Surface Biochemical Modification of Poly(dimethylsiloxane) for Specific Immune Cytokine Response

2021 ◽  
Vol 4 (2) ◽  
pp. 1307-1318
Author(s):  
Etienne Laborie ◽  
Fabien Bayle ◽  
David Bouville ◽  
Claire Smadja ◽  
Elisabeth Dufour-Gergam ◽  
...  
Keyword(s):  
Cytokine Response ◽  
Biochemical Modification

High glucose induces donors-specific cytokine response in primary human M1 and M2 macrophages

2015 ◽  
Vol 10 (S 01) ◽  
Author(s):  
K Moganti ◽  
F Li ◽  
S Riehman ◽  
H Klüter ◽  
M Harmsen ◽  
...  
Keyword(s):  
High Glucose ◽  
Cytokine Response ◽  
M2 Macrophages ◽  
M1 And M2 Macrophages

The cytokine response of circulating immune cells to rhinovirus is reduced in severe asthma

2020 ◽  
Author(s):  
K Jamal Jameel ◽  
S Yanik ◽  
E Bülthoff ◽  
F Yusuf ◽  
B Struck ◽  
...  
Keyword(s):  
Severe Asthma ◽  
Immune Cells ◽  
Cytokine Response

The Modification and Design of Antimicrobial Peptide

2018 ◽  
Vol 24 (8) ◽  
pp. 904-910 ◽  
Author(s):  
Yidan Gao ◽  
Hengtong Fang ◽  
Lu Fang ◽  
Dawei Liu ◽  
Jinsong Liu ◽  
...  
Keyword(s):  
Chemical Modification ◽  
Antimicrobial Peptide ◽  
Protein Modification ◽  
Recent Progress ◽  
Therapeutic Agents ◽  
Manufacturing Cost ◽  
Commercial Development ◽  
Biochemical Modification ◽  
Naturally Occurring ◽  
Application Prospects

The antimicrobial peptides (AMPs) are a group of unique naturally occurring anti-microbial compounds with around 50 amino acids. It represents promising therapeutic agents to the infectious disease without concerning about drug resistance. However, commercial development of these peptides for even the simplest application has been hindered by the limitations of sources, instability, toxicity and bioavailability. To improve the properties of the artificial synthesized AMPs, the modification and design are the hotspots of the AMPs research. In fact, more than half of the known AMPs are naturally modified. In this review, two types of modification strategies, biochemical modification and chemical modification were summarized. Although, the chemical modification is versatile and direct, the manufacturing cost is greatly increased compared to the antibiotics. With the recent progress of the protein modification enzyme, the biochemical modification of the antimicrobial peptide followed by heterologous expression has great application prospects.

Human β‐defensin 3 binds to hemagglutinin B (rHagB), a non‐fimbrial adhesin from Porphyromonas gingivalis , and attenuates a pro‐inflammatory cytokine response

2008 ◽  
Vol 86 (8) ◽  
pp. 643-649 ◽  
Author(s):  
Lindsey C Pingel ◽  
Karl G Kohlgraf ◽  
Christopher J Hansen ◽  
Christopher G Eastman ◽  
Deborah E Dietrich ◽  
...  
Keyword(s):  
Porphyromonas Gingivalis ◽  
Inflammatory Cytokine ◽  
Cytokine Response ◽  
Inflammatory Cytokine Response ◽  
Fimbrial Adhesin

Does N-Acetyl-L-Cysteine Influence Cytokine Response During Early Human Septic Shock?

CHEST Journal ◽  
1998 ◽  
Vol 113 (6) ◽  
pp. 1616-1624 ◽  
Author(s):  
Herbert Spapen ◽  
Haibo Zhang ◽  
Christian Demanet ◽  
Wim Vleminckx ◽  
Jean-Louis Vincent ◽  
...  
Keyword(s):  
Septic Shock ◽  
Cytokine Response ◽  
Human Septic Shock ◽  
Early Human
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