Characteristic Synthesis of a Covalent Organic Framework and Its Application in Multifunctional Tumor Therapy

2021 ◽  
Author(s):  
Shengnan Zhou ◽  
Tao Meng ◽  
Danyou Hu ◽  
Yuheng Zhu ◽  
Chenguang Huang ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Covalent Organic Framework ◽  
Organic Framework

Cell membrane-anchoring covalent organic framework nanosheets for single-laser-triggered synergistic tumor therapy

2021 ◽  
Author(s):  
Yuanyuan Chen ◽  
Tong Wu ◽  
Shujie Liu ◽  
Wei Pan ◽  
Na Li ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Laser Irradiation ◽  
Tumor Therapy ◽  
Covalent Organic Framework ◽  
Single Laser ◽  
Membrane Anchoring ◽  
Organic Framework

Herein, pH low insertion peptide (pHLIP) engineered covalent organic framework nanosheets (COF NSs) were developed for cell membrane-anchoring synergistic tumor therapy under single laser irradiation.

A Glycosylated Covalent Organic Framework Equipped with BODIPY and CaCO 3 for Synergistic Tumor Therapy

2020 ◽  
Vol 132 (41) ◽  
pp. 18198-18203
Author(s):  
Qun Guan ◽  
Le‐Le Zhou ◽  
Fan‐Hong Lv ◽  
Wen‐Yan Li ◽  
Yan‐An Li ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Covalent Organic Framework ◽  
Organic Framework

A Glycosylated Covalent Organic Framework Equipped with BODIPY and CaCO 3 for Synergistic Tumor Therapy

2020 ◽  
Vol 59 (41) ◽  
pp. 18042-18047 ◽  
Author(s):  
Qun Guan ◽  
Le‐Le Zhou ◽  
Fan‐Hong Lv ◽  
Wen‐Yan Li ◽  
Yan‐An Li ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Covalent Organic Framework ◽  
Organic Framework

Tuning the pore structures and photocatalytic properties of a 2D covalent organic framework with multi-branched photoactive moieties

Nanoscale ◽  
2020 ◽  
Vol 12 (30) ◽  
pp. 16136-16142
Author(s):  
Xuan Wang ◽  
Ming-Jie Dong ◽  
Chuan-De Wu
Keyword(s):  
Photocatalytic Properties ◽  
Effective Strategy ◽  
Covalent Organic Framework ◽  
Highly Efficient ◽  
Pore Structures ◽  
Local Connection ◽  
Organic Framework

An effective strategy to incorporate accessible metalloporphyrin photoactive sites into 2D COFs by establishing a 3D local connection for highly efficient photocatalysis was developed.

A Three-Dimensional Tetraphenylethylene-Based Fluorescence Covalent Organic Framework for Molecular Recognition

2020 ◽  
Author(s):  
Junxia Ren ◽  
Yaozu Liu ◽  
Xin Zhu ◽  
Yangyang Pan ◽  
Yujie Wang ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Fluorescence Probe ◽  
Three Dimensional ◽  
Hazardous Substances ◽  
Covalent Organic Framework ◽  
Highly Sensitive ◽  
Volatile Organic ◽  
Polycyclic Aromatic ◽  
Better Than ◽  
Organic Framework

<p><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a>The development of highly-sensitive recognition of </a><a></a><a></a><a></a><a></a><a>hazardous </a>chemicals, such as volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs), is of significant importance because of their widespread social concerns related to environment and human health. Here, we report a three-dimensional (3D) covalent organic framework (COF, termed JUC-555) bearing tetraphenylethylene (TPE) side chains as an aggregation-induced emission (AIE) fluorescence probe for sensitive molecular recognition.<a></a><a> </a>Due to the rotational restriction of TPE rotors in highly interpenetrated framework after inclusion of dimethylformamide (DMF), JUC-555 shows impressive AIE-based strong fluorescence. Meanwhile, owing to the large pore size (11.4 Å) and suitable intermolecular distance of aligned TPE (7.2 Å) in JUC-555, the obtained material demonstrates an excellent performance in the molecular recognition of hazardous chemicals, e.g., nitroaromatic explosives, PAHs, and even thiophene compounds, via a fluorescent quenching mechanism. The quenching constant (<i>K</i><sub>SV</sub>) is two orders of magnitude better than those of other fluorescence-based porous materials reported to date. This research thus opens 3D functionalized COFs as a promising identification tool for environmentally hazardous substances.</p>

scholarly journals 18.1% single palladium atom catalysts on mesoporous covalent organic framework for gas phase hydrogenation of ethylene

2021 ◽  
Vol 2 (7) ◽  
pp. 100495
Author(s):  
Chun-Te Kuo ◽  
Yubing Lu ◽  
Pezhman Arab ◽  
K. Shamara Weeraratne ◽  
Hani El-Kaderi ◽  
...  
Keyword(s):  
Gas Phase ◽  
Palladium Atom ◽  
Covalent Organic Framework ◽  
Hydrogenation Of Ethylene ◽  
Organic Framework

scholarly journals CN linked covalent organic framework for the efficient adsorption of iodine in vapor and solution

RSC Advances ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 10512-10523
Author(s):  
Sanan Song ◽  
Yue Shi ◽  
Ning Liu ◽  
Fengqi Liu
Keyword(s):  
Public Safety ◽  
Nuclear Wastes ◽  
Covalent Organic Framework ◽  
Organic Framework

Volatile nuclear wastes, such as iodine, have received worldwide attention because it poses risks to public safety and pollutes the environment.

scholarly journals Covalent organic framework nanofluidic membrane as a platform for highly sensitive bionic thermosensation

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Pengcheng Zhang ◽  
Sifan Chen ◽  
Changjia Zhu ◽  
Linxiao Hou ◽  
Weipeng Xian ◽  
...  
Keyword(s):  
Thermal Sensation ◽  
Biological Response ◽  
Covalent Organic Framework ◽  
Physiological Processes ◽  
Potential Applicability ◽  
Continuous Potential ◽  
Temperature Stimulus ◽  
Nanofluidic System ◽  
Response To Temperature ◽  
Organic Framework

AbstractThermal sensation, which is the conversion of a temperature stimulus into a biological response, is the basis of the fundamental physiological processes that occur ubiquitously in all organisms from bacteria to mammals. Significant efforts have been devoted to fabricating artificial membranes that can mimic the delicate functions of nature; however, the design of a bionic thermometer remains in its infancy. Herein, we report a nanofluidic membrane based on an ionic covalent organic framework (COF) that is capable of intelligently monitoring temperature variations and expressing it in the form of continuous potential differences. The high density of the charged sites present in the sub-nanochannels renders superior permselectivity to the resulting nanofluidic system, leading to a high thermosensation sensitivity of 1.27 mV K−1, thereby outperforming any known natural system. The potential applicability of the developed system is illustrated by its excellent tolerance toward a broad range of salt concentrations, wide working temperatures, synchronous response to temperature stimulation, and long-term ultrastability. Therefore, our study pioneers a way to explore COFs for mimicking the sophisticated signaling system observed in the nature.

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