scholarly journals Flexible Materials for High-Resolution 3D Printing of Microfluidic Devices with Integrated Droplet Size Regulation

2021 ◽  
Author(s):  
Niclas Weigel ◽  
Max J. Männel ◽  
Julian Thiele
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Droplet Size ◽  
Microfluidic Devices ◽  
Size Regulation ◽  
Flexible Materials

Understanding and improving FDM 3D printing to fabricate high-resolution and optically transparent microfluidic devices

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Reverson Fernandes Quero ◽  
Gessica Domingos Silveira ◽  
Jose Alberto Fracassi da Silva ◽  
Dosil Pereira de Jesus
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
Fused Deposition ◽  
Optically Transparent ◽  
Deposition Modeling

The fabrication of microfluidic devices through Fused Deposition Modeling (FDM) 3D printing has faced several challenges, mainly regarding obtaining microchannels with suitable transparency and sizes. Thus, the use of this...

scholarly journals Rapid and Inexpensive Fabrication of Multi-Depth Microfluidic Device using High-Resolution LCD Stereolithographic 3D Printing

2019 ◽  
Vol 3 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Mohamed ◽  
Hitendra Kumar ◽  
Zongjie Wang ◽  
Nicholas Martin ◽  
Barry Mills ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Soft Lithography ◽  
Liquid Crystal Display ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Single Step ◽  
Droplet Generator ◽  
Rapid Fabrication ◽  
Printing System

With the dramatic increment of complexity, more microfluidic devices require 3D structures, such as multi-depth and -layer channels. The traditional multi-step photolithography is time-consuming and labor-intensive and also requires precise alignment during the fabrication of microfluidic devices. Here, we present an inexpensive, single-step, and rapid fabrication method for multi-depth microfluidic devices using a high-resolution liquid crystal display (LCD) stereolithographic (SLA) three-dimensional (3D) printing system. With the pixel size down to 47.25 μm, the feature resolutions in the horizontal and vertical directions are 150 μm and 50 μm, respectively. The multi-depth molds were successfully printed at the same time and the multi-depth features were transferred properly to the polydimethylsiloxane (PDMS) having multi-depth channels via soft lithography. A flow-focusing droplet generator with a multi-depth channel was fabricated using the presented 3D printing method. Experimental results show that the multi-depth channel could manipulate the morphology and size of droplets, which is desired for many engineering applications. Taken together, LCD SLA 3D printing is an excellent alternative method to the multi-step photolithography for the fabrication of multi-depth microfluidic devices. Taking the advantages of its controllability, cost-effectiveness, and acceptable resolution, LCD SLA 3D printing can have a great potential to fabricate 3D microfluidic devices.

scholarly journals Cheap, Versatile, and Turnkey Fabrication of Microfluidic Master Molds Using Consumer Grade LCD Stereolithography 3D Printing

2021 ◽  
Author(s):  
Vincent G. Colin ◽  
Théo A. Travers ◽  
Denis Gindre ◽  
Régis Barillé ◽  
Matthieu Loumaigne
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Cost Efficiency ◽  
Soft Lithography ◽  
Microfluidic Devices ◽  
Teaching Tool ◽  
3D Printer ◽  
Uv Led ◽  
Led Array ◽  
3D Printers

Abstract The recent development of 3D printers allowed a lot of limitations in the field of microfabrication to be circumvented. The ever-growing chase for smaller dimensions has come to an end in domains such as microfluidics, and the focus now shifted to a cost-efficiency challenge. In this paper, the use of a high-resolution stereolithography LCD 3D printer is investigated for fast and cheap production of microfluidic master molds. More precisely, we use the UV LED array and the LCD matrix of the printer as an illuminator and a programmable photomask for soft lithography. The achieved resolution of around 100µm is mainly limited by the pixel geometry of the LCD matrix. A tree-shape gradient mixer was fabricated using the presented method. It shows very good performances despite the presence of sidewall ripples due to the uneven pixel geometry of the LCD matrix. Given its sub-€1,000 cost, this method is a very good entry point for labs wishing to explore the potential of microfluidic devices in their experiments, as well as a teaching tool for introducing students to microfluidics.

scholarly journals Spatially and optically tailored 3D printing for highly miniaturized and integrated microfluidics

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jose L. Sanchez Noriega ◽  
Nicholas A. Chartrand ◽  
Jonard Corpuz Valdoz ◽  
Collin G. Cribbs ◽  
Dallin A. Jacobs ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Microfluidic Devices ◽  
Device Fabrication ◽  
Material Strength ◽  
3D Printer ◽  
Digital Light Processing ◽  
Spatially Distributed ◽  
Integrated Microfluidics ◽  
High Degree

AbstractTraditional 3D printing based on Digital Light Processing Stereolithography (DLP-SL) is unnecessarily limiting as applied to microfluidic device fabrication, especially for high-resolution features. This limitation is due primarily to inherent tradeoffs between layer thickness, exposure time, material strength, and optical penetration that can be impossible to satisfy for microfluidic features. We introduce a generalized 3D printing process that significantly expands the accessible spatially distributed optical dose parameter space to enable the fabrication of much higher resolution 3D components without increasing the resolution of the 3D printer. Here we demonstrate component miniaturization in conjunction with a high degree of integration, including 15 μm × 15 μm valves and a 2.2 mm × 1.1 mm 10-stage 2-fold serial diluter. These results illustrate our approach’s promise to enable highly functional and compact microfluidic devices for a wide variety of biomolecular applications.

scholarly journals A Review of Current Methods in Microfluidic Device Fabrication and Future Commercialization Prospects

Inventions ◽  
2018 ◽  
Vol 3 (3) ◽  
pp. 60 ◽  
Author(s):  
Bruce Gale ◽  
Alexander Jafek ◽  
Christopher Lambert ◽  
Brady Goenner ◽  
Hossein Moghimifam ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Microfluidic Device ◽  
Microfluidic Devices ◽  
Device Fabrication ◽  
Costs And Benefits ◽  
Engineering Applications ◽  
Commercial Use ◽  
Microfabrication Techniques

Microfluidic devices currently play an important role in many biological, chemical, and engineering applications, and there are many ways to fabricate the necessary channel and feature dimensions. In this review, we provide an overview of microfabrication techniques that are relevant to both research and commercial use. A special emphasis on both the most practical and the recently developed methods for microfluidic device fabrication is applied, and it leads us to specifically address laminate, molding, 3D printing, and high resolution nanofabrication techniques. The methods are compared for their relative costs and benefits, with special attention paid to the commercialization prospects of the various technologies.

High-resolution 3D printing in seconds

Nature ◽  
2020 ◽  
Vol 588 (7839) ◽  
pp. 594-595
Author(s):  
Cameron Darkes-Burkey ◽  
Robert F. Shepherd
Keyword(s):  
High Resolution ◽  
3D Printing

Process development for high-resolution 3D-printing of bioresorbable vascular stents

2017 ◽  
Author(s):  
Henry Oliver T. Ware ◽  
Adam C. Farsheed ◽  
Robert van Lith ◽  
Evan Baker ◽  
Guillermo Ameer ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Process Development ◽  
Vascular Stents

Simplified fabrication of integrated microfluidic devices using fused deposition modeling 3D printing

2017 ◽  
Vol 242 ◽  
pp. 35-40 ◽  
Author(s):  
Gabriel Gaal ◽  
Melissa Mendes ◽  
Tiago P. de Almeida ◽  
Maria H.O. Piazzetta ◽  
Ângelo L. Gobbi ◽  
...  
Keyword(s):  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
Fused Deposition ◽  
Deposition Modeling

scholarly journals Dual Sacrificial Molding: Fabricating 3D Microchannels with Overhang and Helical Features

Micromachines ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 523 ◽  
Author(s):  
Wei Goh ◽  
Michinao Hashimoto
Keyword(s):  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
High Impact ◽  
3D Printer ◽  
Original Design ◽  
Fused Deposition ◽  
Deposition Modeling ◽  
Indispensable Tool ◽  
Single Material

Fused deposition modeling (FDM) has become an indispensable tool for 3D printing of molds used for sacrificial molding to fabricate microfluidic devices. The freedom of design of a mold is, however, restricted to the capabilities of the 3D printer and associated materials. Although FDM has been used to create a sacrificial mold made with polyvinyl alcohol (PVA) to produce 3D microchannels, microchannels with free-hanging geometries are still difficult to achieve. Herein, dual sacrificial molding was devised to fabricate microchannels with overhang or helical features in PDMS using two complementary materials. The method uses an FDM 3D printer equipped with two extruders and filaments made of high- impact polystyrene (HIPS) and PVA. HIPS was initially removed in limonene to reveal the PVA mold harboring the design of microchannels. The PVA mold was embedded in PDMS and subsequently removed in water to create microchannels with 3D geometries such as dual helices and multilayer pyramidal networks. The complementary pairing of the HIPS and PVA filaments during printing facilitated the support of suspended features of the PVA mold. The PVA mold was robust and retained the original design after the exposure to limonene. The resilience of the technique demonstrated here allows us to create microchannels with geometries not attainable with sacrificial molding with a mold printed with a single material.

Highly stretchable hydrogels for UV curing based high-resolution multimaterial 3D printing

2018 ◽  
Vol 6 (20) ◽  
pp. 3246-3253 ◽  
Author(s):  
Biao Zhang ◽  
Shiya Li ◽  
Hardik Hingorani ◽  
Ahmad Serjouei ◽  
Liraz Larush ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Uv Curing ◽  
Digital Light Processing ◽  
Highly Stretchable ◽  
Hydrogel System

We report a highly stretchable hydrogel system that is suitable for digital light processing (DLP) based high-resolution multimaterial 3D printing.

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