Gentamicin-Releasing Titania Nanotube Surfaces Inhibit Bacteria and Support Adipose-Derived Stem Cell Growth in Cocultures

2021 ◽  
Author(s):  
Tara Wigmosta ◽  
Ketul Popat ◽  
Matt J. Kipper
Keyword(s):  
Stem Cell ◽  
Cell Growth ◽  
Titania Nanotube ◽  
Adipose Derived Stem Cell

scholarly journals Abstract P40. Platelet Rich Plasma Augments Adipose-Derived Stem Cell Growth and Differentiation

2017 ◽  
Vol 5 ◽  
pp. 20-21
Author(s):  
Robert P. Gersch ◽  
Joshua Glahn ◽  
Michael G. Tecce ◽  
Anthony J. Wilson ◽  
Ivona Percec
Keyword(s):  
Stem Cell ◽  
Cell Growth ◽  
Platelet Rich Plasma ◽  
Cell Growth And Differentiation ◽  
Adipose Derived Stem Cell

A polydopamine peptide coating enables adipose-derived stem cell growth on the silicone surface of cochlear implant electrode arrays

2017 ◽  
Vol 106 (4) ◽  
pp. 1431-1438 ◽  
Author(s):  
Philipp Schendzielorz ◽  
Kristen Rak ◽  
Katrin Radeloff ◽  
Johannes Völker ◽  
Thomas Gehrke ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Growth ◽  
Cochlear Implant ◽  
Electrode Arrays ◽  
Silicone Surface ◽  
Adipose Derived Stem Cell ◽  
Peptide Coating

Effect of crystalline phases of titania nanotube arrays on adipose derived stem cell adhesion and proliferation

2019 ◽  
Vol 103 ◽  
pp. 109850 ◽  
Author(s):  
Marcela Ferreira Dias-Netipanyj ◽  
Kari Cowden ◽  
Luciane Sopchenski ◽  
Sheron Campos Cogo ◽  
Selene Elifio-Esposito ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Adhesion ◽  
Nanotube Arrays ◽  
Crystalline Phases ◽  
Titania Nanotube Arrays ◽  
Titania Nanotube ◽  
Adipose Derived Stem Cell ◽  
Cell Adhesion And Proliferation

scholarly journals Platelet Rich Plasma Augments Adipose-Derived Stem Cell Growth and Differentiation

2017 ◽  
Author(s):  
Robert P. Gersch ◽  
Joshua Glahn ◽  
Michael G. Tecce ◽  
Anthony J. Wilson ◽  
Ivona Percec
Keyword(s):  
Stem Cell ◽  
Cell Growth ◽  
Platelet Rich Plasma ◽  
Cell Growth And Differentiation ◽  
Adipose Derived Stem Cell

scholarly journals Cellulose Nanofiber-Based Hydrogels Embedding 5-FU Promote Pyroptosis Activation in Breast Cancer Cells and Support Human Adipose-Derived Stem Cell Proliferation, Opening New Perspectives for Breast Tissue Engineering

Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1189
Author(s):  
Liliana-Roxana Balahura ◽  
Sorina Dinescu ◽  
Mihaela Balaș ◽  
Alexandra Cernencu ◽  
Adriana Lungu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Growth ◽  
Tumor Cells ◽  
Breast Tumor ◽  
Culture Media ◽  
Cellulose Nanofibers ◽  
Ros Generation ◽  
Soft Tissue Reconstruction ◽  
Caspase 1 ◽  
Adipose Derived Stem Cell

The structure and biocompatibility analysis of a hydrogel based on cellulose nanofibers (CNFs) combined with alginate/pectin (A.CNF or P.CNF) and enriched with 1% or 5% 5-FU revealed more favorable properties for the cellular component when pectin was dispersed within CNFs. 5-Fluorouracil (5-FU) is an antimetabolite fluoropyrimidine used as antineoplastic drug for the treatment of multiple solid tumors. 5-FU activity leads to caspase-1 activation, secretion and maturation of interleukins (IL)-1, IL-18 and reactive oxygen species (ROS) generation. Furthermore, the effects of embedding 5-FU in P.CNF were explored in order to suppress breast tumor cell growth and induce inflammasome complex activation together with extra- and intracellular ROS generation. Exposure of tumor cells to P.CNF/5-FU resulted in a strong cytotoxic effect, an increased level of caspase-1 released in the culture media and ROS production—the latter directly proportional to the concentration of anti-tumor agent embedded in the scaffolds. Simultaneously, 5-FU determined the increase of p53 and caspase-1 expressions, both at gene and protein levels. In conclusion, P.CNF/5-FU scaffolds proved to be efficient against breast tumor cells growth due to pyroptosis induction. Furthermore, biocompatibility and the potential to support human adipose-derived stem cell growth were demonstrated, suggesting that these 3D systems could be used in soft tissue reconstruction post-mastectomy.

Sign in / Sign up

Export Citation Format

Share Document