Versatile Nanoplatform Loaded with Doxorubicin and Graphene Quantum Dots/Methylene Blue for Drug Delivery and Chemophotothermal/Photodynamic Synergetic Cancer Therapy

2020 ◽  
Vol 3 (10) ◽  
pp. 7122-7132
Author(s):  
Junlong Liang ◽  
Jianjun Liu ◽  
Xiaokang Jin ◽  
Shuting Yao ◽  
Biling Chen ◽  
...  
2019 ◽  
Vol 4 (20) ◽  
pp. 6004-6012 ◽  
Author(s):  
Junlong Liang ◽  
Qianwei Huang ◽  
Chenxiang Hua ◽  
Jinhua Hu ◽  
Biling Chen ◽  
...  

Nanomedicine ◽  
2019 ◽  
Vol 14 (15) ◽  
pp. 2011-2025 ◽  
Author(s):  
Zhen Li ◽  
Jialong Fan ◽  
Chunyi Tong ◽  
Hongyan Zhou ◽  
Wenmiao Wang ◽  
...  

Aim: Constructing a new drug-delivery system using carboxylated graphene quantum dots (cGQDs) for tumor chemotherapy in vivo. Materials & methods: A drug-delivery system was synthesized through a crosslink reaction of cGQDs, NH2-poly(ethylene glycol)-NH2 and folic acid. Results: A drug delivery system of folic acid-poly(ethylene glycol)-cGQDs was successfully constructed with ideal entrapment efficiency (97.5%) and drug-loading capacity (40.1%). Cell image indicated that the nanosystem entered into human cervical cancer cells mainly through macropinocytosis-dependent pathway. In vivo experiments showed the outstanding antitumor ability and low systemic toxicity of this nanodrug-delivery system. Conclusion: The newly developed drug-delivery system provides an important alternative for tumor therapy without causing systemic adverse effects.


2020 ◽  
Vol 3 (3) ◽  
pp. 1900183 ◽  
Author(s):  
Fatemeh Nasrollahi ◽  
Barindra Sana ◽  
David Paramelle ◽  
Samad Ahadian ◽  
Ali Khademhosseini ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51790-51798 ◽  
Author(s):  
Sima Umrao ◽  
Poornima Sharma ◽  
Anushka Bansal ◽  
Ranjna Sinha ◽  
Ranjan K. Singh ◽  
...  

Efficient visible light photodegradation of methylene blue using multi-layered graphene quantum dots (MLGQDs) has been studied with clear mechanism.


2017 ◽  
Vol 78 ◽  
pp. 1203-1211 ◽  
Author(s):  
Preeti Nigam Joshi ◽  
Sachin Agawane ◽  
Meghana C. Athalye ◽  
Vrushali Jadhav ◽  
Dhiman Sarkar ◽  
...  

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