Interplay of Self-Assembling Aromatic Amino Acids and Functionalized Gold Nanoparticles Generating Supramolecular Structures

2020 ◽  
Vol 3 (9) ◽  
pp. 6196-6203
Author(s):  
Prabhjot Singh ◽  
Nikesh Narang ◽  
Rohit K. Sharma ◽  
Nishima Wangoo
Keyword(s):  
Amino Acids ◽  
Gold Nanoparticles ◽  
Aromatic Amino Acids ◽  
Supramolecular Structures ◽  
Functionalized Gold Nanoparticles ◽  
Self Assembling

scholarly journals Ru(ii)-polypyridyl surface functionalised gold nanoparticles as DNA targeting supramolecular structures and luminescent cellular imaging agents

Nanoscale ◽  
2016 ◽  
Vol 8 (1) ◽  
pp. 563-574 ◽  
Author(s):  
Miguel Martínez-Calvo ◽  
Kim N. Orange ◽  
Robert B. P. Elmes ◽  
Bjørn la Cour Poulsen ◽  
D. Clive Williams ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cellular Imaging ◽  
Supramolecular Structures ◽  
Imaging Agents ◽  
Dna Targeting ◽  
Functionalized Gold Nanoparticles ◽  
Average Size

The development of 15 nm (average size) Ru(ii) functionalized gold nanoparticles 1–3·AuNP is described.

Investigating the Interaction Mechanism of Gold Nanoparticles with Mercapto Amino Acids

2013 ◽  
Vol 645 ◽  
pp. 43-46
Author(s):  
Hui Qing Li ◽  
Xiu Fang Wang ◽  
Jun Zhang ◽  
Xiao Wei Di
Keyword(s):  
Amino Acids ◽  
Gold Nanoparticles ◽  
Amino Acid ◽  
Interaction Mechanism ◽  
Functionalized Gold Nanoparticles

Biomolecule functionalized gold nanoparticles offer a broad range of applications in biomedical and bioanalytical areas. In this work, we investigated the spectroscopy behavior of gold nanoparticles modified with mercapto amino acid, cysteine. We found that the interaction of gold nanoparticles with cysteine resulted in a shift in the plasmon bands to higher wavelengths at the lower concentration of cysteine and in acidity solution.

Self-Assembling l-d-l-Tripeptides Dance the Twist

Synlett ◽  
2020 ◽  
Vol 31 (05) ◽  
pp. 434-438 ◽  
Author(s):  
Maria C. Cringoli ◽  
Ottavia Bellotto ◽  
Rita De Zorzi ◽  
Attilio V. Vargiu ◽  
Silvia Marchesan
Keyword(s):  
Molecular Dynamics ◽  
Amino Acids ◽  
Single Crystal ◽  
Self Assembly ◽  
Building Blocks ◽  
Supramolecular Structures ◽  
X Ray Diffraction ◽  
Supramolecular Materials ◽  
X Ray ◽  
Self Assembling

Minimalistic peptides composed of d- and l-amino acids are attractive building blocks for functional supramolecular materials, including catalysts. d-Amino acids have long been known to promote turn conformations in peptides, yet unexpected twists continue to emerge on their effects on self-assembly. The combination of single-crystal X-ray diffraction and full-atom molecular dynamics have finally unraveled fine details of how l-d-l-tripeptides visit different conformations in solution and establish key interactions in supramolecular structures.

scholarly journals Facile fabrication of lipase to amine functionalized gold nanoparticles to enhance stability and activity

RSC Advances ◽  
2017 ◽  
Vol 7 (68) ◽  
pp. 42845-42855 ◽  
Author(s):  
Sristy Shikha ◽  
Krishan Gopal Thakur ◽  
Mani Shankar Bhattacharyya
Keyword(s):  
Amino Acids ◽  
Gold Nanoparticles ◽  
Functionalized Gold Nanoparticles ◽  
Acidic Amino Acids ◽  
Amine Functionalized ◽  
Facile Fabrication

Schematic illustration of the formation of a AuNPs-NH2-lipase nanozyme composite involving activation of accessible acidic amino acids (Step 1), and conjugation to amine functionalized gold nanoparticles (Step 2).

scholarly journals SAPdb: A database of nanostructures formed by self-assembly of short peptides

2019 ◽  
Author(s):  
Deepika Mathur ◽  
Harpreet Kaur ◽  
Anjali Dhall ◽  
Neelam Sharma ◽  
Gajendra P. S. Raghava
Keyword(s):  
Amino Acids ◽  
Self Assembly ◽  
Aromatic Amino Acids ◽  
The Self ◽  
Single Amino Acid ◽  
Short Peptides ◽  
Experimental Conditions ◽  
Surface Receptors ◽  
Self Assembling ◽  
Comprehensive Information

AbstractBackgroundNanostructures generated by self-assembly of peptides yield nanomaterial that has many therapeutic applications, including drug delivery and biomedical engineering, due to their low cytotoxicity and higher uptake by targeted cells owing to their high affinity and specificity towards cell surface receptors. Despite the promising implications of this rapidly expanding field, there is no dedicated resource to study peptide nanostructures.ResultThis study endeavours to create a dedicated repository of short peptides, which may prove to be the best models to study ordered nanostructures formed by peptide self-assembly. SAPdb has a repertoire of 1,049 entries of experimentally validated nanostructures formed by the self-assembling of small peptides. It includes 701 entries are of dipeptides, 328 entries belong to tripeptides, and 20 entries of single amino acid with some conjugated partners. Each entry encompasses comprehensive information about the peptide such as chemical modifications in the peptide sequences, the type of nanostructure formed, and experimental conditions like pH, temperature, and solvent required for the self-assembly of the peptide, etc. Further, our analysis has shown that the occurrence of aromatic amino acids favours the formation of self-assembling nanostructures, as indicated by a large number of entries in SAPdb contain aromatics amino acids. Besides, we have observed that these peptides form different nanostructures under different experimental conditions. SAPdb provides this comprehensive information in a hassle-free tabulated manner at a glance. User-friendly browsing, searching, and analysis modules are integrated for easy retrieval and comparison of data and examination of properties. We anticipate SAPdb to be a valuable repository for researchers engaged in the burgeoning arena of nanobiotechnology.AvailabilityThe database can be accessed on the web at https://webs.iiitd.edu.in/raghava/sapdb.

Smart phone assisted, rapid, simplistic, straightforward and sensitive biosensing of cysteine over other essential amino acids by β-cyclodextrin functionalized gold nanoparticles as a colorimetric probe

2020 ◽  
Vol 44 (28) ◽  
pp. 12169-12177 ◽  
Author(s):  
Ramar Rajamanikandan ◽  
Asokan Dhivya Lakshmi ◽  
Malaichamy Ilanchelian
Keyword(s):  
Amino Acids ◽  
Gold Nanoparticles ◽  
Colorimetric Assay ◽  
Smart Phone ◽  
Essential Amino Acids ◽  
Colorimetric Probe ◽  
Functionalized Gold Nanoparticles ◽  
Functionalized Aunps

Herein, we have attempted the synthesis of β-CD functionalized AuNPs and then applied them as a colorimetric assay for the quantification of Cys over other different essential amino acids.

The Efficient Preparation of Radiolabeled Aromatic Amino Acids via Cu-Mediated Radiofluorination using Ni-complexes

2019 ◽  
Author(s):  
A Craig ◽  
N Kolks ◽  
E Urusova ◽  
BD Zlatopolskiy ◽  
B Neumaier
Keyword(s):  
Amino Acids ◽  
Aromatic Amino Acids

Long term dietary intake of aromatic amino acids are associated with leptin gene expression in adipose tissues of non-diabetic adults

2018 ◽  
Author(s):  
Golaleh Asghari ◽  
Emad Yuzbashian ◽  
Maryam Zarkesh ◽  
Parvin Mirmiran ◽  
Mehdi Hedayati ◽  
...  
Keyword(s):  
Gene Expression ◽  
Amino Acids ◽  
Dietary Intake ◽  
Aromatic Amino Acids ◽  
Adipose Tissues
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