Pepsin Assisted Doxorubicin Delivery from Mesoporous Silica Nanoparticles Downsizes Solid Tumor Volume and Enhances Therapeutic Efficacy in Experimental Murine Lymphoma

2018 ◽  
Vol 1 (6) ◽  
pp. 2133-2140 ◽  
Author(s):  
Prateek Srivastava ◽  
Sumit Kumar Hira ◽  
Uttam Gupta ◽  
Vivek Kumar Singh ◽  
Ranjeet Singh ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Solid Tumor ◽  
Therapeutic Efficacy ◽  
Tumor Volume ◽  
Mesoporous Silica Nanoparticles ◽  
Murine Lymphoma ◽  
Doxorubicin Delivery

Cisplatin and doxorubicin dual-loaded mesoporous silica nanoparticles for controlled drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (96) ◽  
pp. 94160-94169 ◽  
Author(s):  
Hanwen Li ◽  
Huijuan Yu ◽  
Caiying Zhu ◽  
Jianhua Hu ◽  
Ming Du ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Synergistic Effect ◽  
Silica Nanoparticles ◽  
Therapeutic Efficacy ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery

Multicomponent therapeutic platforms have been proposed to minimize dosage of each drug and reduce toxicity, leading to achieving a synergistic effect and maximizing therapeutic efficacy.

Gold-capped mesoporous silica nanoparticles as an excellent enzyme-responsive nanocarrier for controlled doxorubicin delivery

2019 ◽  
Vol 27 (10) ◽  
pp. 1084-1093 ◽  
Author(s):  
Parvaneh Eskandari ◽  
Bahare Bigdeli ◽  
Mohammad Porgham Daryasari ◽  
Hadi Baharifar ◽  
Behroz Bazri ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Doxorubicin Delivery

Aminated hollow mesoporous silica nanoparticles as an enhanced loading and sustained releasing carrier for doxorubicin delivery

2020 ◽  
Vol 309 ◽  
pp. 110543
Author(s):  
Thi Ngoc Tram Nguyen ◽  
Ngoc Thuy Trang Le ◽  
Ngoc Hoi Nguyen ◽  
Bui Thi Kim Ly ◽  
Trinh Duy Nguyen ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Doxorubicin Delivery ◽  
Hollow Mesoporous Silica

Synthesis of mesoporous silica nanoparticles and nanorods: Application to doxorubicin delivery

2017 ◽  
Vol 68 ◽  
pp. 25-31 ◽  
Author(s):  
Saher Rahmani ◽  
Jean-Olivier Durand ◽  
Clarence Charnay ◽  
Laure Lichon ◽  
Mokhtar Férid ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Doxorubicin Delivery

Design and application of a smart nanodevice by combining cationic drug delivery and hyperthermia for cancer apoptosis

2016 ◽  
Vol 4 (4) ◽  
pp. 785-792 ◽  
Author(s):  
Arathyram Ramachandra Kurup Sasikala ◽  
Afeesh Rajan Unnithan ◽  
Chan Hee Park ◽  
Cheol Sang Kim
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Anticancer Mechanism ◽  
Doxorubicin Delivery ◽  
Design And Application

Schematic illustration of the synergistic anticancer mechanism exhibited by smart mesoporous silica nanoparticles by combining cationic doxorubicin delivery with hyperthermia.

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