Characterization of an α-Calcium Sulfate Hemihydrates/α-Tricalcium Phosphate Combined Injectable Bone Cement

2018 ◽  
Vol 1 (3) ◽  
pp. 768-776 ◽  
Author(s):  
Dicheng Yang ◽  
Yinan Yan ◽  
Xunwei Liu ◽  
Ping Wang ◽  
Gang Huang ◽  
...  
Keyword(s):  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Calcium Sulfate

Preparation and characterization of a silk fibroin/calcium sulfate bone cement

2017 ◽  
Vol 106 (2) ◽  
pp. 512-519 ◽  
Author(s):  
Fuzhan Zhang ◽  
Hai Zhu ◽  
Genlin Wang ◽  
Jile Xie ◽  
Yunxia Tao ◽  
...  
Keyword(s):  
Bone Cement ◽  
Silk Fibroin ◽  
Calcium Sulfate

Synthesis and characterization of electrospun bioactive glass nanofibers-reinforced calcium sulfate bone cement and its cell biological response

2020 ◽  
Vol 46 (8) ◽  
pp. 10029-10039 ◽  
Author(s):  
Mehdi Shams ◽  
Nader Nezafati ◽  
Delaram Poormoghadam ◽  
Siamak Zavareh ◽  
Ali Zamanian ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Bone Cement ◽  
Calcium Sulfate ◽  
Biological Response ◽  
Synthesis And Characterization

scholarly journals Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

2012 ◽  
Vol 05 (08) ◽  
pp. 448-456 ◽  
Author(s):  
Loreley Morejón-Alonso ◽  
Raúl García Carrodeguas ◽  
Luis Alberto dos Santos
Keyword(s):  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Composite Bone

scholarly journals Antibiotic loaded β-tricalcium phosphate/calcium sulfate for antimicrobial potency, prevention and killing efficacy of Pseudomonas aeruginosa and Staphylococcus aureus biofilms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nan Jiang ◽  
Devendra H. Dusane ◽  
Jacob R. Brooks ◽  
Craig P. Delury ◽  
Sean S. Aiken ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Calcium Sulfate ◽  
Bone Graft Substitute ◽  
In Vitro Assays ◽  
In Vivo Experiments ◽  
Orthopaedic Infections ◽  
Clinical Investigations ◽  
Antimicrobial Potency

AbstractThis study investigated the efficacy of a biphasic synthetic β-tricalcium phosphate/calcium sulfate (β-TCP/CS) bone graft substitute for compatibility with vancomycin (V) in combination with tobramycin (T) or gentamicin (G) evidenced by the duration of potency and the prevention and killing efficacies of P. aeruginosa (PAO1) and S. aureus (SAP231) biofilms in in vitro assays. Antibiotic loaded β-TCP/CS beads were compared with antibiotic loaded beads formed from a well characterized synthetic calcium sulfate (CS) bone void filler. β-TCP/CS antibiotic loaded showed antimicrobial potency against PAO1 in a repeated Kirby-Bauer like zone of inhibition assay for 6 days compared to 8 days for CS. However, both bead types showed potency against SAP231 for 40 days. Both formulations loaded with V + T completely prevented biofilm formation (CFU below detection limits) for the 3 days of the experiment with daily fresh inoculum challenges (P < 0.001). In addition, both antibiotic loaded materials and antibiotic combinations significantly reduced the bioburden of pre-grown biofilms by between 3 and 5 logs (P < 0.001) with V + G performing slightly better against PAO1 than V + T. Our data, combined with previous data on osteogenesis suggest that antibiotic loaded β-TCP/CS may have potential to stimulate osteogenesis through acting as a scaffold as well as simultaneously protecting against biofilm infection. Future in vivo experiments and clinical investigations are warranted to more comprehensively evaluate the use of β-TCP/CS in the management of orthopaedic infections.

Elution characteristics and mechanical properties of calcium sulfate-loaded bone cement containing teicoplanin

2007 ◽  
Vol 12 (2) ◽  
pp. 170-177 ◽  
Author(s):  
Tolga Tuzuner ◽  
Ilyas Uygur ◽  
Irfan Sencan ◽  
Ugur Haklar ◽  
Birhan Oktas ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Cement ◽  
Calcium Sulfate

Preparation and Characterization of Clay Aerogel Composites Reinforced by Calcium Sulfate Whisker

2018 ◽  
Vol 18 (11) ◽  
pp. 7896-7901 ◽  
Author(s):  
Lixiu Yang ◽  
Yuchen Lu ◽  
Fuan He ◽  
Huijun Wu ◽  
Tao Xu ◽  
...  
Keyword(s):  
Calcium Sulfate ◽  
Calcium Sulfate Whisker
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