Highly Efficient FRET System Capable of Deep Photodynamic Therapy Established on X-ray Excited Mesoporous LaF3:Tb Scintillating Nanoparticles

2015 ◽  
Vol 7 (22) ◽  
pp. 12261-12269 ◽  
Author(s):  
Yong’an Tang ◽  
Jun Hu ◽  
Ahmed H. Elmenoufy ◽  
Xiangliang Yang
Keyword(s):  
Photodynamic Therapy ◽  
X Ray ◽  
Highly Efficient

scholarly journals X-ray induced photodynamic therapy (PDT) with a mitochondria-targeted liposome delivery system

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Xuefan Gu ◽  
Chao Shen ◽  
Hua Li ◽  
Ewa M. Goldys ◽  
Wei Deng
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
X Ray

scholarly journals X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy

Theranostics ◽  
2016 ◽  
Vol 6 (13) ◽  
pp. 2295-2305 ◽  
Author(s):  
Geoffrey D. Wang ◽  
Ha T. Nguyen ◽  
Hongmin Chen ◽  
Phillip B. Cox ◽  
Lianchun Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
X Ray

Valley density profile for highly efficient x-ray lasers with good beam quality

2007 ◽  
Vol 32 (5) ◽  
pp. 491 ◽  
Author(s):  
J. Zhao ◽  
Q. L. Dong ◽  
J. Zhang
Keyword(s):  
Density Profile ◽  
Beam Quality ◽  
X Ray ◽  
Highly Efficient ◽  
Good Beam Quality

scholarly journals Highly efficient Na_5Gd_9F_32:Tb^3+ glass ceramic as nanocomposite scintillator for X-ray imaging

2017 ◽  
Vol 8 (1) ◽  
pp. 41 ◽  
Author(s):  
WeiPing Chen ◽  
JiangKun Cao ◽  
FangFang Hu ◽  
RongFei Wei ◽  
LiPing Chen ◽  
...  
Keyword(s):  
Glass Ceramic ◽  
X Ray ◽  
Highly Efficient ◽  
X Ray Imaging

Synthesis of Y2O3: Eu Luminescent Phosphor with Increased Dispersion for Use in Medical Purposes

2021 ◽  
Vol 1040 ◽  
pp. 61-67
Author(s):  
Anna B. Vlasenko ◽  
Vadim V. Bakhmetyev ◽  
Sergey V. Mjakin
Keyword(s):  
Particle Size ◽  
Photodynamic Therapy ◽  
Visible Light ◽  
Modern Method ◽  
The Body ◽  
Hydrothermal Processing ◽  
X Ray ◽  
Microwave Annealing ◽  
Body Tissues ◽  
Pyrogenic Silica

Photodynamic therapy (PDT) is a promising modern method for treatment of oncological, bacterial, fungal and viral diseases. However, its application is limited to diseases with superficial localization since the body tissues are not transparent for visible light. To address this problem and extend PDT application to abdominal diseases, an enhanced method of X-ray photodynamic therapy (XRPDT) is suggested, involving X-ray radiation easily penetrating the body tissues. The implementation of this approach requires the development of a pharmacological drug including a photosensitizer stimulated by visible light to yield active oxygen and a nanosized phosphor converting X-ray radiation into visible light with the wavelength required for the photosensitizer activation. This study is aimed at obtaining X-ray stimulated phosphors with nanosized particles suitable for XRPDT application. For this purpose, Y2O3:Eu phosphors were synthesized via hydrothermal processing of the corresponding mixed acetate followed by annealing. To prevent from the undesirable agglomeration of the particles in the course of hydrothermal synthesis and subsequent annealing, different techniques were used, including rapid thermal annealing (RTA), microwave annealing and addition of finely dispersed pyrogenic silica (aerosil) to the phosphor. The microwave annealing was carried out using a special installation including a resonance chamber for maintaining a standing wave of microwave radiation. The performed research allowed the determination of hydrothermal processing optimal duration affording the synthesis of phosphors with the highest luminescence brightness. The application of microwave annealing is found to provide phosphors with a more perfect crystal structure compared with RTA. The developed method of Y2O3:Eu phosphor synthesis involving pyrogenic silica addition to the autoclave allowed the preparation of samples with the amorphous structure and significantly reduced the particle size without a considerable decrease in the luminescence brightness. The particle size of the phosphor synthesized with aerosil addition is less than 100 nm that allows its implementation in pharmacological drugs for XRPDT.

scholarly journals Super Long Green Persistent Luminescence from X-Ray Excited β-NaYF4: Tb3+

2019 ◽  
Author(s):  
Yue Hu ◽  
Yanmin Yang ◽  
Xiaoxiao Li ◽  
Xin Wang ◽  
Yunqian Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Light Source ◽  
Green Emission ◽  
Persistent Luminescence ◽  
Tunneling Model ◽  
X Ray ◽  
Long Afterglow ◽  
Photo Stability ◽  
F Centers

Here, we have discovered a X-ray excited long afterglow phosphor β-NaYF4: Tb3+. After the irradiation of X-ray, the green emission can persist for more than 240 h. After 36 h, the afterglow intensity arrived at 0.69 mcd•m-2, which can clearly be observed by naked eyes. Even after 84 h, the afterglow emission brightness still reached 0.087 mcd•m-2. Also, combined with the results of thermoluminescence and photoluminescence, the super long afterglow emission of β-NaYF4: Tb3+ can be ascribed to the tunneling model associated with F centers. More importantly, the super long green afterglow emission of β-NaYF4: Tb3+ has been successfully used as in vivo light source to activate g-C3N4 for photodynamic therapy（PDT）and bacteria destruction. Furthermore, super long persistent luminescence of β-NaYF4: Tb3+ could be repeatedly charged by X-ray for many circulations, which indicates that the phosphors have high photo stability under repeated cycles of alternating X-ray irradiation.

Verteprofin conjugated to gold nanoparticles for fluorescent cellular bioimaging and X-ray mediated photodynamic therapy

2017 ◽  
Vol 184 (6) ◽  
pp. 1765-1771 ◽  
Author(s):  
Sandhya Clement ◽  
Wenjie Chen ◽  
Ayad G. Anwer ◽  
Ewa M. Goldys
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
X Ray
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