Bacterial Vesicle-Cancer Cell Hybrid Membrane-Coated Nanoparticles for Tumor Specific Immune Activation and Photothermal Therapy

2020 ◽  
Vol 12 (37) ◽  
pp. 41138-41147
Author(s):  
Dongdong Wang ◽  
Conghui Liu ◽  
Shiquan You ◽  
Kai Zhang ◽  
Meng Li ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Immune Activation ◽  
Cell Hybrid ◽  
Photothermal Therapy ◽  
Hybrid Membrane ◽  
Coated Nanoparticles

scholarly journals Biomimetic Upconversion Nanoparticles and Gold Nanoparticles for Novel Simultaneous Dual-Modal Imaging-Guided Photothermal Therapy of Cancer

Cancers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3136 ◽  
Author(s):  
Ruliang Wang ◽  
Han Yang ◽  
Rongxin Fu ◽  
Ya Su ◽  
Xue Lin ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Photothermal Therapy ◽  
Tumor Targeting ◽  
Imaging System ◽  
Imaging Systems ◽  
Coated Nanoparticles ◽  
Cancer Theranostics

Multimodal imaging-guided near-infrared (NIR) photothermal therapy (PTT) is an interesting and promising cancer theranostic method. However, most of the multimodal imaging systems provide structural and functional information used for imaging guidance separately by directly combining independent imaging systems with different detectors, and many problems arise when trying to fuse different modal images that are serially taken by inviting extra markers or image fusion algorithms. Further, most imaging and therapeutic agents passively target tumors through the enhanced permeability and retention (EPR) effect, which leads to low utilization efficiency. To address these problems and systematically improve the performance of the imaging-guided PTT methodology, we report a novel simultaneous dual-modal imaging system combined with cancer cell membrane-coated nanoparticles as a platform for PTT-based cancer theranostics. A novel detector with the ability to detect both high-energy X-ray and low-energy visible light at the same time, as well as a dual-modal imaging system based on the detector, was developed for simultaneous dual-modal imaging. Cancer cell membrane-coated upconversion nanoparticles (CC-UCNPs) and gold nanoparticles (CC-AuNPs) with the capacity for immune evasion and active tumor targeting were engineered for highly specific imaging and high-efficiency PTT therapy. In vitro and in vivo evaluation of macrophage escape and active homologous tumor targeting were performed. Cancer cell membrane-coated nanoparticles (CC-NPs) displayed excellent immune evasion ability, longer blood circulation time, and higher tumor targeting specificity compared to normal PEGylated nanoparticles, which led to highly specific upconversion luminescence (UCL) imaging and PTT-based anti-tumor efficacy. The anti-cancer efficacy of the dual-modal imaging-guided PTT was also evaluated both in vitro and in vivo. Dual-modal imaging yielded precise anatomical and functional information for the PTT process, and complete tumor ablation was achieved with CC-AuNPs. Our biomimetic UCNP/AuNP and novel simultaneous dual-modal imaging combination could be a promising platform and methodology for cancer theranostics.

Multifunctional magnetic-hollow gold nanospheres for bimodal cancer cell imaging and photothermal therapy

2015 ◽  
Vol 26 (31) ◽  
pp. 315701 ◽  
Author(s):  
Ling-Yu Bai ◽  
Xiao-Quan Yang ◽  
Jie An ◽  
Lin Zhang ◽  
Kai Zhao ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Photothermal Therapy ◽  
Cell Imaging ◽  
Gold Nanospheres ◽  
Cancer Cell Imaging ◽  
Hollow Gold Nanospheres

Erythrocyte membrane nano-capsules: biomimetic delivery and controlled release of photothermal–photochemical coupling agents for cancer cell therapy

2020 ◽  
Vol 49 (8) ◽  
pp. 2645-2651 ◽  
Author(s):  
Shihao Li ◽  
Lin Zhang
Keyword(s):  
Controlled Release ◽  
Cell Therapy ◽  
Blood Cell ◽  
Erythrocyte Membrane ◽  
Cancer Cell ◽  
Red Blood Cell ◽  
Photothermal Therapy ◽  
Cell Membranes ◽  
Coupling Agents ◽  
Red Blood Cell Membranes

A biomimetic nanoreactor Au/TiO2@RBC was fabricated for photothermal therapy by co-encapsulating photothermal agents and photocatalysts in red blood cell membranes.

Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk–Shell Structure Augment Cancer Chemotherapy

Nano Letters ◽  
2019 ◽  
Vol 20 (2) ◽  
pp. 936-946 ◽  
Author(s):  
Di Nie ◽  
Zhuo Dai ◽  
Jialin Li ◽  
Yiwei Yang ◽  
Ziyue Xi ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Cancer Chemotherapy ◽  
Shell Structure ◽  
Coated Nanoparticles

Delicately Designed Cancer Cell Membrane-Camouflaged Nanoparticles for Targeted 19F MR/PA/FL Imaging-Guided Photothermal Therapy

2020 ◽  
Vol 12 (51) ◽  
pp. 57290-57301
Author(s):  
Sha Li ◽  
Weiping Jiang ◽  
Yaping Yuan ◽  
Meiju Sui ◽  
Yuqi Yang ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Photothermal Therapy

scholarly journals Luminescent CaTiO3:Yb,Er nanofibers co-conjugated with Rose Bengal and gold nanorods for potential synergistic photodynamic/photothermal therapy

2017 ◽  
Vol 5 (26) ◽  
pp. 5128-5136 ◽  
Author(s):  
Yike Fu ◽  
Heng Liu ◽  
Zhaohui Ren ◽  
Xiang Li ◽  
Jie Huang ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Gold Nanorods ◽  
Rose Bengal ◽  
Photothermal Therapy ◽  
Cell Killing ◽  
Killing Effect ◽  
Photothermal Phenomenon ◽  
Cell Killing Effect

CaTiO3:Yb,Er nanofibers, co-conjugated with Rose Bengal and gold nanorods, enable a synergistic photodynamic/photothermal phenomenon for superior cancer cell killing effect.

Platelet membrane-coated nanoparticles for targeted drug delivery and local chemo-photothermal therapy of orthotopic hepatocellular carcinoma

2020 ◽  
Vol 8 (21) ◽  
pp. 4648-4659 ◽  
Author(s):  
Long Wu ◽  
Wei Xie ◽  
Hui-Ming Zan ◽  
Zhongzhong Liu ◽  
Ganggang Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Platelet Membrane ◽  
Coated Nanoparticles ◽  
Controllable Release ◽  
Targeted Drug

Specific targeted drug delivery and controllable release of drugs at tumor regions are two of the main challenges for hepatocellular carcinoma (HCC) therapy, particularly post metastasis.

scholarly journals Photothermal Therapy: Endosomal Confinement of Gold Nanospheres, Nanorods, and Nanoraspberries Governs Their Photothermal Identity and Is Beneficial for Cancer Cell Therapy (Adv. Biosys. 4/2020)

2020 ◽  
Vol 4 (4) ◽  
pp. 2070042 ◽  
Author(s):  
Anouchka Plan Sangnier ◽  
Aurore Van de Walle ◽  
Romain Aufaure ◽  
Magali Fradet ◽  
Laurence Motte ◽  
...  
Keyword(s):  
Cell Therapy ◽  
Cancer Cell ◽  
Photothermal Therapy ◽  
Gold Nanospheres

Docetaxel-loaded SiO2@Au@GO core–shell nanoparticles for chemo-photothermal therapy of cancer cells

RSC Advances ◽  
2016 ◽  
Vol 6 (54) ◽  
pp. 48379-48386 ◽  
Author(s):  
Xiaolin Li ◽  
Zhi Yang ◽  
Nantao Hu ◽  
Liying Zhang ◽  
Yafei Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Photothermal Therapy ◽  
Prostate Cancer Cell ◽  
Core Shell ◽  
Human Prostate Cancer ◽  
Human Prostate Cancer Cell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

The multifunctional antitumor SiO2@Au@GO core–shell nanoparticles (NPs) have been fabricated for serving as drug nanocarrier and photothermal inducer to have a treatment on human prostate cancer cell DU 145.

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