Preparation, Characterization, and Release Behavior of Doxorubicin hydrochloride from Dual Cross-Linked Chitosan/Alginate Hydrogel Beads

2020 ◽  
Vol 3 (5) ◽  
pp. 3057-3065 ◽  
Author(s):  
Ting Wu ◽  
Shaobin Yu ◽  
Dongzi Lin ◽  
Zhimin Wu ◽  
Jun Xu ◽  
...  
RSC Advances ◽  
2019 ◽  
Vol 9 (48) ◽  
pp. 27961-27972
Author(s):  
Dan Zheng ◽  
Bo Bai ◽  
Xiaohui Xu ◽  
Yunhua He ◽  
Shan Li ◽  
...  

Composite hydrogel beads prepared by sodium alginate with hydrophilicity and detonation nanodiamond with photothermal conversion property exhibited apparent water release behavior under illumination.


2019 ◽  
Vol 134 ◽  
pp. 210-215 ◽  
Author(s):  
Wei Xu ◽  
Lu Huang ◽  
Weiping Jin ◽  
Peipei Ge ◽  
Bakht Ramin Shah ◽  
...  

2017 ◽  
Vol 105 ◽  
pp. 924-930 ◽  
Author(s):  
Yang Li ◽  
Chao Feng ◽  
Jing Li ◽  
Yuzhi Mu ◽  
Ya Liu ◽  
...  

2021 ◽  
Author(s):  
Xiao Zhang ◽  
Zhiyue Li ◽  
Taoyi Zhang ◽  
Jing Chen ◽  
Wenxi Ji ◽  
...  

A novel zeolitic imidazolate framework-8 (ZIF-8) alginate composite hydrogel material (PVA/SA@ZIF-8) is alginate composite bead which was fabricated by grafting ZIF-8 on the surface of the sodium alginate hydrogel beads...


2021 ◽  
Vol 889 ◽  
pp. 91-97
Author(s):  
Suntree Sangjan ◽  
Wadchara Thongsamer

A novel slow-release N-fertilizer hydrogel beads were developed using sodium alginate (SA) and alginate-talcum (ST) composite as N-absorbent. In this work, the hydrogel composite were fabricated by simple method and low cost. N-fertilizer hydrogel beads were prepared two types, for SA types, which were different sodium alginate (1(SA1), 3(SA3), 5(SA5), 7(SA7), and 10(SA10) wt%). And, for ST types, sodium alginate and talcum were vary ratios to 1:0.5(S1T0.5), 1:1(S1T1), and 1:2 (S1T2). The chemical structure of hydrogel composite beads were characterized via Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). The release behavior were investigate by Zero-order kinetic model, First-order kinetic model, Higuchi model and Korsmeyer-Peppas model. We have found that the N-fertilizer release constants in Korsmeyer-Peppas model were decrease with increase SA content for 1-5 wt% in SA hydrogel beads. However, SA contents were more than 5 wt% which rapidly enhanced fertilizer release. In addition, to add talcum in ST hydrogel beads significantly reduced fertilizer release rate. The N-fertilizer hydrogel beads exhibits significantly slow release behavior. These results indicates that the development of slow-release fertilizer hydrogel beads can be improve the effectiveness of N-fertilizer.


e-Polymers ◽  
2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Piotr Woźniak ◽  
Marek Kozicki ◽  
Janusz M. Rosiak ◽  
Jacek Przybylski ◽  
Malgorzata Lewandowska-Szumieł

AbstractHuman cartilage derived cells were encapsulated in alginate hydrogel beads. Viability of the cells was determined using both qualitative (microscopy) and quantitative (MTT and NR assays) examination. Microscopy indicated that encapsulated cells remained viable during the 7-days experiment. The quantitative tests failed to give reliable results. Possible factors affecting the results of the quantitative study are discussed.


Author(s):  
MIZANURFAKHRI GHAZALI ◽  
SHARANIZA AB-RAHIM ◽  
MUDIANA MUHAMAD

Introduction: Human Norovirus (HuNoV), a food-borne virus is the leading cause for acute gastroenteritis. However, its inability to propagate in vitropersists as major challenge in understanding HuNoV biology.Objective: This study aims to determine an effective culture system for HuNoV.Methods: The Caco-2 cells were cocultured with Raji B cells on alginate hydrogel beads. Scanning electron microscopy (SEM) was performed to confirmthe three-dimensional (3D) cells morphology. Western blot (WB) analysis was performed to detect protein markers expressed by Microfold (M) cells.Results: Optimization of Caco-2 cells monoculture in the alginate hydrogel beads showed optimum number of cells of 1 × 106 cells/ml, indicatedby the intact structure of the beads. Result of SEM showed clear structure of monoculture in the alginate hydrogel beads indicated by the presenceof smooth and regular apical surface while the coculture showed reduced apical surface of M cells. The result of WB showed downregulation ofUlex europaeus antibody expression.Conclusion: It is evident that the expression of M cells grown in 3D alginate hydrogel beads was successful, indicated by the structural morphologyseen under SEM as well as expression of protein marker by M cells. This established in vitro system is highly potential for cultivation of HuNoV.


2019 ◽  
Vol 7 (3) ◽  
pp. 103134 ◽  
Author(s):  
Sudeshna Saha ◽  
Manisha Venkatesh ◽  
Hirakendu Basu ◽  
Mehzabin Vivek Pimple ◽  
Rakesh Kumar Singhal

2015 ◽  
Vol 3 (43) ◽  
pp. 21690-21698 ◽  
Author(s):  
Dong-En Wang ◽  
Yaolei Wang ◽  
Chang Tian ◽  
Longlong Zhang ◽  
Xiang Han ◽  
...  

A new polydiacetylene liposome-based sensor was successfully constructed for the colorimetric and fluorometric detection of Pb2+.


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