint

Hypopigmentation disorders due to an underproduction of the pigment melanin by melanocytes cause uneven skin coloration, while in hair follicles they cause grey hair. There is a need for novel materials which can stimulate melanogenesis in the skin and hair for personal care use. While titanium dioxide, gold and silver nanoparticles have been extensively used for applications in cosmetic and personal-care products (PCP), the use of relatively inert platinum nanoparticles (PtNPs) has remained underappreciated. PtNPs have been reported to be a mimetic of the enzyme catechol oxidase with small size PtNPs reported to exhibit a higher catechol oxidase activity in a cell-free system, but no testing has been conducted in melanocytes to date. Herein, we have investigated if PtNPs of two sizes (SPtNP: 5 nm; LPtNP: 50 nm) might have an effect on melanogenesis. To this end, we have used MNT-1 human melanoma cells and primary human melanocytes from moderately-pigmented skin (HEMn-MP). Both SPtNP and LPtNP were nontoxic over a concentration range 6.25–25 μg/mL, hence these concentrations were used in further experiments. Both PtNPs stimulated higher extracellular melanin levels than control; SPtNP at concentrations 12.5 and 25 μg/mL significantly stimulated higher levels of extracellular melanin as compared to similar concentrations of LPtNP in MNT-1 cells, in the absence of ROS generation. The effects of PtNPs on melanin secretion were reversible upon removal of PtNPs from the culture medium. The results of primary particle size-specific augmentation of extracellular melanin by SPtNPs were also validated in HEMn-MP cells. Our results thus provide a proof-of-principle that SPtNP might hold potential as a candidate for the treatment of white skin patches, for sunless skin-tanning and for use in anti-greying hair products in cosmetics.


2011 ◽  
Vol 1 (2) ◽  
pp. 162-165 ◽  
Author(s):  
Yoko Yoshihisa ◽  
Mariame Ali Hassan ◽  
Takashi Kondo ◽  
Tadamichi Shimizu

2020 ◽  
Vol 9 (1) ◽  
pp. 386-398 ◽  
Author(s):  
Mahmood S. Jameel ◽  
Azlan Abdul Aziz ◽  
Mohammed Ali Dheyab

AbstractPlatinum nanoparticles (Pt NPs) have attracted interest in catalysis and biomedical applications due to their unique structural, optical, and catalytic properties. However, the conventional synthesis of Pt NPs using the chemical and physical methods is constrained by the use of harmful and costly chemicals, intricate preparation requirement, and high energy utilization. Hence, this review emphasizes on the green synthesis of Pt NPs using plant extracts as an alternative approach due to its simplicity, convenience, inexpensiveness, easy scalability, low energy requirement, environmental friendliness, and minimum usage of hazardous materials and maximized efficiency of the synthesis process. The underlying complex processes that cover the green synthesis (biosynthesis) of Pt NPs were reviewed. This review affirms the effects of different critical parameters (pH, reaction temperature, reaction time, and biomass dosage) on the size and shape of the synthesized Pt NPs. For instance, the average particle size of Pt NPs was reported to decrease with increasing pH, reaction temperature, and concentration of plant extract.


ACS Nano ◽  
2021 ◽  
Vol 15 (2) ◽  
pp. 2643-2653 ◽  
Author(s):  
Jean-François Lemineur ◽  
Paolo Ciocci ◽  
Jean-Marc Noël ◽  
Hongxin Ge ◽  
Catherine Combellas ◽  
...  

2021 ◽  
Vol 46 (13) ◽  
pp. 9215-9221
Author(s):  
Guirong Zhang ◽  
Huihui Zhang ◽  
Lushi Tan ◽  
Zhejuan Zhang ◽  
Jiaxing Lu

2021 ◽  
Vol 4 (4) ◽  
pp. 312-321
Author(s):  
Xiongjie Jin ◽  
Rio Tsukimura ◽  
Takeshi Aihara ◽  
Hiroki Miura ◽  
Tetsuya Shishido ◽  
...  

2021 ◽  
Vol 867 ◽  
pp. 159030
Author(s):  
Yu Hao ◽  
Shaohua Chen ◽  
Luming Wu ◽  
Rui Chen ◽  
Pingchuan Sun ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document