Decorating Vitamin B6 Cofactor over Beta-Cyclodextrin Stabilized Silver Nanoparticles through Inclusion Complexation for Fluorescent Turn-On Detection of Hydrazine

2020 ◽  
Vol 3 (10) ◽  
pp. 7021-7028
Author(s):  
Vinita Bhardwaj ◽  
SK Ashok Kumar ◽  
Suban K Sahoo
Keyword(s):  
Silver Nanoparticles ◽  
Vitamin B6 ◽  
Inclusion Complexation ◽  
Turn On ◽  
Beta Cyclodextrin

Vitamin B6 cofactors guided highly selective fluorescent turn-on sensing of histamine using beta-cyclodextrin stabilized ZnO quantum dots

2020 ◽  
Vol 320 ◽  
pp. 126611 ◽  
Author(s):  
Ashish Yadav ◽  
Yachana Upadhyay ◽  
Rati Kanta Bera ◽  
Suban K. Sahoo
Keyword(s):  
Quantum Dots ◽  
Vitamin B6 ◽  
Turn On ◽  
Beta Cyclodextrin ◽  
Zno Quantum Dots

scholarly journals Inclusion complexation of .BETA.-cyclodextrin with some sulfonamides in aqueous solution.

1978 ◽  
Vol 26 (4) ◽  
pp. 1162-1167 ◽  
Author(s):  
KANETO UEKAMA ◽  
FUMITOSHI HIRAYAMA ◽  
MASAKI OTAGIRI ◽  
YOUKO OTAGIRI ◽  
KEN IKEDA
Keyword(s):  
Aqueous Solution ◽  
Inclusion Complexation ◽  
Beta Cyclodextrin

scholarly journals EVALUATION OF INNOVATED FORMULA OF BISACODYL SUPPOSITORY FOLLOWING THE DISSOLUTION PROFILE AND STABILITY DATA USING DEVELOPED HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD

2020 ◽  
Author(s):  
KAHTAN J HASSON ◽  
ESRAA G JABAR ◽  
IHAB I ALKHALIFA
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Alkaline Medium ◽  
High Performance ◽  
Inclusion Complexation ◽  
Stability Study ◽  
Dissolution Profile ◽  
Chromatography Method ◽  
Beta Cyclodextrin ◽  
Liquid Chromatography Method

Objective: Bisacodyl is a laxative drug used in the treatment of constipation, it is soluble in mineral acids, but it is practically insoluble in water. Therefore, it is very hard task to dissolve bisacodyl in alkaline medium so the objective of this study was the development of proper dissolution method for a new formulation of bisacodyl suppositories in a medium simulated to rectal region. Obviously, most of the bisacodyl suppositories preparation products will yield low percentages of dissolution in the alkaline medium of phosphate buffer pH 7.2. Methods: Preparation inclusion complex of bisacodyl with the solubilizing agent beta-cyclodextrin then incorporated in a suppository base. The quantitative analysis of bisacodyl in suppositories was carried by a developed and validated high-performance liquid chromatography method. Results and Discussion: The dissolution rates for the innovated formulation of bisacodyl complexed with beta-cyclodextrin suppositories were in average of 97.5% and the stored suppositories of this formulation maintained their specified physical and chemical properties along the real stability study. Conclusion: The application of the inclusion complexation technique of bisacodyl with beta-cyclodextrin in the production of suppositories enhances the dissolution rate and improves the stability of suppositories performance.

Spectroscopic and theoretical study on inclusion complexation of beta-cyclodextrin with permethrin

2010 ◽  
Vol 981 (1-3) ◽  
pp. 194-203 ◽  
Author(s):  
Wei Li ◽  
Bitai Lu ◽  
Aiguo Sheng ◽  
Feng Yang ◽  
Zhendong Wang
Keyword(s):  
Theoretical Study ◽  
Inclusion Complexation ◽  
Beta Cyclodextrin

Construction of highly sensitive surface-enhanced Raman scattering (SERS) nanosensor aimed for the testing of glucose in urine

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 53800-53803 ◽  
Author(s):  
Dan Sun ◽  
Guohua Qi ◽  
Shuping Xu ◽  
Weiqing Xu
Keyword(s):  
Silver Nanoparticles ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Turn On ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A facile, highly sensitive “turn on” SERS nanosensor for the detection of glucose in urine has been developed based on the aggregation of the 4-mercaptophenylboronic acid decorated silver nanoparticles in the specific bonding to glucose.

scholarly journals Cavity Closure of 2-Hydroxypropyl-β-cyclodextrin: Replica Exchange Molecular Dynamics Simulations

2019 ◽  
Author(s):  
Khanittha Kerdpol ◽  
Jintawee Kicuntod ◽  
Peter Wolschann ◽  
Seiji Mori ◽  
Chompoonut Rungnim ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Conformational Changes ◽  
Inclusion Complexation ◽  
Water Soluble ◽  
Replica Exchange ◽  
Radius Of Gyration ◽  
Replica Exchange Molecular Dynamics ◽  
Beta Cyclodextrin ◽  
Dynamics Simulations

2-Hydroxypropyl-β-cyclodextrin (HPβCD) has unique properties to enhance the stability and the solubility of low water-soluble compounds by inclusion complexation. Understanding of the structural properties of HPβCD and its derivatives based on the number of 2-hydroxypropyl (HP) substituents at the a-D-glucopyranose subunits is rather important. In this work, replica exchange molecular dynamics simulations were performed to investigate the conformational changes of single- and double-sided HP-substitution called as 6-HPβCDs and 2,6-HPβCDs, respectively. The results show that glucose subunits in both 6-HPβCDs and 2,6-HPβCDs have lower chance to flip than in βCD. Also, HP groups are occasionally blocking the hydrophobic cavity of HPβCDs, thus hindering the drug inclusion. We found that HPβCDs with high number of HP-substitutions are more likely to be blocked, while HPβCDs with double-sided HP-substitution are even more probable to be blocked. Overall, 6-HPβCDs with three and four HP-substitutions are highlighted as the most suitable structures for guest encapsulation based on our conformational analyses such as structural distortion, radius of gyration, circularity and cavity self-closure of the HPβCDs.

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