Application of a Reactive Oxygen Species-Responsive Drug-Eluting Coating for Surface Modification of Vascular Stents

2021 ◽  
Author(s):  
Kebing Wang ◽  
Tengda Shang ◽  
Lu Zhang ◽  
Lei Zhou ◽  
Changqi Liu ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Surface Modification ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Vascular Stents ◽  
Drug Eluting

Effect of reactive oxygen species generated with ultraviolet lamp and plasma on polyimide surface modification

2017 ◽  
Vol 49 (11) ◽  
pp. 1069-1077 ◽  
Author(s):  
Takahiro Kondo ◽  
Ryota Watanabe ◽  
Yuta Shimoyama ◽  
Kazuho Shinohe ◽  
Sergei A. Kulinich ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Surface Modification ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Ultraviolet Lamp

scholarly journals Development of superoxide dismutase mimetic surfaces to reduce accumulation of reactive oxygen species for neural interfacing applications

2014 ◽  
Vol 2 (16) ◽  
pp. 2248-2258 ◽  
Author(s):  
Kelsey A. Potter-Baker ◽  
Jessica K. Nguyen ◽  
Kyle M. Kovach ◽  
Martin M. Gitomer ◽  
Tyler W. Srail ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Superoxide Dismutase ◽  
Surface Modification ◽  
Composite Coating ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Reactive Oxygen Species Accumulation ◽  
Species Accumulation ◽  
Neural Interfacing

In order to reduce inflammatory-mediated reactive oxygen species accumulation, we have developed an anti-oxidative surface modification consisting of a composite coating of adsorbed and immobilized superoxide dismutase mimetic.

scholarly journals Surface modification of polyethylene microplastic particles during the aqueous-phase ozonation process

2020 ◽  
Vol 26 (5) ◽  
pp. 200412-0
Author(s):  
Rabia Zafar ◽  
Seon Yeong Park ◽  
Chang Gyun Kim
Keyword(s):  
Reactive Oxygen Species ◽  
Surface Modification ◽  
Reaction Time ◽  
Aqueous Phase ◽  
Natural Waters ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Ftir Analysis ◽  
Ozone Uptake ◽  
Ozonation Process

Microplastics coexist with the chemical reactive oxygen species in natural waters, however, there is still a lack to elucidate the effect of these radicals on the microplastic surficial oxidation. In this study, the ozonation of polyethylene microplastics was carried out under varying ozone dosages ranging from 4 to 7 mg/min for 60, 120 and 180 min, where its ozone uptake was iodometrically compared and surficial modification was spectroscopically analyzed using FTIR and XPS. For that, the lowest ozone uptake was 16% at 4 mg/min ozone supplied for 60 min whereas the highest was observed of 44% at 7 mg/min ozone added for 180 min. Moreover, in the FTIR analysis, carbonyl (1,600-1,800 cm<sup>-1</sup>) and hydroxyl (3,200-3,600 cm<sup>-1</sup>) indices were improved more than 20% and 13% when they were ozonized at 7 mg/min for 180 min compared to 4 mg/min for 60 min, respectively. XPS also revealed that 7 mg/min of ozone supplied for 180 min provided the highest of oxygen functionalities, but while there was no significant change in C-C bond. It can be concluded that the surficial modification of PE including formation of oxygen functionalities could be more preferably influenced by the reaction time than ozone dosages.

Mitochondria as a source of reactive oxygen species

2009 ◽  
pp. c3 ◽  
Author(s):  
Helena M. Cochemé ◽  
Michael P. Murphy
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Oxygen Species

Clinical aspects of reactive oxygen and nitrogen species

2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Risk Factor ◽  
Endothelial Dysfunction ◽  
Vascular Tissue ◽  
Rapid Development ◽  
Reactive Oxygen ◽  
Clinical Aspects ◽  
No Production ◽  
Oxygen Species

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.

Fas ligand expression in rat kupffer cells in response to lipopolysaccharide is mediated by reactive oxygen species

2001 ◽  
Vol 120 (5) ◽  
pp. A361-A361
Author(s):  
K UCHIKURA ◽  
T WADA ◽  
Z SUN ◽  
S HOSHINO ◽  
G BULKLEY ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Kupffer Cells ◽  
Fas Ligand ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Ligand Expression
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