scholarly journals Radiofrequency and Near-Infrared Responsive Core–Shell Nanostructures Using Layersome Templates for Cancer Treatment

2019 ◽  
Vol 3 (1) ◽  
pp. 273-281 ◽  
Author(s):  
Animesh Pan ◽  
Md Golam Jakaria ◽  
Samantha A. Meenach ◽  
Geoffrey D. Bothun
Micromachines ◽  
2018 ◽  
Vol 9 (8) ◽  
pp. 400 ◽  
Author(s):  
Kumbam Lingeshwar Reddy ◽  
Neeraj Prabhakar ◽  
Jessica Rosenholm ◽  
Venkata Krishnan

Optical imaging of cancer cells using near infrared (NIR) light is currently an active area of research, as this spectral region directly corresponds to the therapeutic window of biological tissues. Upconversion nanocrystals are photostable alternatives to conventional fluorophores. In our work, we have prepared upconversion nanocrystals of NaYF4:Yb/Er and encapsulated them in silica to form core-shell structures. The as-prepared core-shell nanostructures have been characterized for their structure, morphology, and optical properties using X-ray diffraction, transmission electron microscopy coupled with elemental mapping, and upconversion luminescence spectroscopy, respectively. The cytotoxicity examined using cell viability assay indicated a low level of toxicity of these core-shell nanostructures. Finally, these core-shell nanostructures have been utilized as photostable probes for NIR light enabled optical imaging of human breast cancer cells. This work paves the way for the development of advanced photostable, biocompatible, low-toxic core-shell nanostructures for potential optical imaging of biological cells and tissues.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Wan-Ni Wang ◽  
Wang Dong ◽  
Chen-Xi Huang ◽  
Bo Liu ◽  
Sheng Cheng ◽  
...  

Constructing near-infrared-light-mediated core-shell nanostructures incorporating upconversion nanoparticles (UCNPs) and semiconductors is of great importance for potential applications in photocatalysis, nano-biomedical engineering, solar cell, etc. In this work, we have demonstrated a two-step solution process to synthesize [email protected] core-shell nanoparticles (CSN). Firstly, a layer of AA-Zn(Cd)[OH]4− composites was coated on UCNPs to form UCNPs@AA-Zn(Cd)[OH]4− composites, which has been converted to [email protected] CSN via sulfidation reaction process using thioacetamide (TAA) as the sulfur source. Moreover, the [email protected] yolk-shell nanoparticles (YSN) have been obtained from the [email protected] CSN after calcination at 400°C, which show significantly photocatalytic activity for reduction of Cr(VI) under near-infrared light. All these can be attributed to the enhanced crystallization degree, resulting in enhanced energy transfer efficiency and separation efficiency of the photogenerated electrons and holes. An alternative strategy is provided in this study for fabrication of UCNP/semiconductor composites for various applications.


2019 ◽  
Vol 2 (3) ◽  
pp. 1516-1524 ◽  
Author(s):  
Jing Pan ◽  
Lingling Zhang ◽  
Songtao Zhang ◽  
Zhan Shi ◽  
Xiao Wang ◽  
...  

2017 ◽  
Vol 724 ◽  
pp. 481-491 ◽  
Author(s):  
Ramachandran Balaji ◽  
Suneel Kumar ◽  
Kumbam Lingeshwar Reddy ◽  
Vipul Sharma ◽  
Kaustava Bhattacharyya ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Liang Chen ◽  
Wenxing Wang ◽  
Jia Tian ◽  
Fanxing Bu ◽  
Tiancong Zhao ◽  
...  

AbstractThe potential applications of covalent organic frameworks (COFs) can be further developed by encapsulating functional nanoparticles within the frameworks. However, the synthesis of monodispersed core@shell structured COF nanocomposites without agglomeration remains a significant challenge. Herein, we present a versatile dual-ligand assistant strategy for interfacial growth of COFs on the functional nanoparticles with abundant physicochemical properties. Regardless of the composition, geometry or surface properties of the core, the obtained core@shell structured nanocomposites with controllable shell-thickness are very uniform without agglomeration. The derived bowl-shape, yolk@shell, core@satellites@shell nanostructures can also be fabricated delicately. As a promising type of photosensitizer for photodynamic therapy (PDT), the porphyrin-based COFs were grown onto upconversion nanoparticles (UCNPs). With the assistance of the near-infrared (NIR) to visible optical property of UCNPs core and the intrinsic porosity of COF shell, the core@shell nanocomposites can be applied as a nanoplatform for NIR-activated PDT with deep tissue penetration and chemotherapeutic drug delivery.


2017 ◽  
Vol 46 (36) ◽  
pp. 12147-12157 ◽  
Author(s):  
Chen Wang ◽  
Liangge Xu ◽  
Jiating Xu ◽  
Dan Yang ◽  
Bin Liu ◽  
...  

Core–shell nanostructures consisting of plasmonic materials and lanthanide-doped upconversion nanoparticles (UCNPs) show promising applications in theranostics including bio-imaging, diagnosis and therapy.


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