Magnetic Nanostructure-Loaded Bicontinuous Nanospheres Support Multicargo Intracellular Delivery and Oxidation-Responsive Morphological Transitions

2020 ◽  
Vol 12 (50) ◽  
pp. 55584-55595
Author(s):  
Mallika Modak ◽  
Sharan Bobbala ◽  
Chamille Lescott ◽  
Yu-Gang Liu ◽  
Vikas Nandwana ◽  
...  
Keyword(s):  
Intracellular Delivery ◽  
Magnetic Nanostructure ◽  
Morphological Transitions

Probing Cellular Outcomes Using Heterobivalent Constructs

2019 ◽  
Author(s):  
Rohit Bhadoria ◽  
Kefeng Ping ◽  
Christer Lohk ◽  
Ivar Järving ◽  
Pavel Starkov
Keyword(s):  
Cell Viability ◽  
Small Molecules ◽  
Cellular Uptake ◽  
Kinase Inhibitors ◽  
Rho Kinase ◽  
Intracellular Delivery ◽  
Rho Kinase Inhibitors

<div> <div> <div> <p>Conjugation techniques are central to improving intracellular delivery of bioactive small molecules. However, tracking and assessing the overall biological outcome of these constructs remains poorly understood. We addressed this issue by having developed a focused library of heterobivalent constructs based on Rho kinase inhibitors to probe various scenarios. By comparing induction of a phenotype of interest vs. cell viability vs. cellular uptake, we demonstrate that such conjugates indeed lead to divergent cellular outcomes. </p> </div> </div> </div>

Intracellular Delivery of Nanocarriers for Cancer Therapy

2007 ◽  
Vol 3 (4) ◽  
pp. 329-338 ◽  
Author(s):  
Yah-el Har-el ◽  
Yoshinori Kato
Keyword(s):  
Cancer Therapy ◽  
Intracellular Delivery

DNA Dendrons as Agents for Intracellular Delivery

2021 ◽  
Author(s):  
Max E. Distler ◽  
Michelle H. Teplensky ◽  
Katherine E. Bujold ◽  
Caroline D. Kusmierz ◽  
Michael Evangelopoulos ◽  
...  
Keyword(s):  
Intracellular Delivery

A Comprehensive Review on Intracellular Delivery

2021 ◽  
pp. 2005363
Author(s):  
Dorsa Morshedi Rad ◽  
Maryam Alsadat Rad ◽  
Sajad Razavi Bazaz ◽  
Navid Kashaninejad ◽  
Dayong Jin ◽  
...  
Keyword(s):  
Intracellular Delivery ◽  
Comprehensive Review
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